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Search Results for " leptin "

Compounds

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T39418	Leptin (93-105), human
	Leptin (93-105), human, refers to the peptide fragment consisting of amino acids 93 to 105 from the human leptin protein. Leptin is a peptide hormone comprising 167 amino acids, predominantly synthesized by adipocytes. I...
TP1356	Leptin (22-56), human
	Leptin(22-56),human is a peptide fragment of Leptin, which ACTS through a variety of subtypes of Ob-Rs.
T76221	Leptin (116-130)
	Leptin (116-130), a bioactive fragment of leptin, enhances synaptic plasticity in the hippocampus by promoting AMPA receptor trafficking to synapses. It preserves hippocampal synapse integrity and prevents neuronal cell ...
T7704	KY-226		Phosphatase
	KY-226 is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B)(IC50: 0.25 μM,)		Phosphatase
T2008	LY294002	LY 294002,NSC 697286,SF 1101	Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
	LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 ...		Apoptosis , DNA-PK , Casein Kinase , PI3K , Autophagy
T4079	LY-294002 hydrochloride	SF 1101,LY 294002,NSC 697286	PI3K
	LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...		PI3K
T32645	Leptine I, from Solanum chacoense	Leptine I
	Leptine I, from Solanum chacoense is a glycoalkaloid in the foliage of the wild potato species Solanum chacoense.
TP1305	LEP(116-130)(mouse)		Others
	Leptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake an...		Others
TP1305L	LEP(116-130)(mouse)TFA(258276-95-8 free base)		Complement System
	LEP(116-130)(mouse) is a synthetic leptin peptide fragment.		Complement System
T23557	Talibegron hydrochloride	ZD2079 hydrochloride,ZD 2079	Adrenergic Receptor
	Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. In...		Adrenergic Receptor
T81628	OB3
	OB3, a leptin derivative, exhibits greater efficacy than leptin in diminishing obesity and diabetes in mouse models. Additionally, OB3 mitigates leptin-associated inflammation and proliferation in hepatocellular carcinom...
T78020	Allo-aca
	Allo-aca, a leptin peptidomimetic, selectively inhibits leptin receptor activity as a potent antagonist peptide, effectively disrupting leptin signaling in various in vitro and in vivo models [1] [2].
T83145	Allo-aca TFA
	Allo-aca TFA, a potent and specific leptin receptor antagonist peptide, inhibits leptin signaling and function across various in vitro and in vivo models [1] [2].
T75899	CART(55-102)(human) TFA
	CART(55-102)(human) TFA, a human satiety factor, exhibits strong appetite-suppressing activity. It is closely linked with leptin and neuropeptide Y [1] [2].
TP2215	Agouti-related Protein (AGRP) (25-82), human		Others
	Agouti-related peptide (AgRP) is a neuropeptide produced in the brain by the AgRP/NPY neuron. It is only synthesized in NPY containing cell bodies located in the ventromedial part of the arcuate nucleus in the hypothalam...		Others
T72745	Acipimox sodium	K-9321 sodium
	Acipimox (K-9321) sodium, a nicotinic acid analogue, functions as an antilipolytic agent by stimulating leptin release, inhibiting lipolysis, and reducing systemic free fatty acids (FFAs) levels, thereby enhancing insuli...
T71559	Melanotan II acetate
	Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases...
T75900	CART(55-102)(rat) TFA
	CART(55-102)(rat) TFA, a rat-derived satiety factor, exhibits potent appetite-suppressing properties. This compound is intricately linked to both leptin and neuropeptide Y, playing a crucial role in the regulation of hun...
T76366	CART (55-76), rat
	CART (55-76), rat, a neuropeptide comprising residues 55-76 of the CART peptide and serving as the N-terminal fragments of CART (55-102), functions as a rat satiety factor. It demonstrates potent appetite-suppressing act...
T76365	CART (1-39), Human, Rat
	CART (1-39), Human, Rat is a neuropeptide comprising the first 39 residues of the CART peptide. This compound serves as a rat satiety factor, possessing significant appetite-suppressing effects, and demonstrates a close ...
T36106	Coumermycin A1
	Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria. Coumermycin A1-induced-JAK2 signal activation increases the mRNA level of SCOS2, but reducea...
T83906	Tirzepatide sodium	LY3298176
	Tirzepatide acts as an agonist for both the glucagon-like peptide 1 receptor (GLP-1R) and G protein-coupled receptor 119 (GPR119), effectively inducing cAMP production in HEK293 cells that express either human GLP-1R or ...

