mannose

DSPE-PEG(2000)-mannose, a pegylated and mannosylated derivative of 1,2-DSPE, has been employed in both in vitro and in vivo studies for delivering peptides, oligodeoxynucleotides, and siRNA via liposomes and lipid nanoparticles (LNPs). Fluorescently labeled LNPs containing DSPE-PEG(2000)-mannose predominantly accumulate in the liver and spleen of mice, significantly more so than in the brain, lungs, heart, kidneys, and pancreas. In immunization studies, liposomes encapsulating Human Papillomavirus type 16 (HPV16) E7 peptides with CpG oligodeoxynucleotides as an adjuvant led to reduced tumor volume and decreased numbers of CD4+ or CD8+ T cells and angiogenesis within tumors in a mouse lung cancer model using TC-1 cells.

Mannose triflate is a glucose analog utilized as a precursor in the synthesis of 18F-FDG for PET applications. It binds with 18F through an SN2 nucleophilic substitution reaction. Mannose triflate is applicable in imaging techniques for cancer detection.

α-D-Mannose pentaacetate is a biochemical reagent that serves as a biomaterial or organic compound in life science research.

2,3,4,6-Tetra-O-benzoyl-D-mannopyranose is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Concanavalin A is a natural product, a phytoalexin (glycan-binding protein). Concanavalin A has antitumor activity and can also induce acute liver injury.

M6 glycan (Man6), 2-AA labelled (Mannose-6 N-linked oligosaccharide, 2-AA labelled; Oligomannose 6 glycan, 2-AA labelled) is a polymeric N-glycoprotein acting as a versatile fluorescent linker. The resulting conjugate exhibits high sensitivity and specificity by mimicking the antennae components of N-glycans.

M6 glycan (Man6) (Mannose-6 N-linked oligosaccharide; Oligomannose 6 glycan) is a polymeric N-linked glycoprotein that serves as a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M5 glycan (Man5), 2-AA labelled (Mannose-5 N-linked oligosaccharide, 2-AA labelled; Oligomannose 5 glycan, 2-AA labelled) is a type of N-linked glycoprotein that acts as a versatile fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antenna structures of N-glycans.

M8 glycan (Man8) (Mannose-8 N-linked oligosaccharide; Oligomannose 8 glycan) is a polymeric N-glycoprotein and serves as a versatile fluorescent linker. The resulting conjugate, by mimicking the antenna components of N-glycans, exhibits high sensitivity and specificity.

M9 glycan (Man9), 2-AA labelled (Mannose-9 N-linked oligosaccharide, 2-AA labelled; Oligomannose 9 glycan, 2-AA labelled) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugate exhibits high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M9 glycan (Man9) (Mannose-9 N-linked oligosaccharide; Oligomannose 9 glycan) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M8 glycan (Man8), 2-AB labelled (Mannose-8 N-linked oligosaccharide, 2-AB labelled; Oligomannose 8 glycan, 2-AB labelled) is a polymeric N-glycoprotein and serves as a versatile fluorescent linker. The resulting conjugate exhibits high sensitivity and specificity by mimicking the arm components of N-glycans.

M7 glycan (Man7), 2-AB labelled (Mannose-7 N-linked oligosaccharide, 2-AB labelled; Oligomannose 7 glycan, 2-AB labelled) is a polymeric N-linked glycoprotein that serves as a versatile fluorescent linker. The resulting conjugate, by mimicking the antennae elements of N-glycans, exhibits high sensitivity and specificity.

M5 glycan (Man5), 2-AB labelled (Mannose-5 N-linked oligosaccharide, 2-AB labelled; Oligomannose 5 glycan, 2-AB labelled) is a type of polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugate mimics the antenna components of N-glycans, offering high sensitivity and specificity.

M7 glycan (Man7), procainamide labelled (Mannose-7 N-linked oligosaccharide, procainamide labelled; Oligomannose 7 glycan, procainamide labelled) is a polymeric N-glycoprotein functioning as a versatile fluorescent linker. The conjugate obtained simulates the antenna elements of N-glycans, providing high sensitivity and specificity.

M8 glycan (Man8), 2-AA labelled (Mannose-8 N-linked oligosaccharide, 2-AA labelled; Oligomannose 8 glycan, 2-AA labelled) is a polymeric N-glycoprotein and serves as a versatile fluorescent linker. The resulting conjugates, achieved through the mimicry of N-glycan antennae components, exhibit high sensitivity and specificity.

M7 glycan (Man7) (Mannose-7 N-linked oligosaccharide; Oligomannose 7 glycan) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M5 glycan (Man5), APTS labelled (Mannose-5 N-linked oligosaccharide, APTS labelled; Oligomannose 5 glycan, APTS labelled), is a multifunctional fluorescent linker, characterized as a polymeric N-glycoprotein. The resulting conjugate exhibits high sensitivity and specificity by mimicking the antenna structure of N-glycans.

M7 glycan (Man7), 2-AA labelled (Mannose-7 N-linked oligosaccharide, 2-AA labelled; Oligomannose 7 glycan, 2-AA labelled) is a polymeric N-glycoprotein functioning as a versatile fluorescent linker. The resulting conjugates offer high sensitivity and specificity by mimicking the antennal elements of N-glycans.

M3 glycan (Man3) (Mannose-3 N-linked oligosaccharide; Oligomannose 3 glycan) is a multifunctional fluorescent linker composed of poly N-glycoprotein. The resulting conjugates feature high sensitivity and specificity by mimicking the antenna elements of N-glycans.

M8 glycan (Man8), procainamide labelled (Mannose-8 N-linked oligosaccharide, procainamide labelled; Oligomannose 8 glycan, procainamide labelled), is a multifunctional fluorescent linker used in poly-N-glycoproteins. The conjugates formed display high sensitivity and specificity by mimicking the antennal elements of N-glycans.

M6 glycan (Man6), procainamide labelled (Mannose-6 N-linked oligosaccharide, procainamide labelled), is a multifunctional fluorescent linker that serves as a polymer of N-glycoprotein. The resulting conjugate mimics the antennal elements of N-glycans, offering high sensitivity and specificity.

M9 glycan (Man9), 2-AB labelled (Mannose-9 N-linked oligosaccharide, 2-AB labelled; Oligomannose 9 glycan, 2-AB labelled), is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates mimic the antenna elements of N-glycans, offering high sensitivity and specificity.

M5 glycan (Man5) (Mannose-5 N-linked oligosaccharide; Oligomannose 5 glycan) is a polymeric N-glycoprotein that serves as a versatile fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennae elements of N-glycans.