Neurotensin Receptor

The neurotensin receptors are transmembrane receptors that bind the neurotransmitter neurotensin. Two of the receptors encoded by the NTSR1 and NTSR2 genes contain seven transmembrane helices and are G protein coupled. The third receptor has a single transmembrane domain and is encoded by the SORT1 gene.

Cat. No.	Product name	CAS No.	Purity
T28217	NTRC-844	1811503-67-9	98%
NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.
T23386	SR 142948	184162-64-9	98%
SR 142948 is a neurotensin (NT) receptor antagonist.
TQ0075	ML314	1448895-09-7	98%
ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).
T7617	Neurotensin(8-13)	60482-95-3	98%
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
TP2104L	UFP 803 acetate		98%
UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.
T16860	SBI-553	1849603-72-0	98%
SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).
T9044	SORT-PGRN interaction inhibitor 1	100957-85-5	98%
SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).
TQ0086	AF38469	1531634-31-7	98%
AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).
T23323	SB 611812	345892-71-9	98%
SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.
TP2106L	Urantide acetate(669089-53-6 free base)	TP2106L	98%
Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...
T12848	SB-657510	474960-44-6	98%
SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...
T7617L	Neurotensin(8-13) 3TFA(60482-95-3(free base))	2952825-79-3	98%
Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.
TP1116L	Kinetensin acetate(103131-69-7 free base)	TP1116L	98%
Kinetensin acetate is isolated from pepsin-treated human plasma.Kinetensin acetate is a neurotensin-like peptide.
TP1310	Neurotensin	39379-15-2	98%
Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...
T22476	(±)-AC 7954 hydrochloride	477313-09-0	98%
(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.
T38807L	[Lys8, Lys9]-Neurotensin (8-13) acetate		98%
[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...
TP1819L	Substance P 1-9 aceate		98%
Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.

Cat. No.

Product name

CAS No.

Purity

Chemical Structure

T28217

NTRC-844

1811503-67-9

98%

NTRC-844 is a selective rat neurotensin receptor type 2 (NTS2) antagonist that shows analgesic activity in animal models of pain.

T23386

SR 142948

184162-64-9

98%

SR 142948 is a neurotensin (NT) receptor antagonist.

TQ0075

ML314

1448895-09-7

98%

ML314 is an effective molecule agonist of NTR1 (EC50: 1.9 μM).

T7617

Neurotensin(8-13)

60482-95-3

98%

Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

TP2104L

UFP 803 acetate

98%

UFP 803 acetate is a potent ligand of urotensin-II (UT) receptor. UFP-803 displays the activity of a lower residual agonist.

T16860

SBI-553

1849603-72-0

98%

SBI-553 is an effective and brain penetrant NTR1 allosteric modulator (EC50: 0.34 μM).

T9044

SORT-PGRN interaction inhibitor 1

100957-85-5

98%

SORT-PGRN interaction inhibitor 1 is a potent sortilin-progranulin interaction inhibitor(IC50 of 2 μM).

TQ0086

AF38469

1531634-31-7

98%

AF38469 is a new, specific and orally bioavailable Sortilin inhibitor (IC50: 330 nM).

T23323

SB 611812

345892-71-9

98%

SB 611812 is an antagonist of urotensin-II (UT) and can be used in studies about the treatment of cardiovascular disease.

TP2106L

Urantide acetate(669089-53-6 free base)

TP2106L

98%

Urantide acetate is a selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3). Blocks hU-II induced contractions in thoracic aorta ex vivo. E...

T12848

SB-657510

474960-44-6

98%

SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively...

T7617L

Neurotensin(8-13) 3TFA(60482-95-3(free base))

2952825-79-3

98%

Neurotensin(8-13)(3TFA) is Neurotensin (NT) fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

TP1116L

Kinetensin acetate(103131-69-7 free base)

TP1116L

98%

Kinetensin acetate is isolated from pepsin-treated human plasma.Kinetensin acetate is a neurotensin-like peptide.

TP1310

Neurotensin

39379-15-2

98%

Neurotensin is a 13 amino acid neuropeptide that is implicated in the regulation of luteinizing hormone and prolactin release and has significant interaction wit...

T22476

(±)-AC 7954 hydrochloride

477313-09-0

98%

(±)-AC 7954 hydrochloride is a urotensin-II (UT) receptor activator.

T38807L

[Lys8, Lys9]-Neurotensin (8-13) acetate

98%

[Lys8, Lys9]-Neurotensin (8-13) acetate, a Neurotensin analog, exerts its analgesic effects through activation of the G protein-coupled receptors NTS1 and NTS2, ...

TP1819L

Substance P 1-9 aceate

98%

Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.