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Search Result

Search Results for " transplantation "

Targets

c-Met/HGFR

30

Compounds

5

Natural Products

19

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T37596 Terevalefim c-Met/HGFR
Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.
T12783 RWJ 50271 Integrin
RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
T2161 Cardiogenol C Wnt/beta-catenin
Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.
T8005 Cardiogenol C hydrochloride Cardiogenol C HCl,Cardiogenol C Wnt/beta-catenin
Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).
T10009 JAK3-IN-7 JAK
JAK3-IN-7 is a potent and selective JAK3 inhibitor (IC50<0.01 μM) for the treatment of rejection in organ transplantation, graft-versus-host reaction after organ transplantation, autoimmune disorders, allergic diseases, ...
T31795 FK-330 LS-192510,FR-260330,FK330,FK 330 NOS
FK-330 (FR-260330) is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity that prevents ischemia and reperfusion injury in rat liver transplantation.
T6459 Cyclosporine Phosphatase
Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.
T73698 Basiliximab CHI 621 Interleukin
Basiliximab (CHI 621) is a chimeric mouse/human IgG1 monoclonal recombinant antibody against the interleukin-2 receptor. Basiliximab has good immunosuppressive activity and can be used in the study of kidney transplantat...
T68879 FK-330 dihydrate FR-260330 dihydrate NO Synthase
FK-330 dihydrate（FR-260330 dihydrate） is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity to prevent ischemia and reperfusion injury in rat liver transplant...
T76870 Narsoplimab OMS 721 SARS-CoV
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody, a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 and prevents lectin pathway ac...
T76794 Ulocuplumab BMS 936564,MDX 1338 Apoptosis , CXCR
Ulocuplumab (BMS-936564) is a fully human anti-CXCR4 IgG4 antibody.Ulocplumab exhibits antitumor activity in acute myeloid leukemia (AML), non-Hodgkin's lymphoma (NHL), and multiple myeloma transplantation models.Ulocplu...
T15238 Epoprostenol sodium Prostaglandin I2 sodium salt,Prostacyclin sodium salt,Flolan Others
Epoprostenol sodium is a potent inhibitor of platelet aggregation used in pulmonary hypertension and transplantation.
T36944 Ara-G Nucleoside Antimetabolite/Analog
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...
T76951 Zampilimab
Zampilimab (UCB-7858), a monoclonal antibody targeting transglutaminase 2 (TG2), exhibits potential applications in renal transplantation [1] [2].
T19848 Cyclosporin B 7-L-Alanine-cyclosporin A,Antibiotic S 7481F2
Cyclosporin B is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. Cyclosporin B displays antiviral properties, inhibiting the entry of hepatitis B i...
T36910 PF 04449913 maleate
Potent Smo antagonist (IC50 = 5 nM). Attenuates the leukemia-initiation potential of AML cells in a serial transplantation mouse model. Also eliminates self-propagation capacity of AML cells. Munchhof et al (2011) Discov...
T77074 Lulizumab pegol
Lulizumab pegol (BMS-931699) is an antagonist anti-CD28 antibody that effectively inhibits T-cell proliferation, making it a potential therapeutic agent for kidney transplantation and autoimmunity disease research [1].
T64239 Belatacept
Belatacept (BMS 224818) is a selective blocker of T-cell costimulation. Belatacept binds CD 80/86 ligands and thus exhibits an inhibitory effect on CD-28-mediated T-cell costimulation. Belatacept can be used to study org...
T60731 Mitobronitol
Mitobronitol (Myelobromol; DBM) is a brominated analog of mannitol. Mitobronitol is an anticancer agent classified as an alkylating agent. Mitobronitol shows myelosuppression effect that significantly reduced risk for se...
T34833 TH9402 TH 9402,TH-9402,Xanthylium
TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential...
T74568 Phospholipid-PEG-Biotin (MW 20000)
Phospholipid-PEG-Biotin (MW 20000 and MW 3400) is a derivative combining biotin and phospholipid via a linear PEG linker, capable of interacting with avidinylated antibodies. This compound facilitates the modification of...
T81022 Tegoprubart
Tegoprubart is a monoclonal antibody targeting CD40 ligand (CD40L), which plays a critical role in costimulation. By inhibiting CD40L, it diminishes both cellular and antibody-mediated immune responses, fostering a more ...
T74567 Phospholipid-PEG-Biotin (MW 10000)
Phospholipid-PEG-Biotin (MW 10000 and 3400) is a derivative comprising a biotin and a phospholipid connected via a linear PEG linker. This compound is capable of interacting with avidinylated antibodies and is utilized f...
T74566 Phospholipid-PEG-Biotin (MW 5000)
Phospholipid-PEG-Biotin (MW 5000), a derivative of phospholipid PEG, serves to modify the surfaces of liposomes, cells, and pancreatic islets for cell transplantation. This compound incorporates a phospholipid (a lipid f...
T74565 Phospholipid-PEG-Biotin (MW 3400)
Phospholipid-PEG-Biotin (MW 3400) is a derivative of phospholipid PEG, featuring a biotin and a phospholipid connected via a linear PEG linker. This compound has the capability to bind with avidinylated antibodies and is...
T74564 Phospholipid-PEG-Biotin (MW 2000)
Phospholipid-PEG-Biotin (MW 2000), a biotin-labeled phospholipid PEG derivative, is designed for modifying the surfaces of liposomes, cells, and pancreatic islets intended for cell transplantation. This compound integrat...
T74563 Phospholipid-PEG-Biotin (MW 1000)
Phospholipid-PEG-Biotin (MW 1000 and MW 3400) is a derivative of a phospholipid and PEG, featuring a biotin moiety and a phospholipid connected via a linear PEG linker. This compound, particularly with a molecular weight...
T77089 Mirococept
Mirococept (APT070), an antibody designed to target the complement system components C3b/C4b and act as a membrane-localizing C3 convertase inhibitor, effectively diminishes the release of C-peptide and pro-inflammatory ...
T63494 Antitumor agent-60
Antitumor agent-60 is a potent antitumor agent that targets the RAS-RAF signaling pathway and binds to CRAF (Kd: 721.3 nM). antitumor agent-60 increases p53 and ROS levels in cancer cells, resulting in oval and irregular...
T36673 CC 401 dihydrochloride
High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase...

