hyaluronic acid

Hyaluronic acid (hyaluronan) is a glucosaminoglycan consisting of D-glucuronic acid and N-acetyl-D-glucosamine disaccharide units that is a component of connective tissue, skin, vitreous humour, umbilical cord, synovial fluid and the capsule of certain microorganisms contributing to adhesion, elasticity, and viscosity of extracellular substances.

Hyaluronic acid tetrasaccharide, a naturally occurring polysaccharide found in the extracellular matrix of connective tissue, serves as a substrate in enzymatic assays to characterize the activity of hyaluronidases and other hyaluronic acid-degrading enzymes.

Hyaluronic acid sodium (Sodium Hyaluronate) is an anionic, nonsulfated glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is unique among glycosaminoglycans in that it is nonsulfated, forms in the plasma membrane instead of the Golgi, and can be very large, with its molecular weight often reaching the millions. One of the chief components of the extracellular matrix, hyaluronic acid contributes significantly to cell proliferation and migration, and may also be involved in the progression of some malignant tumors.

Hyaluronic acid sodium (MW 100 kDa) is a low molecule of sodium hyaluronate that penetrates into the dermis and promotes skin metabolism.

Hyaluronic acid sodium (MW 10 kDa) is a low molecular sodium hyaluronate with stabilizing and restorative properties, which can slow down skin aging and promote the proliferation and differentiation of epidermal cells.

Hyaluronic acid sodium (MW 20 kDa) is a low molecule of sodium hyaluronate that penetrates into the dermis and promotes skin metabolism.

Hyaluronic acid sodium (MW 40 kDa) is a low molecule of sodium hyaluronate that penetrates into the dermis and promotes skin metabolism.

Hyaluronic acid sodium (MW 200 kDa) is a medium molecule sodium hyaluronate that penetrates into the dermis and stimulates skin metabolism.

Hyaluronic acid sodium (MW 300 kDa) is a medium molecule sodium hyaluronate that penetrates into the dermis and stimulates skin metabolism.

Hyaluronic Acid Methacryloyl (HAMA) with a molecular weight of 150 kDa is a biocompatible methacrylated derivative of hyaluronic acid. HAMA is utilized as an ink for 3D printing hydrogels, exhibiting rapid photoreactive responses, quick gelation speeds, and stable hydrogel properties. Under ultraviolet light exposure, HAMA efficiently induces gelation in conjunction with phenyl-2,4,6-trimethylbenzoylphosphinate (LAP). The integration of HAMA with tissue-specific extracellular matrix (ECM) materials, such as pancreatic ECM (pECM), is poised to become a vital source material for organ-like tissue cultivation.

Hyaluronic acid sodium (MW 2,000,000 kDa) is a high molecular hyaluronic acid sodium, with moisturizing effect, can form a thin layer on the surface of the skin, can slow down the evaporation of water from the surface of the skin.

Hyaluronic acidmethacryloyl (MW 10000) (HAMA (MW 10000)) is a derivative of Hyaluronic acid. Materials based on Hyaluronic acidmethacryloyl have been utilized in various biomedical research fields.

Hyaluronic acidmethacryloyl (MW 50000) (HAMA (MW 50000)) is a derivative of Hyaluronic acid. Materials based on Hyaluronic acidmethacryloyl are utilized in various biomedical research fields.

Hyaluronic acid Methacryloyl (MW 400 kDa) is a methacrylated form of hyaluronic acid that exhibits biocompatibility. It functions as a 3D printing hydrogel ink, characterized by rapid photosensitivity, quick gelation speed, and stable hydrogel properties. Upon UV exposure, it can rapidly initiate gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP). Additionally, when combined with tissue-specific extracellular matrix (ECM) materials, such as pancreatic extracellular matrix (pECM), Hyaluronic acid Methacryloyl (MW 400 kDa) serves as a crucial source material for organoid culture.

Hyaluronic acid methacryloyl (MW 300000) (HAMA (MW 300000)) is a natural extracellular matrix (ECM) with anti-inflammatory properties that promotes cell adhesion and proliferation. This compound is extensively used in tissue engineering and regenerative medicine. Upon exposure to ultraviolet light, Hyaluronic acid methacryloyl (MW 300000) (HAMA (MW 300000)) quickly forms a hydrogel.

4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.

Hyaluronidase (Hyaluronate 4-glycanohydrolase), a naturally occurring enzyme, depolymerizes hyaluronic acid through glycosidic bond cleavage and is utilized in ophthalmic surgery.

HA-CD44 interaction inhibitor 1 is an anti-tumor agent, which is a hyaluronic acid inhibitor targeting CD44. HA-CD44 interaction inhibitor 1 can inhibit MDA-MB-231 cells with an EC50 of 1.77 μM.

HA-CD44 interaction inhibitor 3 (compound 5d) is an inhibitor of the Hyaluronic acid (HA)-CD44 interaction. It has inhibitory effects on MDA-MB-231 (CD44++) cells and MCF-7 (CD44--) cells with EC50 values of 4.24 μM and 14.74 μM, respectively. HA-CD44 interaction inhibitor 3 is applicable to cancer research.

2-Ethylhexyl (E)-3-(4-(methoxy-d3)phenyl)acrylate is the deuterated form of Octinoxate. Octinoxate (Octyl methoxycinnamate) acts as an agonist of thyroid hormone receptors, leading to a reduction in triiodothyronine (T3) and thyroxine (T4) levels, as well as the transcription levels of type II deiodinase (deio2) related genes in Japanese Medaka. Commonly used as a safe ultraviolet (UV) filter in aquatic environments, Octinoxate inhibits CYP1A1 and CYP1B1, and influences hyaluronic acid (HA) metabolism in human keratinocytes through a PI3K pathway-dependent manner. It also exhibits both anti-estrogenic and anti-androgenic effects in vitro and in vivo.

Dextranomer, for treatment of burns; consists of three-dimensional network of dextran polymers cross-linked by epichlorohydrin; dextranomer based implants usedas a bulking agent for endoscopic treatment of pediatric structural incontinence; ingredient of

β-D-Glucosamine pentaacetate is an N-acetylglucosamine derivative that has been shown to promote hyaluronic acid production.

Palmitoyl tetrapeptide-7 is a cosmeceutical peptide that stimulates type I collagen, fibronectin, and hyaluronic acid production in skin.1Formulations containing palmitoyl tetrapeptide-7 have been used in the treatment of photoaging, dark circles, and undereye puffiness. 1.Bucay, V.W., and Day, D.Adjunctive skin care of the brow and periorbital regionClin. Plast. Surg.40(1)225-236(2013)

Guluronic acid (G2013) is an organic building block found in hyaluronic acid. It functions as a nonsteroidal anti-inflammatory agent and displays a beneficial anti-inflammatory effect.