Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T17257 | WR99210 | 47326-86-3 | 98% |
|
WR99210 is a potent, orally available and less toxic dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 has good antiparasitic activity against P.... | ||||
T76720 | Farletuzumab | 896723-44-7 | SDS-PAGE:95% SEC-HPLC:95% |
Farletuzumab
|
Farletuzumab (MORAb-003) is a potent inhibitor of folate receptor-α (FRα). Farletuzumab is a humanized monoclonal antibody with a high affinity for FRα. Farletuz... | ||||
T76766 | Mirvetuximab | 1453084-36-0 | SDS-PAGE:95% SEC-HPLC:95% |
Mirvetuximab
|
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjuga... | ||||
T0189L | Pemetrexed disodium | 150399-23-8 | 99.92% |
|
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer an... | ||||
T1153 | Trimethoprim | 738-70-5 | 99.81% |
|
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor... | ||||
T8003 | Methotrexate disodium | 7413-34-5 | 99.77% |
|
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor | ||||
T0849 | Pyrimethamine | 58-14-0 | 99.74% |
|
Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug. | ||||
T24403 | Folinic acid | 58-05-9 | 99.7% |
|
Folinic acid (Leucovorin) is a biofolic acid that can be used in the treatment of methotrexate, often in combination with Methotrexate (MTX) to reduce MTX-induce... | ||||
T1485 | Methotrexate | 59-05-2 | 99.46% |
|
Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR. Methotrexate has antimetabolic, antitumor, and immunosuppressive act... | ||||
T0148 | Folinic acid calcium | 1492-18-8 | 99.3% |
|
Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists. | ||||
T2204 | Diaveridine | 5355-16-8 | 99.19% |
|
Diaveridine (AI3-23935) (DVD) is a popular antibacterial synergist that is widely used in combination with sulfonamide. It has been reported to be genotoxic to m... | ||||
T6226 | Pemetrexed disodium hemipenta hydrate | 357166-30-4 | 99.16% |
|
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Diso... | ||||
T8548 | Metoprine | 7761-45-7 | 99.09% |
|
Metoprine is a potent inhibitor of histamine N-methyltransferase (HMT), with potential antineoplastic activity. | ||||
T6120 | Pralatrexate | 146464-95-1 | 98.56% |
|
Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carr... | ||||
T6431 | Levoleucovorin Calcium | 80433-71-2 | 98.46% |
|
Levoleucovorin Calcium (CL307782), a calcium salt of the folinic acid, is used in cancer chemotherapy as an adjuvant. | ||||
T4382 | Proguanil hydrochloride | 637-32-1 | 98.13% |
|
Proguanil hydrochloride (Chloroquanil) is a biguanide compound which metabolizes in the body to form cycloguanil, an anti-malaria agent.Upon hydrolysis, Proguani... | ||||
T7730 | Aminopterin | 54-62-6 | 98% |
|
Aminopterin (4-Aminofolic acid) is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase | ||||
T7593 | Levomefolate calcium | 151533-22-1 | 98% |
|
Levomefolate calcium is an artificial form of folate. It is a coenzymated form of folic acid and a more bioavailable alternative in dietary supplements. | ||||
T16045 | Methotrexate metabolite | 19741-14-1 | 95.28% |
|
Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherape... | ||||
T0148L | Folinic Acid Calcium Salt Pentahydrate | 6035-45-6 | 100% |
|
Folinic Acid Calcium Salt Pentahydrate (Leucovorin Calcium Pentahydrate), a reduced folic acid, is used in combination with other chemotherapeutics. |