29
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T35463 | (±)14(15)-EET | (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET | |
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i... | |||
T36070 | (±)5(6)-EET | ||
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5... | |||
T35494 | (±)11(12)-EET | ||
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms C... | |||
T36152 | 14S(15R)-EET | ||
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .114S(15R)-EET binds to isolated guinea pig monocytes with a Kivalue of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2It in... | |||
T35464 | (±)14(15)-EET-SI | ||
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic... | |||
T83451 | 14,15-Epoxyeicosatrienoic acid | 14,15-EET | |
14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease r... | |||
T83868 | (±)13,14-EDT | (±)13,14-Epoxydocosatrienoic Acid,(±)13,14-EpDoTrE,(±)-Dihomo-13,14-EET | |
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat c... | |||
T83869 | (±)16,17-EDT | (±)16,17-Epoxydocosatrienoic Acid,(±)-Dihomo-16,17-EET,(±)16,17-EpDoTrE | |
(±)16,17-EDT, an oxylipin metabolite of adrenic acid produced through the cytochrome P450 (CYP) pathway, effectively induces dilation in isolated porcine arterioles (EC50 = 11 pM) and promotes relaxation of isolated bovi... | |||
T8315 | 1-Cyclohexyl-3-dodecyl urea | CDU,N-Cyclohexyl-N-dodecyl urea,NCND | Epoxide Hydrolase |
1-Cyclohexyl-3-dodecyl urea (NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. | |||
T21609L | Beta-Sheet Breaker Peptide iAβ5 Acetate | Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base) | Others |
Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models. | |||
T38723 | β-Aminoarteether | β-Aminoarteether,SM934 free base | Others |
β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders, including those related to lupus diseases. | |||
T29312 | 1-Piperidineethanol, alpha-(5-(3-hydroxyphenyl)-3-isoxazolyl)- | ||
1-Piperidineethanol, alpha-(5-(3-hydroxyphenyl)-3-isoxazolyl)- is a bioactive chemical. | |||
T125667 | Benzeneethanol, 4-octyl | ||
Benzeneethanol, 4-octyl is a useful organic compound for research related to life sciences. The catalog number is T125667 and the CAS number is 162358-05-6. | |||
T124089 | Preethuliacoumarin | ||
Preethuliacoumarin is a useful organic compound for research related to life sciences. The catalog number is T124089 and the CAS number is 85431-45-4. | |||
T30357 | Benzeneethanol, 3-(1-methylethyl)- | ||
Benzeneethanol, 3-(1-methylethyl)- is a bioactive chemical. | |||
T35731 | Deethylindanomycin | ||
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of... | |||
T124533 | N-Methylcyclohexaneethaneamine | ||
N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences. The catalog number is T124533 and the CAS number is 62141-38-2. | |||
T40833 | ω-Hydroxy-DEET | ||
ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employe... | |||
T65359 | N-FormylglycineEthylEster | ||
N-FormylglycineEthylEster is a useful organic compound for research related to life sciences. The catalog number is T65359 and the CAS number is 3154-51-6. | |||
T125668 | Benzeneethanol, 4-octyl-, 1-acetate | ||
Benzeneethanol, 4-octyl-, 1-acetate is a useful organic compound for research related to life sciences and the catalog number is T125668. | |||
T31361 | Deethyl-LSD | LAE 32,Lysergic acid ethylamide,LAE-32,N-Ethyllysergamide,LAE32 | |
Deethyl-LSD is reported to have some LSD-like effects but is weaker and shorter-lasting, with an active dose reported to be between 0.5 and 1.5 milligrams. | |||
T36151 | 14,15-EE-8(Z)-E | ||
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.... | |||
T36150 | 14,15-EE-5(Z)-E | ||
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity.... | |||
T36556 | (±)5(6)-DiHET lactone | ||
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces... | |||
T37227 | (±)8(9)-DiHET | ||
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy f... | |||
T36462 | CAY10770 | CAY10770 | |
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM).1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167... | |||
T35712 | Debutyldronedarone hydrochloride | SR35021 hydrochloride | |
N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbut... | |||
T37235 | (±)16(17)-EpDPA | (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA | |
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de... | |||
T37333 | (±)11(12)-DiHET MaxSpec® Standard | ||
(±)-11(12)-DiHET is an oxylipin. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formedviaenzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.1,2,3(±)11(... |