phosphatase-in-1 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78835	Phosphatase-IN-1		Antifungal
	Phosphatase-IN-1 (compound II-8), a propranolol derivative, acts as an inhibitor of phosphatidate phosphatase (Pah). It binds to MoPah1 with an affinity constant of 19.8 μM, demonstrating growth inhibition of plant patho...		Antifungal
T12901	SHIP2-IN-1		Phosphatase
	SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 µM),and used in the research of Alzheimer’s disease.		Phosphatase
T7356	PTP1B-IN-1	PTP1B inhibitor	Phosphatase
	PTP1B-IN-1 (PTP1B inhibitor) is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B) (IC50 : 1.6 mM)		Phosphatase
T60254	Calcium glycerophosphate		Phosphorylase
	Calcium glycerophosphate(CaGP) is an inhibitor of intestinal alkaline phosphatase F3. Calcium glycerophosphate can be a source of calcium and phosphorus in total parenteral nutrition solutions [1] [2].		Phosphorylase
T75349	CDP-Star
	CDP-Star, a chemiluminescent substrate specifically designed for alkaline phosphatase, is effectively utilized in enzyme-linked immunoassays (ELISA) [1].
T7084	2-Bromo-4'-hydroxyacetophenone	SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide	Phosphatase
	2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SH...		Phosphatase
T81417	PP5-IN-1		Apoptosis , Phosphatase
	PP5-IN-1 is a potent and competitive serine/threonine protein phosphatase-5 (PP5) inhibitor with potential anticancer activity that induces apoptosis in cancer cells.		Apoptosis , Phosphatase
T23479L	TT-232 TFA（147159-51-1 free base）		Others
	TT2-32 TFA induces a biphasic activation of phosphotyrosine phosphatase activity in human colon tumor cell line, SW620		Others
T9174	Icerguastat	Sephin 1,lcerguastat,IFB-088	Phosphatase
	Icerguastat (IFB-088) is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo.		Phosphatase
T14327	AS1949490		Phosphatase
	AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.		Phosphatase
T78141	LFHP-1c		Phospholipase
	LFHP-1c, a neuroprotective PGAM5 inhibitor, demonstrates efficacy in preserving blood-brain barrier integrity following ischemic stroke. It achieves this by binding to endothelial PGAM5, thereby inhibiting its phosphatas...		Phospholipase
T2P2923	Stearic acid	Isostearic acid,Octadecanoic acid,Cetylacetic acid	Phosphatase , Endogenous Metabolite
	1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have...		Phosphatase , Endogenous Metabolite
T71739	PTPMT1-IN-1
	PTPMT1-IN-1 is a PTEN-like mitochondrial phosphatase PTPMT1 inhibitor.
T28818	SMAPP1
	SMAPP1 is an activator of protein phosphatase 1 (PP1). SMAPP1 induces PP1 activity in vitro and activates latent HIV-1 provirus in cultured and primary T cells.
T11889	LTV-1		Others
	LTV-1 has the potential for autoimmunity treatment. LTV-1 is a potent lymphoid tyrosine phosphatase (LYP) inhibitor in T cells with an IC50 of 508 nM.		Others
T35777	Nodularin
	The cyanobacterium Nodularia spumigena often contaminates the drinking water of rural communities in developing countries and accumulates in mussels, flounder, and cod from the northern Baltic Sea. Nodularin is a hepatot...
T75377	Thymolphthalein monophosphate disodium hydrate
	Thymolphthalein monophosphate disodium hydrate serves as a chromogenic substrate for the detection of acid phosphatase and alkaline phosphatase. During the enzymatic reaction, thymolphthalein is liberated which elevates ...
T62724	AQX-435
	AQX-435 is a potent activator of SHIP1 (SH2 domain-containing inositol-5′-phosphatase 1). AQX-435 decreases B-cell receptor (BCR) downstream PI3K activity, induces apoptosis in malignant B cells, and exhibits inhibitory ...
T75738	Microcystin-RR
	Microcystin-RR (Cyanoviridin RR), a potent orally active inhibitor of protein phosphatase, induces apoptosis and endoplasmic reticulum (ER) stress in mouse liver [1] [2].
T79161	PROTAC PTPN2 degrader-2 TFA		Phosphatase
	PROTAC PTPN2 degrader-2 (example 187B) TFA is a potent degrader of Protein Tyrosine Phosphatase Non-receptor Type 2 (PTPN2), with potential applications in cancer and metabolic disease research [1].		Phosphatase