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Neurotensin Receptor

The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T23386 SR 142948 184162-64-9
SR 142948
SR 142948 is a neurotensin (NT) receptor antagonist.
T78954 HNTS1R agonist-1 98%
hNTS1R agonist-1
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (B...
T79105 BVFP 357158-20-4 98%
BVFP
BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction betwe...
T79106 SORT-PGRN interaction inhibitor 3 2691846-87-2 98%
SORT-PGRN interaction inhibitor 3
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study o...
TQ0075 ML314 1448895-09-7 98%
ML314
ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
T7617 Neurotensin(8-13) 60482-95-3 98%
Neurotensin(8-13)
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
TP2104L UFP 803 acetate 99.78%
UFP 803 acetate
UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.
T16860 SBI-553 1849603-72-0 99.69%
SBI-553
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
T28217 NTRC-844 1811503-67-9 99.61%
NTRC-844
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
T9044 SORT-PGRN interaction inhibitor 1 100957-85-5 99.56%
SORT-PGRN interaction inhibitor 1
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
TQ0086 AF38469 1531634-31-7 99.56%
AF38469
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
T22476 (±)-AC 7954 hydrochloride 477313-09-0 99.42%
(±)-AC 7954 hydrochloride
(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
T23323 SB 611812 345892-71-9 99.34%
SB 611812
SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.
TP2106L Urantide acetate(669089-53-6 free base) TP2106L 99.22%
Urantide acetate(669089-53-6 free base)
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...
T12848 SB-657510 474960-44-6 98.03%
SB-657510
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...
T7617L Neurotensin(8-13) 3TFA(60482-95-3(free base)) 2952825-79-3 100%
Neurotensin(8-13) 3TFA(60482-95-3(free base))
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
TP1116L Kinetensin acetate(103131-69-7 free base) TP1116L 100%
Kinetensin acetate(103131-69-7 free base)
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
TP1310 Neurotensin 39379-15-2 100%
Neurotensin
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...
T38807L [Lys8, Lys9]-Neurotensin (8-13) acetate 98%
[Lys8, Lys9]-Neurotensin (8-13) acetate
[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...
T77053 Latozinemab 98%
Latozinemab
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interru...
SR 142948
T23386
SR 142948 is a neurotensin (NT) receptor antagonist.
hNTS1R agonist-1
T78954
Compound 10, an hNTS1R agonist-1, acts as a full agonist with a strong affinity for hNTS1R (K i: 6.9 nM), showing the ability to cross the blood-brain barrier (B...
BVFP
T79105
BVFP exhibits affinity for the PGRN 588–593 peptide through binding with a dissociation constant (Kd) of 20 μM and is capable of disrupting the interaction betwe...
SORT-PGRN interaction inhibitor 3
T79106
SORT-PGRN Interaction Inhibitor 3 (Compound 13), with an IC50 value of 0.17 μM, acts as an inhibitor of the SORT-PGRN interaction, and is utilized in the study o...
ML314
TQ0075
ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
Neurotensin(8-13)
T7617
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
UFP 803 acetate
TP2104L
UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.
SBI-553
T16860
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
NTRC-844
T28217
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
SORT-PGRN interaction inhibitor 1
T9044
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
AF38469
TQ0086
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
(±)-AC 7954 hydrochloride
T22476
(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
SB 611812
T23323
SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.
Urantide acetate(669089-53-6 free base)
TP2106L
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...
SB-657510
T12848
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...
Neurotensin(8-13) 3TFA(60482-95-3(free base))
T7617L
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
Kinetensin acetate(103131-69-7 free base)
TP1116L
Kinetensin acetate(103131-69-7 free base) is isolated from pepsin-treated human plasma. Kinetensin acetate(103131-69-7 free base) is a neurotensin-like peptide.
Neurotensin
TP1310
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...
[Lys8, Lys9]-Neurotensin (8-13) acetate
T38807L
[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...
Latozinemab
T77053
Latozinemab (AL001) is a potent and selective recombinant humanized monoclonal antibody against Sortilin.Latozinemab has a high affinity for Sortilin and interru...
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TargetMol