Search Result

Search Results for " scar "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T5102	TGN-020	TGN020	Aquaporin , PROTAC Linker
	TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.		Aquaporin , PROTAC Linker
T0220	Foscarnet sodium	Phosphonoformate	Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
	Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.		Virus Protease , Reverse Transcriptase , DNA/RNA Synthesis
T15339	Foscarbidopa	Carbidopa 4′-monophosphate	Dopamine Receptor
	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.		Dopamine Receptor
T24507	Muscarine	(+)-Muscarine,Muskarin
	Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.
T23034	Muscarine iodide	(+)-Muscarine iodide	Others
	Muscarinic acetylcholine receptor agonist		Others
T60253	(±)-Muscarine chloride
	(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].
T124690	Cascaroside A
	Cascaroside A is a useful organic compound for research related to life sciences and the catalog number is T124690.
T81893	M1/M4 muscarinic agonist 2
	Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].
T34563	Scaritoxin
	Scaritoxin is a potent toxic substance isolated from poisonous fish.
T11000	Descarbamoyl cefuroxime		Others
	Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.		Others
T80183	Muscarinic toxin 7
	Muscarinic toxin 7 (MT7) is a peptide exhibiting selective, noncompetitive antagonistic activity at the muscarinic M1 receptor [1].
T80477	Muscarinic toxin 3	MT3	Adrenergic Receptor
	Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57 for α1B, 8.13 for α1D, 8.49 for α2A, <6.5 for α2B, and 7.29 ...		Adrenergic Receptor
T20752	Biebrich scarlet	NSC-79710,NSC79710,NSC 79710
	Biebrich scarlet is a scarlet dye, it has been used in Masson’s trichrome stain for the staining of collagen. It has also been used for the staining of eosinophil.
T24508	Muscarine chloride	HSDB-3515,(+)-Muscarine chloride,HSDB 3515,L-(+)-Muscarine chloride,EINECS 218-963-2
	Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.
T2270	Trans-Tranilast	Tranilast trans-	RAAS
	Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993....		RAAS
T14139	Aganepag	AGN 210937	Prostaglandin Receptor
	Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, s...		Prostaglandin Receptor
T37598	D-Glucosamine-6-sulfate
	D-Glucosamine-6-sulfate is a naturally occurring glycosaminoglycan. It activates the glmS ribozyme from B. subtilis, a Gram-positive bacterium, when used at a concentration of 200 μM. It has been used to form polyvalent ...
T60438	PXS-6302
	PXS-6302 is an irreversible inhibitor of lysyl oxidase with IC50s of 3.7 μM for Bovine LOX, 3.4 μM for rh LOXL1, 0.4 μM for rh LOXL2, 1.5 μM for rh LOXL3, 0.3 μM for rh LOXL4, respectively. PXS-6302 can readily penetrate...

Compounds

TGN-020

T5102

Synonym: TGN020

Target: Aquaporin, PROTAC Linker

Foscarnet sodium

T0220

Synonym: Phosphonoformate

Target: Virus Protease, Reverse Transcriptase, DNA/RNA Synthesis

Foscarbidopa

T15339

Synonym: Carbidopa 4′-monophosphate

Target: Dopamine Receptor

Muscarine

T24507

Synonym: (+)-Muscarine,Muskarin

Target:

Muscarine iodide

T23034

Synonym: (+)-Muscarine iodide

Target: Others

(±)-Muscarine chloride

M1/M4 muscarinic agonist 2

Descarbamoyl cefuroxime

Target: Adrenergic Receptor

Biebrich scarlet

T20752

Synonym: NSC-79710,NSC79710,NSC 79710

Target:

Muscarine chloride

T24508

Synonym: HSDB-3515,(+)-Muscarine chloride,HSDB 3515,L-(+)-Muscarine chloride,EINECS 218-963-2

Target:

