atp synthase

Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria.

Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase (EC 2.1.

(3S,8R,9R)-Isofalcarintriol, a natural polyacetylene compound present in carrot roots, acts as a potent longevity promoter. It improves glucose metabolism and exhibits antitumor activity by influencing cellular respiration and interacting with the α-subunit of mitochondrial ATP synthase, which promotes mitochondrial biosynthesis. Furthermore, (3S,8R,9R)-Isofalcarintriol is utilized in research related to neurodegenerative diseases, metabolic disorders, and aging.'

Oligomycin B, an antibiotic isolated from marine Streptomyces, serves as an eukaryotic ATP synthase inhibitor and induces apoptosis.