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Foscarnet sodium (Phosphonoformate) is an antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV.

Ascaridole (NSC-406266) acts as an anthelmintic compound that repels parasitic helminths (worms) in humans and plants and has weak antimalarial activity.

Descarbamoyl cefuroxime is also an intermediate in the synthesis of cephalosporin antibiotics. Decarbamyl cefuroxime is a degradation product of cefuroxime.

Cascaroside A is a useful organic compound for research related to life sciences and the catalog number is T124690.

Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.

Muscarinic acetylcholine receptor agonist

Muscarine is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.

Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.

Scaritoxin is a potent toxic substance isolated from poisonous fish.

Liriope muscari baily saponins C has an anti-thrombotic activity due to down-regulation of the increased mRNA expression levels of TF and IL-6.

Saponin C from Liriope muscari can be extracted from Liriope muscari, family Liliaceae, has antithrombotic activity and induces autophagy.

(±)-Muscarine chloride is the racemate of Muscarine chloride, a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].

Muscarinic toxin 7 (MT7) is a peptide exhibiting selective, noncompetitive antagonistic activity at the muscarinic M1 receptor [1].

Muscarinic toxin 3 (MT3), a potent non-competitive antagonist of mAChR and adrenoceptors, exhibits pIC50 values of 6.71 for M1, 8.79 for M4, 8.86 for α1A, 7.57 for α1B, 8.13 for α1D, 8.49 for α2A, <6.5 for α2B, and 7.29 for α2C receptors. MT3 notably demonstrates significant adrenoceptor activity [1].

Compound 40 is a selective M1 M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].

Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].

Descarbonyl-lacosamide is a potential impurity in commercial lacosamide preparations. It is a degradation product that forms under acidic conditions.

Compound 42, also known as M1 M2 M4 muscarinic agonist 1, is a muscarinic M4 M1 M2 agonist exhibiting EC50 values of 6.5, 26, and 210 nM for M4, M1, and M2 respectively. This compound is utilized in research focused on mental disorders, including schizophrenia and delusion [1].

Muscarinic agonist 3 (compound 45) is a muscarinic mAChR M1 M2 M4 agonist with EC50 values of 3.2 nM, 32 nM, and 1.7 nM, respectively [1].

Compound 44, identified as an M1 M4 muscarinic agonist, exhibits potent activity with EC50 values of 31 nM at M1 and 9.3 nM at M4 mAChRs, respectively [1].

Aganepag, a potent Prostanoid EP2 receptor agonist, exhibits remarkable selectivity with an EC50 of 0.19 nM, demonstrating no activity at the EP4 receptor. Its applications are primarily in the fields of wound healing, scar reduction, scar prevention, and the treatment and prevention of wrinkles.

Trans-Tranilast is an antiallergic drug developed by Kissei Pharmaceuticals. It was approved in 1982 for use in Japan and South Korea for bronchial asthma. Indications for keloid and hypertrophic scar were added in 1993. It has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

TGN-020 is an inhibitor of Aquaporin 4 (AQP4, IC50: 3.1 μM), the most abundant water channel in the brain.

D-Glucosamine-6-sulfate is a naturally occurring glycosaminoglycan. It activates the glmS ribozyme from B. subtilis, a Gram-positive bacterium, when used at a concentration of 200 μM. It has been used to form polyvalent dendrimer conjugates that inhibit angiogenesis and endothelial cell proliferation induced by FGF-2 in vitro and prevent scar tissue formation in a rabbit model of glaucoma surgery.