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    TargetMol | Inhibitors_Agonists
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Retinoic acid
Vitamin A acid, Tretinoin, ATRA, all-trans-Retinoic acid
T1051302-79-4
Retinoic acid (Tretinoin), a metabolite of vitamin A, is a natural agonist of the retinoic acid receptor RAR and inhibits RARα β γ (IC50=14 nM). Retinoic acid induces cellular differentiation, reduces cellular proliferation, and inhibits tumorigenesis.
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Veratramine
NSC17821, NSC23880
T336460-70-8
Veratramine (NSC-23880)(NSC-17821; NSC-23880) is a potent signal transduction inhibitor for treating tumors.
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Veratraldehyde
3,4-Dimethoxybenzaldehyde
T5657120-14-9
Veratraldehyde (3,4-Dimethoxybenzaldehyde) has antifungal activity .It is found in Cymbopogon javanensis.
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Atraric acid
TCS13724707-47-5
Atraric acid derivatives as a new chemical lead structure for novel therapeutic compounds as AR antagonists, that can be used for prophylaxis or treatment of prostatic diseases. It inhibits PTP1B activity in a dose-dependent manner with IC50 values of 51.5 uM, suggest that atraric acid has potential to treat diabetes.
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Atractylenolide I
T5S016773069-13-3
1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the res
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Atractylenolide II
2-Atractylenolide, Asterolide
T5S016873069-14-4
1. Atractylenolide II (2-Atractylenolide) has antimelanoma effect by inhibiting STAT3 signalling. 2. Atractylenolide II has cytotoxic apoptotic effects may via p38 activation , ERK and Akt inactivation, p53 dependent.
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Carboxyatractyloside
C 4992, Gummiferin
T817077228-71-8
Carboxyatractyloside (Carboxyatractyloside tripotassium salt) is a natural product. It acts as an inhibitor of ADP ATP carrier, inhibits mitochondrial ADP ATP transport.
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Cynatratoside B
T12383297399-97-8
Cynatratoside B is a useful organic compound for research related to life sciences. The catalog number is T123832 and the CAS number is 97399-97-8.
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Atractylenolide IV
T125815147396-00-7
Atractylenolide IV is a useful organic compound for research related to life sciences. The catalog number is T125815 and the CAS number is 147396-00-7.
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Atractysucrose IIIa
T1264671053636-75-1
Atractysucrose IIIa is a useful organic compound for research related to life sciences. The catalog number is T126467 and the CAS number is 1053636-75-1.
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Satratoxin H
Satratoxin-H
T3453653126-64-0
Satratoxin H is an air- and food-borne mycotoxin, which has been implicated in human health damage.
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Atractylodin
Atractydin
T366655290-63-6
Atractylodin (Atractydin) has high lipase inhibitory activity (IC5:39.12 μM); Atractylodin possesses strong repellency activities against T. castaneum adults (LD50: 1.83 μg cm). The repellency of Atractylodin (0.63 μg cm) can achieve >90%.
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Atractyloside A
T3791126054-77-1
Atractyloside is a glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of adenine nucleotide translocase.
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Atractylenolide III
ICodonolactone, 8β-Hydroxyasterolide
T390273030-71-4
Atractylenolide III (ICodonolactone) may have therapeutic potential in treating homocysteine-mediated cognitive impairment and neuronal injury. Atractylenolide III is a potential candidate for the treatment of human lung carcinoma by inducing the release of cytochrome c, upregulating the expression of Bax and translocating apoptosis-inducing factor.
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Atractyloside potassium salt
Atractyloside Dipotassium Salt
T3S0156102130-43-8
1. Atractyloside potassium salt (Atractyloside Dipotassium Salt) inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane.
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Atractylone
Atractylon
T3S01656989-21-5
Atractylone (Atractylon) has the functions of protecting liver, lowering blood sugar, antibacterial, anti-tumor and anti-virus.
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Cynatratoside D
T8263497399-99-0
Cynatratoside D, an oligoglycoside, has been isolated from the root of the plant Cynanchum atratum Bunge (Asclepiadaceae) [1].
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Atranorin
TN1413479-20-9
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotective effects on cells under oxidative
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8beta-Methoxyatractylenolide I
TN3304193694-24-5
8beta-Methoxyatractylenolide I is a natural product from Atractylodes macrocephala.
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Acetylatractylodinol
Tractylodinol acetate
TN334061582-39-6
Acetylatractylodinol (Tractylodinol acetate) is a natural product isolated from Atractylodes lancea, possesses antioxidant activity.
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Atractylochromene
TN3468203443-33-8
Atractylochromene is an inhibitor of β-catenin dependent Wnt pathway, it may be a potential chemotherapeutic agent for the prevention and treatment of human colon cancer.
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Cynatratoside A
TN374797399-96-7
Cynatratoside A and Cynanversicoside C are therefore potential candidate drugs for use against Ichthyophthirius multifiliis.
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Biatractylolide
(+)-Biatractylolide
TN6469182426-37-5
Biatractylolide is a natural product that can be used for research related to the life sciences.
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23-O-β-D-Glucopyranosyl-20-isoveratramine
TN7597148440-62-4
23-O-β-D-Glucopyranosyl-20-isoveratramine, extracted from nettles, shows promise as an anti-allergic agent. Nettle extract contains a range of COX-1, COX-2, 5-lipoxygenase, and trypsin-like inhibitors, as well as H1 antagonists. These compounds collectively help mitigate symptoms of seasonal allergies, allergic rhinitis, and other inflammatory diseases, offering both treatment and preventive benefits [1].
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