Compounds

Terevalefim
T37596
Synonym:
Target: c-Met/HGFR
RWJ 50271
T12783
Synonym:
Target: Integrin
Cardiogenol C
T2161
Synonym:
Target: Wnt/beta-catenin
Cardiogenol C hydrochloride
T8005
Synonym: Cardiogenol C HCl,Cardiogenol C
Target: Wnt/beta-catenin
JAK3-IN-7
T10009
Synonym:
Target: JAK
FK-330
T31795
Synonym: LS-192510,FR-260330,FK330,FK 330
Target: NOS
Cyclosporine
T6459
Synonym:
Target: Phosphatase
Basiliximab
T73698
Synonym: CHI 621
Target: Interleukin
FK-330 dihydrate
T68879
Synonym: FR-260330 dihydrate
Target: NO Synthase
Narsoplimab
T76870
Synonym: OMS 721
Target: SARS-CoV
Ulocuplumab
T76794
Synonym: BMS 936564,MDX 1338
Target: Apoptosis, CXCR
Epoprostenol sodium
T15238
Synonym: Prostaglandin I2 sodium salt,Prostacyclin sodium salt,Flolan
Target: Others
Ara-G
T36944
Synonym:
Target: Nucleoside Antimetabolite/Analog
Zampilimab
T76951
Synonym:
Target:
Cyclosporin B
T19848
Synonym: 7-L-Alanine-cyclosporin A,Antibiotic S 7481F2
Target:
PF 04449913 maleate
T36910
Synonym:
Target:
Lulizumab pegol
T77074
Synonym:
Target:
Belatacept
T64239
Synonym:
Target:
Mitobronitol
T60731
Synonym:
Target:
TH9402
T34833
Synonym: TH 9402,TH-9402,Xanthylium
Target:
Phospholipid-PEG-Biotin (MW 20000)
T74568
Synonym:
Target:
Tegoprubart
T81022
Synonym:
Target:
Phospholipid-PEG-Biotin (MW 10000)
T74567
Synonym:
Target:
Phospholipid-PEG-Biotin (MW 5000)
T74566
Synonym:
Target:
Phospholipid-PEG-Biotin (MW 3400)
T74565
Synonym:
Target:
Phospholipid-PEG-Biotin (MW 2000)
T74564
Synonym:
Target:
Phospholipid-PEG-Biotin (MW 1000)
T74563
Synonym:
Target:
Mirococept
T77089
Synonym:
Target:
Antitumor agent-60
T63494
Synonym:
Target:
CC 401 dihydrochloride
T36673
Synonym:
Target:
Cat No. Product Name Synonyms Targets
TN4661 Nodosin IL Receptor , Autophagy
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...
T4238 Glycocyamine 2-Guanidinoacetic acid,Guanidoacetic acid Others , Endogenous Metabolite
Glycocyamine (2-Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Glycocyamine is an important marker for renal failure, kidney...
T20578 Maclurin Fustic extract,Morintannic acid,NSC 83240 Free radical scavengers , Reactive Oxygen Species
Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of ...
TJS1779 Protosappanin A PTA NADPH-oxidase , IL Receptor , IκB/IKK , TNF , NF-κB , TLR , ROS , COX , HIV Protease , JAK , NO Synthase , STAT
Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory ...
TL0008 Gigantol Wnt/beta-catenin , Glucosidase
Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...