Trans-Tranilast

T2270

Synonym: Tranilast trans-

Target: Prostaglandin Receptor

D-Glucosamine-6-sulfate

Cat No.	Product Name	Synonyms	Targets
T3809	Liriope muscari baily saponins C		Others
	Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.		Others
T25114	Ascaridole	NSC-406266,NSC 406266,NSC406266	Parasite
	Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.		Parasite
T5794	Saponin C from Liriope muscari	Liriope muscari baily Saponins C
	Saponin C from Liriope muscari can be extracted from Liriope muscari, family Liliaceae.
T3876	Loureirin B		PAI-1 , ERK , Potassium Channel , JNK
	Loureirin B can downregulate the expression of fibrosis-related molecules by regulating MMPs and TIMPs levels, inhibit scar fibroblast proliferation and suppress TGF-β1-induced fibrosis, during which TGF-β1/Smad2/3 pathw...		PAI-1 , ERK , Potassium Channel , JNK
T64812	Collagenase Type I	Collagenase I,Collagenase Type I (From microorganisms)	Others
	Collagenase Type I is a proteolytic enzyme that breaks down the peptide bonds in collagen, the main structural protein of connective tissue. Collagenase has been explored as a potential treatment option to break down her...		Others

Natural Products

Liriope muscari baily saponins C

Synonym: NSC-406266,NSC 406266,NSC406266

Target: Parasite

Saponin C from Liriope muscari

T5794

Synonym: Liriope muscari baily Saponins C

Target: PAI-1, ERK, Potassium Channel, JNK

Collagenase Type I

T64812

Synonym: Collagenase I,Collagenase Type I (From microorganisms)

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02767	TPP1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit...
TMPY-01081	SR-BI/SCARB1 Protein, Human, Recombinant (His)	Human	HEK293
	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPK-01117	OSCAR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPK-01092	OSCAR Protein, Human, Recombinant (hFc)	Human	HEK293
	Osteoclast-associated receptor (OSCAR) is a co-stimulatory receptor in osteoclastogenesis. Synovial tissues from active rheumatoid arthritis (RA) patients express higher levels of OSCAR compared with osteoarthritic and n...
TMPY-05498	SR-BI/SCARB1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-01097	SR-BI/SCARB1 Protein, Mouse, Recombinant (His & hFc)	Mouse	HEK293
	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPY-01098	SR-BI/SCARB1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Scavenger receptor class B, member 1 (SCARB1), also known as CD36L1, is a member of the scavenger receptor family. SCARB1 is expressed primarily in liver and non placental steroidogenic tissues, and predominantly localiz...
TMPH-02061	SCARB1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	SCARB1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00047	DODA Protein, Amanita muscaria, Recombinant (His & Myc)	Amanita muscaria	E. coli
	Extradiol dioxygenase that opens up the cyclic ring of DOPA between carbons 4 and 5 thus producing an unstable seco-DOPA that rearranges non-enzymatically to betalamic acid. Can also catalyze the formation of muscaflavin...
TMPY-02525	RGMA Protein, Human, Recombinant (His)	Human	HEK293
	RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPK-00258	Latent TGF beta 3 Protein, Human, Recombinant (His)	Human	HEK293
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen...
TMPK-00259	Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen...
TMPJ-01161	CTGF/CCN2 Protein, Human, Recombinant	Human	Human Cells
	CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cel...
TMPY-04671	MCP-5 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa...
TMPJ-01162	CTGF/CCN2 Protein, Human, Recombinant (hFc)	Human	Human Cells
	CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cel...
TMPJ-01369	DPT Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Dermatopontin is a widely expressed noncollagenous protein component of the extracellular matrix. It is a 22 kDa molecule that is tyrosine sulfated but not glycosylated. Dermatopontin is down regulated in fibrotic growth...
TMPY-01846	Activin A Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...
TMPY-01190	INHBB Protein, Human, Recombinant (His)	Human	HEK293
	Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. The activin and inhibin protein complexes are both dimeric in structure, and, in each complex, the two ...