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Search Result

Search Results for " eet "

29

Compounds

Cat No. Product Name Synonyms Targets
T35463 (±)14(15)-EET (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
(±)14(15)-EET is a metabolite of arachidonic acid that is formed via epoxidation of arachidonic acid by cytochrome P450.[1],[2] It prevents increases in leukotriene B4, ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) i...
T36070 (±)5(6)-EET
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5...
T35494 (±)11(12)-EET
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher proportion of 11(R),12(S)-EET is produced by the CYP450 isoforms C...
T36152 14S(15R)-EET
14S(15R)-EET is an oxylipin and a cytochrome P450 metabolite of arachidonic acid .114S(15R)-EET binds to isolated guinea pig monocytes with a Kivalue of 612.5 nM in a competitive binding assay using [3H]14(15)-EET.2It in...
T35464 (±)14(15)-EET-SI
Arachidonic acid is metabolized in the vascular endothelium to epoxytrienoic acids (EETs or EpETrEs) by cytochrome P450 enzymes. The EETs are released in response to acetylcholine, bradykinin, arachidonic acid, or cyclic...
T83451 14,15-Epoxyeicosatrienoic acid 14,15-EET
14,15-Epoxyeicosatrienoic acid (14,15-EET), derived from Arachidonic acid metabolism, significantly inhibits platelet aggregation in vivo and enhances astrocytic Aβ clearance, making it relevant for Alzheimer's Disease r...
T83868 (±)13,14-EDT (±)13,14-Epoxydocosatrienoic Acid,(±)13,14-EpDoTrE,(±)-Dihomo-13,14-EET
(±)13,14-EDT, an oxylipin metabolite derived from adrenic acid through the cytochrome P450 (CYP) pathway, acts as a potent activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in isolated rat c...
T83869 (±)16,17-EDT (±)16,17-Epoxydocosatrienoic Acid,(±)-Dihomo-16,17-EET,(±)16,17-EpDoTrE
(±)16,17-EDT, an oxylipin metabolite of adrenic acid produced through the cytochrome P450 (CYP) pathway, effectively induces dilation in isolated porcine arterioles (EC50 = 11 pM) and promotes relaxation of isolated bovi...
T8315 1-Cyclohexyl-3-dodecyl urea CDU,N-Cyclohexyl-N-dodecyl urea,NCND Epoxide Hydrolase
1-Cyclohexyl-3-dodecyl urea (NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor.
T21609L Beta-Sheet Breaker Peptide iAβ5 Acetate Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base) Others
Beta-Sheet Breaker Peptide iAβ5 Acetate (C33H43N5O8) inhibit amyloidogenesis in rat brain models.
T38723 β-Aminoarteether β-Aminoarteether,SM934 free base Others
β-Aminoarteether (SM934 free base), an orally active derivative of Artemisinin, serves a pivotal role in the research of inflammation and autoimmune disorders, including those related to lupus diseases.
T29312 1-Piperidineethanol, alpha-(5-(3-hydroxyphenyl)-3-isoxazolyl)-
1-Piperidineethanol, alpha-(5-(3-hydroxyphenyl)-3-isoxazolyl)- is a bioactive chemical.
T125667 Benzeneethanol, 4-octyl
Benzeneethanol, 4-octyl is a useful organic compound for research related to life sciences. The catalog number is T125667 and the CAS number is 162358-05-6.
T124089 Preethuliacoumarin
Preethuliacoumarin is a useful organic compound for research related to life sciences. The catalog number is T124089 and the CAS number is 85431-45-4.
T30357 Benzeneethanol, 3-(1-methylethyl)-
Benzeneethanol, 3-(1-methylethyl)- is a bioactive chemical.
T35731 Deethylindanomycin
Deethylindanomycin is a polyether antibiotic that has been found in S. setonii. It is active against a variety of Gram-positive bacteria, including various strains of S. aureus and Streptococcus, as well as one strain of...
T124533 N-Methylcyclohexaneethaneamine
N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences. The catalog number is T124533 and the CAS number is 62141-38-2.
T40833 ω-Hydroxy-DEET
ω-Hydroxy-DEET, a significant metabolite of the insect repellent N-N-diethyl-meta-toluamide (DEET), exhibits anti-proliferative properties. DEET, renowned for being a spatial repellent and irritant, is frequently employe...
T65359 N-FormylglycineEthylEster
N-FormylglycineEthylEster is a useful organic compound for research related to life sciences. The catalog number is T65359 and the CAS number is 3154-51-6.
T125668 Benzeneethanol, 4-octyl-, 1-acetate
Benzeneethanol, 4-octyl-, 1-acetate is a useful organic compound for research related to life sciences and the catalog number is T125668.
T31361 Deethyl-LSD LAE 32,Lysergic acid ethylamide,LAE-32,N-Ethyllysergamide,LAE32
Deethyl-LSD is reported to have some LSD-like effects but is weaker and shorter-lasting, with an active dose reported to be between 0.5 and 1.5 milligrams.
T36151 14,15-EE-8(Z)-E
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity....
T36150 14,15-EE-5(Z)-E
Epoxyeicosatrienoic acids (EETs), such as 11(12)-EET and 14(15)-EET, are cytochrome P450 metabolites of arachidonic acid that have been identified as endothelium-derived hyperpolarizing factors with vasodilator activity....
T36556 (±)5(6)-DiHET lactone
5,6-DiHET lactone is a lactonized form of 5,6-EET and 5,6-DiHET. In solution, 5(6)-EET degrades into 5(6)-DiHET and 5(6)-δ-lactone, which can be converted to 5(6)-DiHET and quantified by GC-MS. 5,6-DiHET potently induces...
T37227 (±)8(9)-DiHET
Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. The 8(S),9(R)-EET isomer is metabolized by platelet COX to form 8(S),9(R),11(R)-THETA, a trihydroxy f...
T36462 CAY10770 CAY10770
CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM).1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167...
T35712 Debutyldronedarone hydrochloride SR35021 hydrochloride
N-Desbutyl dronedarone is an active metabolite of the antiarrhythmic agent dronedarone .1,2,3It is formed from dronedarone by cytochrome P450s (CYPs) and monoamine oxidase (MAO) in human hepatocyte preparations.4N-Desbut...
T37235 (±)16(17)-EpDPA (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-de...
T37333 (±)11(12)-DiHET MaxSpec® Standard
(±)-11(12)-DiHET is an oxylipin. 11(S),12(S)-DiHET and 11(R),12(R)-DiHET are vicinal diols formedviaenzymatic hydration of 11(12)-EET by cytosolic or soluble epoxide hydrolases in a non-stereoselective manner.1,2,3(±)11(...

