Decarboxylase

α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synthase and mTOR signaling.

Carbidopa (Lodosyn) is an aromatic-L-amino-acid decarboxylase inhibitor (IC50: 29±2 μM). It is used in PARKINSON DISEASE to reduce peripheral adverse effects of LEVODOPA.

Eflornithine hydrochloride hydrate (RMI-71782 hydrochloride hydrate) is a specific, irreversible inhibitor of ornithine decarboxylase.

Carbidopa monohydrate (S(-)-Carbidopa) is an inhibitor of DOPA decarboxylase, preventing the conversion of levodopa to dopamine.

4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase.

Tritoqualine is used as an inhibitor of histidine decarboxylase.

L-Ornithine ((S)-2,5-Diaminopentanoic acid) has an anti-fatigue function in facilitating the excretion of ammonia and increasing the efficiency of energy consumption.