csf1r — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10894	CSF1R-IN-1		c-Fms
	CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.		c-Fms
T13194	CSF1R-IN-2		c-Fms , c-Met/HGFR , Src
	CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).		c-Fms , c-Met/HGFR , Src
T64066	CSF1R-IN-3		c-Fms , CSF-1R
	CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM. CSF1R-IN-3 has anti-proliferative activity against colorectal cancer cells. CSF1R-IN-3 exhibits anti-tumour effects and immune enhancing ef...		c-Fms , CSF-1R
T62557	CSF1R-IN-14
	CSF1R-IN-14, an isoindolinone derivative compound, is a potent inhibitor of CSF1R. CSF1R-IN-14 has potential for cancer disease research.
T79472	CSF1R-IN-17		c-Fms
	CSF1R-IN-17 (compound 9) is a potent, selective antagonist of CSF1R, exhibiting an inhibition concentration half-maximum (IC50) of 0.2 nM. It is capable of inhibiting osteoclast differentiation [1].		c-Fms
T62342	CSF1R-IN-4
	CSF1R-IN-4 is a potent inhibitor of CSF-1R. CSF1R-IN-4 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-4 has potential for the study of cancer diseases. EGFR-IN-40.
T62187	CSF1R-IN-6
	CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF1R-IN-6 is a potent inhibitor of CSF1R, which is expressed in macrophages and is dependent on the CSF-1/CSF-1R signalling pathway for survival and differentiation of macropha...
T62364	CSF1R-IN-5
	CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF1R-IN-5 can affect the exchange of inflammatory factors between TAM and glioma cells. CSF1R-IN-5 has the potential to be used in the study of cancer diseases.
T62190	CSF1R-IN-7
	CSF1R-IN-7 (Formula I) is a CSF-1R inhibitor that can be used to study Alzheimer's disease.
T61893	CSF1R-IN-12
	CSF1R-IN-12 is an effective CSF1R inhibitor. CSF1R-IN-12 has research potential in cancer diseases.
T61554	CSF1R-IN-13
	CSF1R-IN-13 is a powerful CSF1R inhibitor with potential applications in researching cancer diseases [1]. CSF1R, also known as colony stimulating factor 1 receptor, is a critical growth factor that regulates various cell...
T62318	CSF1R-IN-9
	CSF1R-IN-9 (Compound 46) is a CSF-1R inhibitor (IC50: 0.028 μM).
T62313	CSF1R-IN-10
	CSF1R-IN-10 (Compound 48) is a CSF-1R inhibitor (IC50: 0.005 μM).
T62390	CSF1R-IN-8
	CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor (IC50: 0.012 μM).
T72574	Axl/Mer/CSF1R-IN-1
	Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds) of less than 0.1 μM.
T5586	CFMS Receptor Inhibitor II		c-Fms
	cFMS Receptor Inhibitor II is a CSF1R kinase inhibitor		c-Fms
T14380	AZD7507		CSF-1R , HER , Sodium Channel
	AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.		CSF-1R , HER , Sodium Channel
T6119	Sotuletinib	BLZ945	c-Fms , CSF-1R
	Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.		c-Fms , CSF-1R
T10652	Vimseltinib	DCC-3014	c-Fms , CSF-1R , c-Kit
	Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).		c-Fms , CSF-1R , c-Kit
TQ0015	PRN1371		c-Fms , FGFR , CSF-1R
	PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).		c-Fms , FGFR , CSF-1R