tobacco — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7671	Myosmine		Others , AChR
	Myosmine is a minor tobacco alkaloid that is structurally related to nicotine.		Others , AChR
T20366	Beta-Nicotyrine	Nicotyrine,alpha-Nicotyrine	Others
	beta-Nicotyrine is a tobacco alkaloids Metabolite in the liver.		Others
TN6848	Piperonylic acid	2H-1,3-benzodioxole-5-carboxylic acid	P450
	Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic acid selectively inactivate the CYP73...		P450
TN1130	Yadanziolide A		Antiviral
	Yadanziolide A is a natural product isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor ...		Antiviral
T13857	(R,S)-Anatabine		Others
	(R,S)-Anatabine is a minor tobacco alkaloid found in the Solanaceae family of plants,and can be used as a specific marker for the detection of tobacco use.		Others
T27679	JNJ-39393406		AChR
	JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.		AChR
T3236	Solanesol	Betulanonaprenol,Nonaisoprenol	Others , Endogenous Metabolite , Antibacterial
	Solanesol (Betulanonaprenol) is a phytochemical present in tobacco leaf. Starting material for synthesis of co-enzyme Q10. Exhibits antiulcer activity.		Others , Endogenous Metabolite , Antibacterial
T19122	3-Methylvaleric Acid		Others , Endogenous Metabolite
	3-Methylvaleric Acid is an edible grade flavor present in tobacco.3-Methylvaleric Acid enhances intracellular cAMP accumulation and CRE-luciferase activity in CHO-K1 cells and HEK293 cells.		Others , Endogenous Metabolite
T1202	Cotinine	(-)-Cotinine,S-(-)-Cotinine,(S)-Cotinine,NIH-10498	Endogenous Metabolite , AChR
	Cotinine (NIH-10498) is an alkaloid found in tobacco and is also the predominant metabolite of nicotine.		Endogenous Metabolite , AChR
T7224	Anabasine	(S)-Anabasine,(-)-Anabasine	AChR
	Anabasine ((S)-Anabasine) is an alkaloid extracted from tobacco. Anabasine is a full agonist of nicotinic acetylcholine receptors (nAChRs) with insecticidal activity. Anabasine depolarizes TE671 cells endogenously expres...		AChR
T2904	Sclareolide	Norambreinolide	Others , Antibacterial
	Sclareolide (Norambreinolide) is a sesquiterpene lactone natural product derived from various plant sources including Salvia yosgadensis, Salvia sclarea, and cigar tobacco. It is a close analog of Sclareol, a plant antif...		Others , Antibacterial
T1366	3-Pyridylacetic acid hydrochloride		DPP-4
	3-Pyridylacetic acid hydrochloride (3-PAA-HCl) is a high homologue of niacin. It is a decomposition product of nicotine (and other tobacco alkaloids). It can also react with amines, alcohols and carboxylic acids, and can...		DPP-4
T20533	NNK	Nicotine-derived nitrosamine ketone	Lipoxygenase
	NNK (Nicotine-derived nitrosamine ketone) is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl oxidase which is a tumor suppressor.		Lipoxygenase
T3158	Harmane	Loturine,Harman,Aribine	Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
	Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T67319	2',4'-Dimethylacetophenone		Endogenous Metabolite
	2',4'-Dimethylacetophenone is a chemical that can be used in biological research. The compound can be used in gas chromatography to detect aldosterone aroma in tobacco compounds and can be used to protect food products.		Endogenous Metabolite
T35455	N-Nitrosodiethylamine	Diethylnitrosamine,NDEA	DNA/RNA Synthesis
	N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in water, tobacco smoke, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitroso...		DNA/RNA Synthesis
T36696	DMBA
	7,12-Dimethylbenz[a]anthracene (DMBA) is a polycyclic aromatic hydrocarbon (PAH) that has been found in tobacco smoke and diesel exhaust and has carcinogenic activity.1,2It undergoes metabolic activation by numerous enzy...
TN4655	Nicotine 1'-N-oxide		Others
	Nicotine 1'-N-oxide is a natural product from tobacco smoke.		Others
TN1436	Methyl 4-Hydroxyphenylacetate		Antifection
	Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).		Antifection
T20781	Maleic hydrazide	Antergon,Antyrost,Hydrazide maleique,Burtolin
	Maleic hydrazide, a herbicide, inhibits the sprouting in vegetables and stored root crops, prevents sucker production in tobacco plants, controls the growth of foliage, and grass.