dpd

DPD 20027 is a bioactive chemical.

2,4-DPD is competitive inhibitor of the oxygen-sensing enzyme HIF-α prolyl hydroxylase (HIF-PH)

5,6-Dihydrouracil (5,6-Dihydrouracil) is an intermediate breakdown product of uracil.

TAS-114 is an orally active dual inhibitor of dUTPase and dihydropyrimidine dehydrogenase (DPD). TAS-114 targets the intercellular metabolism of 5-FU to enhance antitumor activity and modulates catabolic pathways to improve the systemic availability of 5-FU.

Eniluracil (GW776C85) is an orally activedihydropyrimidine dehydrogenase (DPD) inhibitor,increases the oral bioavailability of 5-FU to 100%, facilitating uniform absorption and predictable toxicity.

dPDL1-4 is a potent and selective eHSPTAC eHSP90PD-L1 degrader, with DC50 values of 7.77 μM (HeLa) and 6.52 μM (B16F10). It links eHSP90 to target proteins, inducing lysosomal degradation. dPDL1-4 effectively degrades PD-L1 and inhibits tumor growth, making it useful for research in cervical cancer and melanoma.

MDPD is an enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis. MDPD alleviates the growth inhibitory effects of NAE 12:0, in part by enhancing the enzymatic activity of Arabidopsis FAAH (AtFAAH).

DPDPE is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.

DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo.

2-Phenylpyrrolidine ,with CAS No. 1006-64-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Phenylpyrrolidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

3-Phenylpyridine ,with CAS No. 1008-88-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 3-Phenylpyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Diphenylmethane ,with CAS No. 101-81-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Diphenylmethane provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

N'-benzyl-N,N-dimethylethylenediamine ,with CAS No. 103-55-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. N'-benzyl-N,N-dimethylethylenediamine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(R)-2,3-dihydro-1H-inden-1-amine hydrochloride ,with CAS No. 10305-73-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. (R)-2,3-dihydro-1H-inden-1-amine hydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Methyl 2-cyclohexyl-2-hydroxyphenylacetate ,with CAS No. 10399-13-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Methyl 2-cyclohexyl-2-hydroxyphenylacetate provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5,6,7,8-Tetrahydroquinoline ,with CAS No. 10500-57-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5,6,7,8-Tetrahydroquinoline provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Glycine anhydride ,with CAS No. 106-57-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Glycine anhydride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Benzylhydrazine monohydrochloride ,with CAS No. 1073-62-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Benzylhydrazine monohydrochloride provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Isocytosine ,with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Isocytosine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

4,6-Dimethyl-2-hydroxypyrimidine ,with CAS No. 108-79-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4,6-Dimethyl-2-hydroxypyrimidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Dihydrochalcone ,with CAS No. 1083-30-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Dihydrochalcone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Morpholin-3-one ,with CAS No. 109-11-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Morpholin-3-one provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

2-Aminopyrimidine ,with CAS No. 109-12-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2-Aminopyrimidine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Glutarimide ,with CAS No. 1121-89-7, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Glutarimide provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.