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Results for "

cma

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    13
    TargetMol | Inhibitors_Agonists
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    2
    TargetMol | Peptide_Products
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Inhibitors_Agonists
Cridanimod
CMA, XBIO-101, 10-carboxymethyl-9-acridanone
T531738609-97-1
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1 IRF3 route.
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PACMA 31
T412771401089-31-3In house
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
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Epacmarstobart
GS-0189, FSI-189
T824612518200-89-8
Epacmarstobart (FSI-189; GS-0189) is a chimeric humanized IgG1κ antibody targeting mouse Signal Regulatory Protein Alpha (SIRPA).
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BCMA72-80
TP18062293841-58-2
BCMA72-80 is an HLA-A2-specific B-cell maturation antigen (BCMA) peptide with a strong affinity for HLA-A2, and is employed in research on multiple myeloma or other tumors expressing B-cell maturation antigen.
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BCMA72-80 acetate(2293841-58-2 free base)
TP1806L
BCMA72-80 acetate is a HLA-A2 specific B cell maturation antigen (BCMA) peptide. It is used to study multiple myeloma and tumors, which expresses B cell maturation antigen.
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AR7
T395580306-38-3
AR7 is a retinoic acid receptor α (RARα) antagonist.
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QX77
T46631798331-92-6
QX77 is a chaperone-mediated autophagy (CMA) activator.
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CA77.1
T90622412270-22-3
CA77.1(CA) is a novel chaperon-mediated autophagy (CMA) activator for the treatment of Alzheimer's disease (AD).
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STING IN 42
T2040122925028-24-4
STING IN 42 has STING inhibitory activity and can block palmitoylation of STING proteins and downstream STING signaling. STING IN 42 has good pharmacokinetic properties and can effectively inhibit STING mediated inflammation in mice treated with 10-carboxymethyl-9-acridone (CMA) and Trex1- - mice orally.
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7-10 days
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FDW028
FDW 028
T778092768426-49-7
FDW028 is a selective and potent fucosyltransferase 8 (FUT8) inhibitor with anti-tumor activity that drives B7-H3 lysosomal degradation via defucosylation and CMA pathways. FUT8 can be used to study metastatic colorectal cancer (mCRC).
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Gemtuzumab
CMA-676, CDP-771
T9901A-0032924764-21-4
Gemtuzumab(CMA-676) is a monoclonal antibody directed against the CD33 antigen and consists of a recombinant humanized IgG4 antibody.Gemtuzumab can be used to synthesize Gemtuzumab ozogamicin, an antibody coupled compound (ADC) Gemtuzumab is used in the study of acute myeloid leukemia.
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I2959
TCL-00041106797-53-9
I2959 is extensively used as a photoinitiator for photocrosslinking hydrogels and is particularly utilized in combination with CMA hydrogels as bioink for bio 3D printing applications. Furthermore, I2959 is known for its high radical generation efficiency and exhibits cytotoxicity to rapidly dividing cell lines.
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7-10 days
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Epimedokoreanin B
TN3972161068-53-7
Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-inflammatory and antibacterial activities, and may have scavenging activity against DPPH radicals, inhibiting the proliferation of MCF-7 and HepG2 in a dose-dependent manner. Epimedokoreanin B also exhibits anti-inflammatory and antibacterial activity, with DPPH radical scavenging activity, and inhibits the proliferation of MCF-7 and HepG2 in a dose-dependent manner.Epimedokoreanin B significantly inhibits the formation of N (α)-(carboxymethyl)lysine (CML) and N (Ï)-(carboxymethyl)arginine (CMA), and prevents clinical complications of diabetes mellitus through the inhibition of advanced glycation end-products (AGEs).
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