palmitoyltransferase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T78569	CPT2	Carnitine palmitoyltransferase 2	Apoptosis
	Carnitine palmitoyltransferase 2 (CPT2), an enzyme involved in fatty acid oxidation, serves as a prognostic biomarker for colorectal cancer (CRC). Overexpression of CPT2 activates phosphorylated p53, enhancing its expres...		Apoptosis
T4535	Etomoxir sodium salt	(R)-Etomoxir sodium salt,Na salt,Etomoxir	Apoptosis , Others
	Etomoxir sodium salt ((R)-Etomoxir sodium salt) is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that blocks fatty acid synthesis. Etomoxir sodium salt has antitumor activity.		Apoptosis , Others
T26308	Lipoxamycin hemisulfate	Lipoxamycin, sulfate (2:1),U-26146D,U26146D,U 26146D,Lipoxamycin	Antifungal
	Lipoxamycin hemisulfate (Lipoxamycin) is an inhibitor of serine palmitoyltransferase (IC50 = 21 nM) with antifungal activity.		Antifungal
T11978	McN3716	NSC359682,Methyl palmoxirate	Mitochondrial Metabolism , CPT
	McN3716 is a carnitine palmitoyltransferase I (CPT-1) inhibitor for the study of metabolic diseases.		Mitochondrial Metabolism , CPT
T35364	2-Bromohexadecanoic acid	2-BP,2-bromopalmitate,2-Bromohexadecanoic acid	Others
	2-Bromohexadecanoic acid (2-BP) is a non-metabolizable palmitate analogue, which can be used as palmitoylation inhibitor. 2-BP directly and irreversibly inhibits the palmitoyltransferase activity of all DHHC (Asp-His-His...		Others
T4785	Oxfenicine	4-Hydroxy-L-phenylglycine	Others
	Oxfenicine (4-Hydroxy-L-phenylglycine) is a carnitine palmitoyltransferase-1 inhibitor. Oxfenicine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistanc...		Others
T4535L	Etomoxir	(R)-(+)-Etomoxir	Antioxidant , CPT
	Etomoxir is a carnitine palmitoyltransferase 1a (CPT-1a) inhibitor that inhibits fatty acid oxidation by inhibiting CPT-1a and inhibits palmitate oxidation in humans, rats, and guinea pigs. Etomoxir has an inhibitory eff...		Antioxidant , CPT
T36831	9-Oxononanoic Acid	9-ONA	Phospholipase , CPT
	9-Oxononanoic Acid is an oxidized fatty acid, formed by the autoxidation of linoleic acid, which enhances phospholipase A2 (PLA2) activity and increases the production of thromboxane B2 in isolated human plasma.9-Oxonona...		Phospholipase , CPT
T26308L	Lipoxamycin HCl	Lipoxamycin HCl（11075-87-9 Free base）
	Lipoxamycin HCl is a potent serine palmitoyltransferase inhibitor with antifungal activity and inhibits serine palmitoyltransferase activity.
T68445	Clomoxir
	Clomoxir is a carnitine palmitoyltransferase I inhibitor that was under development as an antiarrhythmic and antidiabetic.
T38685	C12-Sphingosine	C12-Sphingosine
	C12-Sphingosine is a short-chain homologue of Sphingosine. It effectively inhibits the activity of serine palmitoyltransferase in primary cultured cerebellar cells.
T68618	S-(-)-Etomoxir
	S-(-)-Etomoxir is an inhibitor of carnitine palmitoyltransferase A (CPT1) -- a molecule required for the oxidation of long-chain acyl CoA esters.
T37245	Palmitoyl-D-carnitine (chloride)
	Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine , and the D enantiomer of palmitoyl-DL-carnitine . It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palm...
T68196	Aminocarnitine
	Aminocarnitine is an inhibitor of fatty acid oxidation that acts as a hypoglycemic and antiketogenic compound. It alters lipidic metabolism by inhibiting carnitine acetyltransferase (CAT) and carnitine palmitoyltransfera...
T83767	4-Hydroxyphenylglyoxylic Acid	UK 22486
	4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1). It effectively inhibits CPT1 in isolated rat liver mitochondria at conc...
T73829	Malonyl CoA
	Malonyl CoA serves as a substrate in fatty acid biosynthesis while inhibiting fatty acid oxidation. It also acts as a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1 [1] [2].
T71554	ARN 14494
	ARN 14494 is a potent serine palmitoyltransferase inhibitor (SPT; IC50 = 27.3 nM). ARN 14494 inhibits synthesis of long chain ceramides and dihydroceramides in an in vitro model of Alzheimer's diease. The compound preven...
T38214	1-Deoxysphingosine (m18:1(4E))	1-Deoxysphingosine (m18:1(4E))
	1-Deoxysphingosine (m18:1(4E)) is an atypical sphingolipid that contains a double bond at the 4E native position and is formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine durin...
T16165	Myriocin	ISP-I,Thermozymocidin	HCV Protease , Antifungal
	Myriocin (Thermozymocidin), a metabolite derived from Myriococcum albomyces, is a serine-palmitoyltransferase (SPT) inhibitor with potential antitumour, anticancer, and antiparasitic activities.Myriocin inhibits tumour g...		HCV Protease , Antifungal
T38284	C24 dihydro 1-Deoxyceramide (m18:0/24:0)	C24 dihydro 1-Deoxyceramide (m18:0/24:0)
	C24 dihydro 1-Deoxyceramide (m18:0/24:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...