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Results for "

chronic lymphocytic leukemia

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    23
    TargetMol | Inhibitors_Agonists
  • Inhibitory Antibodies
    5
    TargetMol | Inhibitory_Antibodies
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    TargetMol | PROTAC
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    TargetMol | Recombinant_Protein
Ibrutinib
PCI-32765
T1835936563-96-1
Ibrutinib (PCI-32765) is an irreversible inhibitor of BTK (IC50: 0.5 nM) that selectively blocks B cell activation.
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TargetMol | Citations Cited
MT-802
T161572231744-29-7
MT-802 is an effective BTK degrader based on PROTAC technology (DC50: 1 nM). MT-802 has the potential to treat C481S mutant chronic lymphocytic leukemia (CLL).
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PROTAC BTK Degrader-10
T2043822988804-46-0
PROTAC BTK Degrader-10 (Example 1P) is a PROTAC compound that targets BTK for degradation. It is applicable in the research of chronic lymphocytic leukemia (CLL). [Pink: ligand for target protein; Black: linker; Blue: ligand for E3 ligase Cereblon].
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