urate

Uric acid is an important antioxidant that scavenges oxygen radicals and reactive oxygen species (such as singlet oxygen and peroxynitrite), inhibits lipid peroxidation, helps maintain stable blood pressure, and is the final product of purine metabolism. It is commonly used to induce hypertension models.

Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).

Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.

Uric acid sodium is a potent and widely recognized antioxidant with the ability to scavenge oxygen free radicals, helping to maintain blood pressure stability and counteract oxidative stress. It effectively eliminates reactive oxygen species (ROS), such as singlet oxygen and peroxynitrite, and inhibits lipid peroxidation. Additionally, uric acid sodium is closely associated with the pathogenesis of gouty arthritis and the formation of calcium oxalate stones, and it can be used to induce hypertension models.

Lesinurad (RDEA594) is a selective inhibitor of uric acid reabsorption which is used in combination with other agents in the therapy of gout. Lesinurad has had a limited clinical use but has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.

Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.

Urate oxidase (Uox), also known as uricase, is a peroxisomal enzyme widely utilized in biochemical research. It catalyzes the conversion of uric acid to allantoin in the majority of mammals [1].

Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.

Sorbitan monolaurate (Arlacel 20) is an dehydrated sorbitan ester surfactant commonly used in the skin care industry.

Triglycidyl isocyanurate (Teroxirone) is a triazene triepoxide with antineoplastic and antiangiogenic activity. It inhibits growth of human non-small cell lung cancer cells by activating p53. Triglycidyl isocyanurate alkylates and cross-links DNA, thereby inhibiting DNA replication. It induces cell apoptosis and can be used for cancer research[1][2]. Triglycidyl isocyanurate is also used in various polyester powder coatings in the metal finishing industry.

Isopropyl laurate can be used in coatings, inks, detergents, and other fields.

Methyl Laurate (methyl dodecanoate) is a 12-carbon saturated fatty acid and an esterified version of lauric acid[1].

Diminazene is a trypanocidal agent.

Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.

Zaurategrast ethyl ester is the ethyl ester prodrug of CT7758 and is an α4β1/α4β7 integrin antagonist. It is used for the treatment of inflammatory and autoimmune disorders.

Zaurategrast (CDP323) is a small-molecule prodrug antagonist that inhibits the interaction between vascular cell adhesion molecule 1 (VCAM-1) and α4-integrins, originally developed by Celltech plc for oral administration, and it serves as a valuable research compound for investigating leukocyte trafficking, immune cell adhesion, and therapeutic strategies relevant to multiple sclerosis.

Paracetamol Mercapturate is a metabolite of Acetaminophen. It can also be used in the biological study of urinary antihypertensive drugs.

Diminazene, an aromatic diamine compound derived from Surfen C, is commonly used in the form of its acetate salt. It exhibits high activity against both Trypanosoma and Babesia spp.

Cholesteryl Laurate is a cholesterol ester widely used in biochemical experiments and drug synthesis research.

Pentachlorophenyl laurate is used as a pesticide.

Ammonium acryloyldimethyltaurate is a bioactive chemical.

Ammonium laurate is a surfactant.

Clofibrate mercapturate is a urinary metabolite of clofibrate.

Estrofurate is a biochemical.