nkg2d — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T81669	NKG2D-IN-2
	NKG2D-IN-2 (compound 47) is an inhibitor of the natural killer group 2D receptor (NKG2D), demonstrating half-maximal inhibitory concentrations (IC50s) of 0.1 µM for NKG2D/MICA and 0.2 µM for ULBP6 in time-resolved fluore...
T81670	NKG2D-IN-1
	NKG2D-IN-1, also known as compound 21, is an inhibitor of the natural killer group 2D receptor (NKG2D) exhibiting inhibitory concentration 50 (IC50) values of 0.3 µM in NKG2D/MICA TR-FRET assays and 0.7 µM in ULBP6 TR-FR...
T77404	Tesnatilimab	IPH-23XX,JNJ-64304500,JNJ 4500	Others
	Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D. Tesnatilimab has potential immunomodulatory and anti-inflammatory activity and can be used to study active u...

Recombinant Proteins

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Expression System：

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Cat No.	Product Name	Species	Expression System
TMPY-05414	NKG2D/CD314 Protein, Mouse, Recombinant (hFc)	Mouse	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (hFc) is expressed in Baculovirus insect cells with hFc tag. The predicted molecular weight is 44.9 kDa and the accession number is O54709-2.
TMPY-00467	NKG2D/CD314 Protein, Human, Recombinant (hFc)	Human	CHO Cells
	NKG2D/CD314 Protein, Human, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 46.5 kDa and the accession number is A0A024RAP8.
TMPY-03376	NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His)	Rhesus	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Rhesus, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.3 kDa and the accession number is P61252.
TMPY-03256	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His)	Human	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Human, Recombinant (aa 78-216, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is P26718-1.
TMPK-00107	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate l...
TMPK-00106	NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate l...
TMPK-00105	NKG2D/CD314 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate l...
TMPK-00108	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate l...
TMPY-06827	NKG2D/CD314 Protein, Human, Recombinant (mFc)	Human	Baculovirus Insect Cells
	NKG2D/CD314 Protein, Human, Recombinant (mFc) is expressed in Baculovirus insect cells with mFc tag. The predicted molecular weight is 41.83 kDa and the accession number is P26718-1.
TMPJ-00097	NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)	Cynomolgus	HEK293 Cells
	NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P61252.
TMPJ-00122	NKG2D/CD314 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	NKG2D/CD314 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 20-30 KDa and the accession number is O54709.
TMPK-00136	ULBP-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPK-00137	ULBP-2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	ULBP2 expression was however linked to expression of mature CD57() NK cells. In particular, expression of ULBP2 was strongest on those NK cells that had evidence of recent activation and proliferation. We suggest that UL...
TMPJ-00131	NKG2DL Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	NKG2D ligand 1, also called ULBP1, is a member of UL16-binding protein (ULBP) family which has also been termed the retinoic acid early transcript 1 (RAET1) family. Unlike the classical MHC class I molecules and the MIC ...
TMPK-00134	ULBP-1 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00135	ULBP-1 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Cell surface proteins major histocompatibility complex (MHC) class I-related chain A (MICA) and UL16-binding proteins (ULBP) 1, 2, and 3 are up-regulated upon infection or tumor transformation and can activate human natu...
TMPK-00245	MICB Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antige...
TMPK-00246	MICB Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antige...
TMPK-00247	MICB Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MICB (MHC class I chain-related gene B) is a transmembrane glycoprotein that functions as a ligand for NKG2D. A closely related protein, MICA, shares 85% amino acid identity with MICB.MICB Seems to have no role in antige...
TMPK-00219	MICA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	TMICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly...
TMPY-00575	ULBP-6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in...
TMPY-00190	ULBP-6 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ULBP6/RAET1L, is a polymorphic locus that expresses a functional transcript. ULBP6 had a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands, but expression was detected in...
TMPK-00221	MICA alpha 3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly ...
TMPK-00218	MICA Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly ...
TMPK-00220	MICA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly ...
TMPJ-01212	ULBP-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Mouse ULBP1, also known as RAET1I and NKG2DL1, is a member of the ULBP/RAET1 gene family. ULBP1 plays an important role in immune responses, especially in cancer and infectious diseases, and is well-known to bind to NKG2...
TMPY-03977	DAP10 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	HCST (Hematopoietic Cell Signal Transducer, also known as DAP1) is a Protein Coding gene. HCST belongs to the DAP10 family. It is a transmembrane signaling adaptor that contains a YxxM motif in its cytoplasmic domain. Th...