Natural Products

Nodosin
TN4661
Synonym:
Target: IL Receptor, Autophagy
Glycocyamine
T4238
Synonym: 2-Guanidinoacetic acid,Guanidoacetic acid
Target: Others, Endogenous Metabolite
Maclurin
T20578
Synonym: Fustic extract,Morintannic acid,NSC 83240
Target: Free radical scavengers, Reactive Oxygen Species
Protosappanin A
TJS1779
Synonym: PTA
Target: NADPH-oxidase, IL Receptor, IκB/IKK, TNF, NF-κB, TLR, ROS, COX, HIV Protease, JAK, NO Synthase, STAT
Gigantol
TL0008
Synonym:
Target: Wnt/beta-catenin, Glucosidase

Recombinant Proteins

Species：
Human (12)
Mouse (5)
Rat (1)
Rhesus (1)
Expression System：
HEK293 (15)
E. coli (3)
Baculovirus-Insect Cells (1)
Tag：
Tag Free (5)
hFc (5)
His (4)
C-His (2)
C-His-Avi (1)
C-hFc (1)
His,AVI (1)
Cat No. Product Name Species Expression System
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney...
TMPY-02234 CXCL9 Protein, Human, Recombinant Human E. coli
Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-05636 G-CSF Protein, Mouse, Recombinant Mouse HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829 G-CSF Protein, Human, Recombinant Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPK-00965 MAdCAM-1 Protein, Human, Recombinant (aa 19-317, hFc) Human HEK293
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPK-00966 MAdCAM-1 Protein, Human, Recombinant (aa 19-317, His) Human HEK293
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPK-01031 MAdCAM-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPK-00964 MAdCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) contributes to the recruitment of donor T cells into the mucosal tissues of the recipient after allogeneic hematopoietic stem cell transplantation (aHSCT). The aim of...
TMPY-00708 CD34 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-01652 CD34 Protein, Mouse, Recombinant (His) Mouse HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05582 CD34 Protein, Human, Recombinant (hFc), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-05772 CD34 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06764 CD34 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-00709 CD34 Protein, Human, Recombinant (His) Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-03031 CD34 Protein, Rat, Recombinant (hFc) Rat HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-06716 CD34 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Cluster of Differentiation 34 (CD34) is a member of a family of single-pass transmembrane sialomucin proteins, and may function as a cell-cell adhesion factor. CD34 protein is selectively expressed on hematopoietic proge...
TMPY-02203 CXCL9 Protein, Mouse, Recombinant Mouse E. coli
Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-04255 CXCL9 Protein, Rhesus, Recombinant Rhesus E. coli
Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as Monokine induced by gamma interferon (MIG), is a small cytokine belonging to the CXC chemokine family. The function of this chemokine has not been specifically defi...
TMPY-00813 G-CSF Protein, Human, Recombinant (hFc) Human HEK293
Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
TMPY-02956
Species: Human
Expression System: Baculovirus-Insect Cells
CXCL9 Protein, Human, Recombinant
TMPY-02234
Species: Human
Expression System: E. coli
G-CSF Protein, Mouse, Recombinant
TMPY-05636
Species: Mouse
Expression System: HEK293
G-CSF Protein, Human, Recombinant
TMPY-04829
Species: Human
Expression System: HEK293
MAdCAM-1 Protein, Human, Recombinant (aa 19-317, hFc)
TMPK-00965
Species: Human
Expression System: HEK293
MAdCAM-1 Protein, Human, Recombinant (aa 19-317, His)
TMPK-00966
Species: Human
Expression System: HEK293
MAdCAM-1 Protein, Mouse, Recombinant (His)
TMPK-01031
Species: Mouse
Expression System: HEK293
MAdCAM-1 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00964
Species: Human
Expression System: HEK293
CD34 Protein, Human, Recombinant (hFc)
TMPY-00708
Species: Human
Expression System: HEK293
CD34 Protein, Mouse, Recombinant (His)
TMPY-01652
Species: Mouse
Expression System: HEK293
CD34 Protein, Human, Recombinant (hFc), Biotinylated
TMPY-05582
Species: Human
Expression System: HEK293
CD34 Protein, Human, Recombinant (His), Biotinylated
TMPY-05772
Species: Human
Expression System: HEK293
CD34 Protein, Mouse, Recombinant (hFc)
TMPY-06764
Species: Mouse
Expression System: HEK293
CD34 Protein, Human, Recombinant (His)
TMPY-00709
Species: Human
Expression System: HEK293
CD34 Protein, Rat, Recombinant (hFc)
TMPY-03031
Species: Rat
Expression System: HEK293
CD34 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06716
Species: Human
Expression System: HEK293
CXCL9 Protein, Mouse, Recombinant
TMPY-02203
Species: Mouse
Expression System: E. coli
CXCL9 Protein, Rhesus, Recombinant
TMPY-04255
Species: Rhesus
Expression System: E. coli
G-CSF Protein, Human, Recombinant (hFc)
TMPY-00813
Species: Human
Expression System: HEK293
Cat No. Product Name
L8400 Hematonosis Compound Library

524 compounds
A unique collection of 524 compounds related to hematologic diseases for high throughput screening (HTS) and high content screening (HCS);

Libraries

Hematonosis Compound Library
L8400
Compounds: 524
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