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Angiotensin-converting Enzyme (ACE)

Angiotensin-converting enzyme, or ACE, is a central component of the renin–angiotensin system (RAS), which controls blood pressure by regulating the volume of fluids in the body. It converts the hormone angiotensin I to the active vasoconstrictor angiotensin II. Therefore, ACE indirectly increases blood pressure by causing blood vessels to constrict. ACE inhibitors are widely used as pharmaceutical drugs for treatment of cardiovascular diseases. Other lesser known functions of ACE are degradation of bradykinin, substance P and amyloid beta-protein.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78770 Garcinone B 76996-28-6 98%
Garcinone B
Garcinone B, a xanthone derivative naturally isolated from the pericarp of Mangosteen, serves as a potent inhibitor of ACE2 and Mpro, and is utilized in COVID-19...
T79958 Isocrenatoside 221895-09-6 98%
Isocrenatoside
Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting enzyme...
T80096 L-Isoleucyl-L-arginine 55715-01-0 98%
L-Isoleucyl-L-arginine
L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in hy...
T80099 Ovalbumin (154-159) 1370698-94-4 98%
Ovalbumin (154-159)
Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in hyperten...
T80100 Ovotransferrin (328-332) 1226776-54-0 98%
Ovotransferrin (328-332)
Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also...
T5329 Trandolapril 87679-37-6 99.70%
Trandolapril
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T24588 Palatrigine 98410-36-7 98.87%
Palatrigine
Palatrigine (BW-A 256C) is a compound with angiotensin-converting enzyme inhibitory and beta-adrenergic receptor blocking properties.
T27827 Libenzapril 109214-55-3 98.74%
Libenzapril
Libenzapril (CGS 16617) is a potent angiotensin-converting enzyme inhibitor used to study myocardial injury.
T24906L Tuna AI acetate 98.49%
Tuna AI acetate
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
TP1750L H-Ile-Pro-Pro-OH acetate TP1750L 97.15%
H-Ile-Pro-Pro-OH acetate
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.
T20689 Temocaprilat 110221-53-9 96.88%
Temocaprilat
Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and t...
T68171L Zabicipril HCl 90130-77-1 100%
Zabicipril HCl
Zabicipril HCl(S 9650) is a potent angiotensin-converting enzyme inhibitor.
T16731 Rentiapril racemate 72679-47-1 100%
Rentiapril racemate
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
TN2295 Vicenin-1 35927-38-9 98%
Vicenin-1
Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity,...
Garcinone B
T78770
Garcinone B, a xanthone derivative naturally isolated from the pericarp of Mangosteen, serves as a potent inhibitor of ACE2 and Mpro, and is utilized in COVID-19...
Isocrenatoside
T79958
Isocrenatoside (compound 6), a cyclic octapeptide derived from the ethanolic extract of Microtoena prainiana stems, functions as an angiotensin-converting enzyme...
L-Isoleucyl-L-arginine
T80096
L-Isoleucyl-L-arginine, a dipeptide composed of L-isoleucine and L-arginine, acts as a potent angiotensin-converting enzyme (ACE) inhibitor and is utilized in hy...
Ovalbumin (154-159)
T80099
Ovalbumin (154-159), a peptide fragment derived from ovalbumin, acts as a potent inhibitor of the angiotensin-converting enzyme (ACE) and is utilized in hyperten...
Ovotransferrin (328-332)
T80100
Ovotransferrin (328-332), with an IC50 of 20 μM, exhibits protective activity against hypertension by inhibiting the Angiotensin-Converting Enzyme (ACE) and also...
Trandolapril
T5329
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
Palatrigine
T24588
Palatrigine (BW-A 256C) is a compound with angiotensin-converting enzyme inhibitory and beta-adrenergic receptor blocking properties.
Libenzapril
T27827
Libenzapril (CGS 16617) is a potent angiotensin-converting enzyme inhibitor used to study myocardial injury.
Tuna AI acetate
T24906L
Tuna AI acetate is an inhibitor of angiotensin-converting enzyme (ACE) in non-competitive manner derived from tuna muscle.
H-Ile-Pro-Pro-OH acetate
TP1750L
H-Ile-Pro-Pro-OH acetate is a angiotensin-converting enzyme inhibitor (ACE) of milk-derived tripeptides.
Temocaprilat
T20689
Temocaprilat (RS5139) is an Angiotensin-converting Enzyme (ACE) inhibitor. Temocaprilat is effectively excreted in bile via cMOAT that is deficient in EHBR and t...
Zabicipril HCl
T68171L
Zabicipril HCl(S 9650) is a potent angiotensin-converting enzyme inhibitor.
Rentiapril racemate
T16731
Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril.Rentiapril racemate has anti-inflammatory activity and may be used in glaucoma research.
Vicenin-1
TN2295
Vicenin-1 (Vicenin -1) is a flavonoid glycoside isolated from the seeds of the leguminous plant fenugreek with potent anti-inflammatory and antioxidant activity,...
TargetMol