MRP

Multidrug resistance proteins (MRPs) are members of the C family of a group of proteins named ATP-binding cassette (ABC) transporters. These ABC transporters together form the largest branch of proteins within the human body. The MRP family comprises of 13 members, of which MRP1 to MRP9 are the major transporters indicated to cause multidrug resistance in tumor cells by extruding anticancer drugs out of the cell.

Cat. No.	Product name	CAS No.	Purity
T1484	Perindoprilat	95153-31-4	98%
T1484	Perindoprilat is an angiotensin-converting enzyme inhibitor.
TN2219	Sophoraisoflavone A	117204-81-6	98%
TN2219	Sophoraisoflavone A is a potential MRP inhibitor; it is also an inhibitor of germ tube growth in the AM fungus Gigaspora margarita, it strongly inhibited germ tu...
T9982	PU23	817635-93-1	98%
T9982	PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
T19866	Indican	487-60-5	98%
T19866	Indican is a natural protective compound that is used to protect the liver.
T27954	LY-402913	334970-65-9	98%
T27954	LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
T1130	Gramicidin	1405-97-6	98%
T1130	A group of peptide antibiotics from BACILLUS brevis. Gramicidin C or S is a cyclic, ten-amino acid polypeptide and gramicidins A, B, D are linear. Gramicidin is ...
T1571	Estriol	50-27-1	98%
T1571	Estriol is a hydroxylated metabolite of ESTRADIOL or ESTRONE that has a hydroxyl group at C3, 16-alpha, and 17-beta position. Estriol is a major urinary estrogen...
T8596	Ceefourin 1	315702-40-0	98%
T8596	Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor.
T0791	Reserpine	50-55-5	98%
T0791	Reserpine is an alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resul...
T9944	3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide	246238-55-1	98%
T9944	3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).
T0291	Flurbiprofen	5104-49-4	98%
T0291	Flurbiprofen is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal dise...
T0707	Cyclophosphamide hydrate	6055-19-2	98%
T0707	Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.
T0450	Fluoxetine	54910-89-3	98%
T0450	Fluoxetine is the first highly specific serotonin uptake inhibitor. It is used as an antidepressant and often has a more acceptable side-effects profile than tra...
T0839	Ketoprofen	22071-15-4	98%
T0839	Ketoprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inh...
T0866	Propafenone	54063-53-5	98%
T0866	Propafenone is only found in individuals that have used or taken this drug. It is an antiarrhythmia agent that is particularly effective in ventricular arrhythmi...
TN1863	Licoisoflavone A	66056-19-7	98%
TN1863	Licoisoflavone A is an MRP inhibitor and inhibits lipid peroxidation with an IC50 of 7.2 μM.
T1484L	Perindopril erbumine	107133-36-8	98%
T1484L	Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihyper...
T0706	Lisinopril dihydrate	83915-83-7	98%
T0706	Lisinopril Dihydrate is an orally bioavailable, long-acting angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T1050	Prazosin hydrochloride	19237-84-4	98%
T1050	Prazosin Hydrochloride reduces peripheral resistance and relaxes vascular smooth muscles as a selective adrenergic alpha-1 antagonist by a mechanism not complete...
T1434	Clarithromycin	81103-11-9	98%
T1434	Clarithromycin is a Macrolide Antimicrobial. The mechanism of action of clarithromycin is as a Cytochrome P450 3A4 Inhibitor, and Cytochrome P450 3A Inhibitor, a...