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MRP

Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer drugs out of the cell.
Cat. No. Product name CAS No. Purity Chemical Structure
T1484 Perindoprilat 95153-31-4 98%
Perindoprilat is an angiotensin-converting enzyme inhibitor.
TN2219 Sophoraisoflavone A 117204-81-6 98%
Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tu...
T9982 PU23 817635-93-1 98%
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
T19866 Indican 487-60-5 98%
Indican is a natural protective compound that is used to protect the liver.
T27954 LY-402913 334970-65-9 98%
LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
T1130 Gramicidin 1405-97-6 98%
A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ...
T1571 Estriol 50-27-1 98%
Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
T8596 Ceefourin 1 315702-40-0 98%
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T0791 Reserpine 50-55-5 98%
Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resul...
T9944 3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide 246238-55-1 98%
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).
T0291 Flurbiprofen 5104-49-4 98%
Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
T0707 Cyclophosphamide hydrate 6055-19-2 98%
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T0450 Fluoxetine 54910-89-3 98%
Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
T0839 Ketoprofen 22071-15-4 98%
Ketoprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inh...
T0866 Propafenone 54063-53-5 98%
Propafenone is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmi...
TN1863 Licoisoflavone A 66056-19-7 98%
Licoisoflavone A is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.
T1484L Perindopril erbumine 107133-36-8 98%
Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihyper...
T0706 Lisinopril dihydrate 83915-83-7 98%
Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1050 Prazosin hydrochloride 19237-84-4 98%
Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not complete...
T1434 Clarithromycin 81103-11-9 98%
Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...
Perindoprilat
T1484
Perindoprilat is an angiotensin-converting enzyme inhibitor.
Sophoraisoflavone A
TN2219
Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tu...
PU23
T9982
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
Indican
T19866
Indican is a natural protective compound that is used to protect the liver.
LY-402913
T27954
LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
Gramicidin
T1130
A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ...
Estriol
T1571
Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
Ceefourin 1
T8596
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
Reserpine
T0791
Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resul...
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
T9944
3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).
Flurbiprofen
T0291
Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
Cyclophosphamide hydrate
T0707
Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
Fluoxetine
T0450
Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
Ketoprofen
T0839
Ketoprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inh...
Propafenone
T0866
Propafenone is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmi...
Licoisoflavone A
TN1863
Licoisoflavone A is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.
Perindopril erbumine
T1484L
Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihyper...
Lisinopril dihydrate
T0706
Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Prazosin hydrochloride
T1050
Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not complete...
Clarithromycin
T1434
Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...
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