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Fibroblast Growth Factor Receptors, FGFRs

The fibroblast growth factor receptors (FGFR) are receptors that bind to members of the fibroblast growth factor (FGF) family of proteins. The fibroblast growth factor receptors consist of an extracellular ligand domain composed of three immunoglobulin-like domains, a single transmembrane helix domain, and an intracellular domain with tyrosine kinase activity. The FGF/FGFR signalling pathway is involved in a variety of cancers.There are non-selective FGFR inhibitors that act on all of FGFR1-4 and other proteins, and some selective FGFR inhibitors for some/all of FGFR1-4. Selective FGFR inhibitors include AZD4547, BGJ398, JNJ42756493, and PD173074.

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Species
Cynomolgus (3)
Human (50)
Mouse (11)
Rat (2)
Rhesus (6)
Expression System
Baculovirus Insect Cells (3)
HEK293 Cells (68)
Tag
Avi (1)
C-6xHis (1)
C-Avi (2)
C-His (17)
C-His-Avi (20)
C-hFc (14)
GST (3)
His (14)
hFc (6)
Cat No. product name / Synonyms Species Expression System
TMPJ-00388 FGFR2IIIc Protein, Human, Recombinant (hFc)
FGFR2IIIc Protein, Human, Recombinant (hFc)
Human HEK293 Cells
FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession ...
TMPJ-00389 FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
Human HEK293 Cells
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 72-95 KDa and the ac...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2IIIb Protein, Human, Recombinant (hFc)
Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession n...
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
Human HEK293 Cells
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His)
FGFRL1 Protein, Human, Recombinant (His)
Human HEK293 Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi...
TMPK-00378 FGFR4 beta Protein, Human, Recombinant (His & Avi)
FGFR4 beta Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the...
TMPK-00379 FGFR4 Protein, Human, Recombinant (His & Avi)
FGFR4 Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the acces...
TMPK-00380 FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26....
TMPK-00381 FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa...
TMPK-00384 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa ...
TMPK-00385 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa a...
TMPK-00386 FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
TMPK-00387 FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00388 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa ...
TMPK-00389 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa a...
TMPK-00390 FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
TMPK-00391 FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
TMPK-00393 FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
Human HEK293 Cells
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa an...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
FGFR2IIIc Protein, Human, Recombinant (hFc)
TMPJ-00388
FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession ...
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc)
TMPJ-00389
FGFR2 alpha (IIIc) Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 72-95 KDa and the ac...
FGFR2IIIb Protein, Human, Recombinant (hFc)
TMPJ-00390
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession n...
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the...
FGFRL1 Protein, Human, Recombinant (His)
TMPJ-01224
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consi...
FGFR4 beta Protein, Human, Recombinant (His & Avi)
TMPK-00378
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the...
FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the acces...
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00380
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26....
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00381
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa...
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00384
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa ...
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00385
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa a...
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00386
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00387
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00388
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa ...
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00389
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa a...
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00390
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weigh...
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00391
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, thr...
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00393
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa an...
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00394
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabo...
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TargetMol