The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.
Cat No. | product name / Synonyms | Species | Expression System |
---|---|---|---|
TMPJ-00388 | FGFR2IIIc Protein, Human, Recombinant (hFc)
FGFR2IIIc Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession ... | |||
TMPJ-00389 | FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 72-95 KDa and the ac... | |||
TMPJ-00390 | FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2IIIb Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession n... | |||
TMPJ-00391 | FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
|
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the... | |||
TMPJ-01224 | FGFRL1 Protein, Human, Recombinant (His)
FGFRL1 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi... | |||
TMPK-00378 | FGFR4 beta Protein, Human, Recombinant (His & Avi)
FGFR4 beta Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the... | |||
TMPK-00379 | FGFR4 Protein, Human, Recombinant (His & Avi)
FGFR4 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the acces... | |||
TMPK-00380 | FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.... | |||
TMPK-00381 | FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa... | |||
TMPK-00384 | FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa ... | |||
TMPK-00385 | FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa a... | |||
TMPK-00386 | FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00387 | FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr... | |||
TMPK-00388 | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa ... | |||
TMPK-00389 | FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa a... | |||
TMPK-00390 | FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh... | |||
TMPK-00391 | FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr... | |||
TMPK-00392 | FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo... | |||
TMPK-00393 | FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa an... | |||
TMPK-00394 | FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo... |