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GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).

Anakinra (Raleukin) is a cytokine inactivator and interleukin 1 receptor antagonist that can be used to study secondary phagocytic lymphohistiocytosis and rheumatoid arthritis.

Anti-ETBR Antibody (DEDN6526A Naked Antibody) is a highly specific monoclonal antibody targeting the endothelin B receptor (ETBR) and serves as the antibody for the ADC molecule DEDN6526A. DEDN6526A (RG-7636) is a humanized ETBR-targeting antibody-drug conjugate developed for melanoma research.

Anti-EFNA4 Antibody (PF-06647263 Naked Antibody) is a monoclonal antibody targeting EFNA4 and can be used for the synthesis of the ADC PF-06647263.

Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin.

Kanakugiol is a useful organic compound for research related to life sciences. The catalog number is T124628 and the CAS number is 57499-44-2.

Vernakalant Hydrochloride (RSD1235 hydrochloride) is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.

GalNAc unconjugated/naked Xalnesiran is a form of Xalnesiran not linked to GalNAc. Xalnesiran is an siRNA used in the treatment of chronic hepatitis B (HBV).

Konakhin is a novel type of degraded sesterterpene and isolated from a marine sponge of Senegal.

Ranakinin is a novel tachykinin receptor agonist; from the brain of frog, Rana ridibunda.

Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.

ARC1905, a non-PEGylated/naked anti-C5 RNA aptamer, functions by inhibiting the cleavage of complement factor 5 (C5) into its components, C5a and C5b, without PEG conjugation. This compound is currently being researched for its potential application in the treatment of age-related macular degeneration (AMD).

Inclisiran (unconjugated/naked) is a double-stranded small interfering RNA (siRNA) that lacks GalNAc conjugation. This compound selectively inhibits the transcription of PCSK-9, making it applicable in the research of hyperlipidemia and cardiovascular disease (CVD) [1].

GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran increases thrombin generation and has the potential for the research of the hemophilia [1] .

Vunakizumab (Anti-Human IL17A Recombinant Antibody) is a human IgGκ monoclonal antibody that specifically targets and inhibits IL-17A's receptor interaction, making it useful for researching autoimmune conditions such as psoriatic arthritis, ankylosing spondylitis, multiple sclerosis, and inflammatory arthritis [1].

Anti-CD46 Antibody (FOR46 Naked Antibody) is a humanized antibody targeting CD46, used in prostate disease and myeloma research.

Anti-Mesothelin Antibody (BMS-986148 Naked Antibody) is a human monoclonal antibody targeting mesothelin and can be used for the synthesis of the ADC BMS-986148.

Anti-CLDN6 Antibody (DS-9606A Naked antibody) is an inhibitory antibody that can be used in life science related research.

Anti-TM4SF1 Antibody is a human-derived antibody expressed in CHO cells, targeting TM4SF1. It consists of a human IgG1 heavy chain and a human κ light chain, with a predicted molecular weight (MW) of 150 kDa. For isotype control reference, see HumanIgG1kappa, Isotype Control.

Sunakiment is a humanized IgG1λ monoclonal antibody inhibitor that targets thymic stromal lymphopoietin (TSLP). It is applicable for research in inflammation and immune system disorders, including ulcerative colitis, rheumatoid arthritis, allergies, and cancer.

Anti-CD33 Antibody (IMGN-779 Naked Antibody) is a humanized antibody targeting CD33 with antileukemic activity, which can be used to study leukemia.

Anti-FcRH5 Antibody (MFRF3266A, DFRF4539A Naked Antibody) is a highly specific monoclonal antibody targeting FcRH5 (also known as IRTA2 or CD307e) and serves as the antibody backbone for the ADC DFRF4539A (RG-7598), which is used in research related to relapsed or refractory multiple myeloma.

Anti-CD71/TfR1 Antibody (Jr-141 Naked Antibody) is a sophisticated humanized monoclonal antibody target the human transferrin receptor 1 (TfR1/CD71) with a measured dissociation constant (Kd) of 1.12 nM, functioning as the foundational component of the J-Brain Cargo technology for research involving receptor-mediated transcytosis across the blood-brain barrier.

p5 Ligand for Dnak and DnaJ is a nonapeptide corresponding to the primary binding sites of the 23-residue mitochondrial aspartate aminotransferase presequence. p5 ligand is a high-affinity ligand for Dnak and DnaJ.