Compounds

(±)14(15)-EET
T35463
Synonym: (±)14,15-EET,(±)14,15-EpETrE,(±)14(15)-EET
Target:
(±)5(6)-EET
T36070
Synonym:
Target:
(±)11(12)-EET
T35494
Synonym:
Target:
14S(15R)-EET
T36152
Synonym:
Target:
(±)14(15)-EET-SI
T35464
Synonym:
Target:
14,15-Epoxyeicosatrienoic acid
T83451
Synonym: 14,15-EET
Target:
(±)13,14-EDT
T83868
Synonym: (±)13,14-Epoxydocosatrienoic Acid,(±)13,14-EpDoTrE,(±)-Dihomo-13,14-EET
Target:
(±)16,17-EDT
T83869
Synonym: (±)16,17-Epoxydocosatrienoic Acid,(±)-Dihomo-16,17-EET,(±)16,17-EpDoTrE
Target:
1-Cyclohexyl-3-dodecyl urea
T8315
Synonym: CDU,N-Cyclohexyl-N-dodecyl urea,NCND
Target: Epoxide Hydrolase
Beta-Sheet Breaker Peptide iAβ5 Acetate
T21609L
Synonym: Beta-Sheet Breaker Peptide iAβ5 Acetate(182912-74-9 Free base)
Target: Others
β-Aminoarteether
T38723
Synonym: β-Aminoarteether,SM934 free base
Target: Others
1-Piperidineethanol, alpha-(5-(3-hydroxyphenyl)-3-isoxazolyl)-
T29312
Synonym:
Target:
Benzeneethanol, 4-octyl
T125667
Synonym:
Target:
Preethuliacoumarin
T124089
Synonym:
Target:
Benzeneethanol, 3-(1-methylethyl)-
T30357
Synonym:
Target:
Deethylindanomycin
T35731
Synonym:
Target:
N-Methylcyclohexaneethaneamine
T124533
Synonym:
Target:
ω-Hydroxy-DEET
T40833
Synonym:
Target:
N-FormylglycineEthylEster
T65359
Synonym:
Target:
Benzeneethanol, 4-octyl-, 1-acetate
T125668
Synonym:
Target:
Deethyl-LSD
T31361
Synonym: LAE 32,Lysergic acid ethylamide,LAE-32,N-Ethyllysergamide,LAE32
Target:
14,15-EE-8(Z)-E
T36151
Synonym:
Target:
14,15-EE-5(Z)-E
T36150
Synonym:
Target:
(±)5(6)-DiHET lactone
T36556
Synonym:
Target:
(±)8(9)-DiHET
T37227
Synonym:
Target:
CAY10770
T36462
Synonym: CAY10770
Target:
Debutyldronedarone hydrochloride
T35712
Synonym: SR35021 hydrochloride
Target:
(±)16(17)-EpDPA
T37235
Synonym: (±)16,17-EpDPE,(±)16,17 EDP,(±)16,17-epoxy Docosapentaenoic Acid,(±)16,17-epoxy DPA,(±)16(17)-EpDPA
Target:
(±)11(12)-DiHET MaxSpec® Standard
T37333
Synonym:
Target:
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