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Results for "

PGE synthase

" in TargetMol Product Catalog
  • Inhibitor Products
    21
    TargetMol | Activity
  • Natural Products
    4
    TargetMol | inventory
(S)-Flurbiprofen
T5843L51543-39-6
Esflurbiprofen is an inhibitor of COX-1 and COX-2.
  • $29
In Stock
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QTY
Oxidopamine hydrochloride
T1235228094-15-7
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.
  • $39
In Stock
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QTY
TargetMol | Citations Cited
ETHYL CAFFEATE
T5681102-37-4
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro. Furthermore, Ethyl Caffeate intensely blocked the transcriptional expression in interferon-γ-related signaling, including IFN-γ, T-bet, STAT1, and STAT4.
  • $41
In Stock
Size
QTY
TargetMol | Citations Cited
Oxidopamine hydrobromide
T12352L636-00-0
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.
  • $56
In Stock
Size
QTY
TargetMol | Citations Cited
HPGDS inhibitor 2
T79482101626-26-8
HPGDS inhibitor 2 (GSK-2894631A) is a potent, selective hematopoietic prostaglandin D synthase (h-pgds) inhibitor, IC50 = 9.9 nm.
  • $88
In Stock
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QTY
TargetMol | Inhibitor Sale
PGS-IN-1
T10098102271-49-8
PGS-IN-1 (KME-4) is a potent inhibitor of prostaglandin synthetase (PGS, IC50: 0.28 μM) and 5-lipoxygenase (IC50: 1.05 μM).
  • $44
In Stock
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QTY
TargetMol | Inhibitor Sale
hPGDS-IN-1
T26811234708-04-3
hPGDS-IN-1 is a hPGDS inhibitor.
  • $73
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Limaprost
T1575774397-12-9
Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost (17α,20-dimethyl-δ2-PGE1) can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.
  • $198
35 days
Size
QTY
TargetMol | Inhibitor Sale
1a,1b-dihomo Prostaglandin E2
T3604526198-80-1
1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
  • $296
35 days
Size
QTY
AT-56
T1866162640-98-4
AT56, a specific inhibitor of prostaglandin D2 synthase enzymatic activity, blunted adipogenic aldosterone effects.
  • $33
In Stock
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QTY
HPGDS inhibitor 1
T18041033836-12-2
HPGDS inhibitor 1 is a novel and selective inhibitor for Hematopoietic Prostaglandin D Synthase (HPGDS) with an IC50 Value of 0.7 nM.
  • $88
In Stock
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TargetMol | Inhibitor Sale
Benzydamine hydrochloride
T0726132-69-4
Benzydamine hydrochloride (AF864), a locally-acting nonsteroidal anti-inflammatory drug, has local anaesthetic and analgesic properties.
  • $33
In Stock
Size
QTY
Zomepirac sodium salt
T026464092-48-4
Zomepirac sodium salt (McN-2783-21-98) is a prostaglandin synthetase inhibitor.
  • $31
In Stock
Size
QTY
CAY10526
T23861938069-71-7
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
  • $57
In Stock
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Bismuth Subsalicylate
T042414882-18-9
Bismuth Subsalicylate (Bismuth subsalicylat) is the active ingredient in the popular medication Pepto-Bismol that is used to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
  • $48
In Stock
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QTY
Pranoprofen
T015952549-17-4
Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.
  • $42
In Stock
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QTY
CAFESTOL
T5727469-83-0
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.
  • $32
In Stock
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QTY
Sinensetin
T4S02272306-27-6
Sinensetin (Pedalitin permethyl ether) is a methylated flavone found in certain citrus fruits. pocess potent antiangiogenesis and anti-inflammatory, sinensetin enhances adipogenesis and lipolysis.
  • $57
In Stock
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AF3442
T68334924636-93-1
AF3442 is a potent and selective mPGES-1 inhibitor (microsomal prostaglandin (PG) E synthase-1). AF3442 caused a concentration-dependent inhibition of PGE(2) in human recombinant mPGES-1 with an IC(50) of 0.06microM. AF3442 is a selective mPGES-1 inhibitor which reduced monocyte PGE(2) generation also in the presence of plasma proteins. Pharmacological inhibition of mPGES-1 did not translate into redirection of PGH(2) metabolism towards other terminal PG synthases in monocytes. The functional relevance of this observation deserves to be investigated in vivo.
  • $1,520
6-8 weeks
Size
QTY
Suprofen
T668740828-46-4
Suprofen (Suprol) is an IBUPROFEN-type anti-inflammatory analgesic and antipyretic. It inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.
  • $35
In Stock
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Dehydroevodiamine
T2S233567909-49-3
Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant, inhibition of nitric oxide production and cerebral blood flow enhancing activities.
  • $35
In Stock
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