Compounds

Leptin (93-105), human

T39418

Synonym:

Target:

Leptin (22-56), human

Synonym: LY 294002,NSC 697286,SF 1101

Target: Apoptosis, DNA-PK, Casein Kinase, PI3K, Autophagy

LY-294002 hydrochloride

T4079

Synonym: SF 1101,LY 294002,NSC 697286

Target: PI3K

Leptine I, from Solanum chacoense

LEP(116-130)(mouse)TFA(258276-95-8 free base)

TP1305L

Synonym:

Target: Complement System

Talibegron hydrochloride

T23557

Synonym: ZD2079 hydrochloride,ZD 2079

Target: Adrenergic Receptor

CART(55-102)(human) TFA

Synonym: K-9321 sodium

CART(55-102)(rat) TFA

CART (1-39), Human, Rat

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-00875	Leptin Protein, Human, Recombinant	Human	E. coli
	Leptin Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is A4D0Y8.
TMPY-01725	Leptin Receptor Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Leptin Receptor Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is P48357-1.
TMPY-06375	Leptin Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	Leptin Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.33 kDa and the accession number is P41160.
TMPJ-00052	Leptin Protein, Mouse, Recombinant	Mouse	E. coli
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. Animal models have ...
TMPK-00050	Leptin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita...
TMPJ-00606	Leptin Protein, Carassius auratus, Recombinant (His)	Carassius auratus	P. pastoris (Yeast)
	Leptin is a hormone secreted from white adipocytes and plays important role in the regulation of food intake and energy balance. Leptin functions via signaling pathways involving OB-R in hypothalamus. In mammals, leptin ...
TMPY-00874	Leptin Receptor Protein, Human, Recombinant (His & hFc)	Human	HEK293 Cells
	Leptin Receptor Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 121.4 kDa and the accession number is P48357-1.
TMPJ-00411	LEPR Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LEPR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 150-180 KDa and the accession number is P48357.
TMPJ-00976	LEPR Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-10His tag. The predicted molecular weight is 120-150 KDa and the accession number is P48356.
TMPJ-00977	LEPR Protein, Mouse, Recombinant (mFc)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 130-190 KDa and the accession number is P48356.
TMPJ-00975	LEPR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	LEPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 130-190 KDa and the accession number is P48356.
TMPJ-01473	BMP-7 Protein, Human, Recombinant	Human	HEK293 Cells
	Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPJ-01061	Nucleobindin-2 Protein, Human, Recombinant	Human	E. coli
	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin2 (NUCB2). Nesfatin-1 is a neuropeptide produced in the hypothalamus of mammals. It participates in the regulat...
TMPY-00286	Neuropeptide Y Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NPY (Neuropeptide Y) is a Protein Coding gene. This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress ...
TMPJ-00286	ANGPTL3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Angiopoietin-like 3 (ANGPTL3) is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C-terminal fibrinogen-like domain. ANGPTL3 ...
TMPY-02194	SOCS3 Protein, Human, Recombinant (His & Trx)	Human	E. coli
	Suppressor of cytokine signaling 3, also known as SOCS-3, Cytokine-inducible SH2 protein 3, CIS-3, STAT-induced STAT inhibitor 3, SOCS3 and CIS3, is a protein which is widely expressed with high expression in heart, plac...
TMPH-02274	JAK2 Protein, Human, Recombinant (His)	Human	E. coli
	Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cyto...