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Search Result

Search Results for "depressive disorder"

Compounds

Cat No. Product Name
T7061 Duloxetine Serotonin Transporter
Duloxetine 是一种 5 羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂，Ki=4.6 nM，可作用于广泛性焦虑症的研究。
T22453 Venlafaxine 文拉法辛,Wy 45030 Serotonin Transporter
Venlafaxine 是一种口服有效的 5-羟色胺 (5-HT)/去甲肾上腺素 (NE) 重摄取的双重抑制剂，具有抗抑郁活性。
T1279 Vilazodone SB659746A,EMD 68843,维拉佐酮 5-HT Receptor , Serotonin Transporter
Vilazodone 是一种可口服的选择性 5 -羟色胺再摄取抑制剂 (SSRI) 和部分5-HT1A 受体激动剂。它有抗抑郁作用，可用于抑郁症和情绪性疾病的研究。
T68172 Zalospirone 5-HT Receptor
Zalospirone 是一种5-HT1A 受体激动剂，可用于研究焦虑症和重度抑郁症。
T15799 LY2940094 LY-2940094 Opioid Receptor
LY2940094 是一种口服有效的选择性 NOP 受体拮抗剂，可降低动物模型的自身给药酒精依赖，对 NOP 受体具有高亲和力，Ki 为 0.105 nM，和拮抗活力，Kb 为 0.166 nM。
T21013 Clomipramine Anafranil (free base),Clomicalm,Clomipramina,Chlorimipramine,Anafranil,氯米帕明 5-HT Receptor
Clomipramine 是一种三环类抗抑郁药，能够有效阻断 5-HT 再摄取 (IC50:1.5 nM) ，可用于研究强迫症 (OCD) 及抑郁症。
T22442 Trazodone AF-1161,曲唑酮 5-HT Receptor
Trazodone 是一种 5-HT 2A/2C 受体拮抗剂，用作治疗主要焦虑症和抑郁症的抗抑郁药。
T6232 Vilazodone Hydrochloride 盐酸维拉佐酮,SB659746A,Vilazodone HCl,EMD 68843 Others , Serotonin Transporter , 5-HT Receptor
Vilazodone Hydrochloride 是 5-HT1A 受体和特异性 5-羟色胺再摄取抑制剂 (SSRI) 的部分激动剂，用于治疗重度抑郁症。
T7805 GW791343 dihydrochloride GW791343 (HCl) P2X Receptor
GW791343 dihydrochloride 是有种属特异性的 P2X7变构调节剂，对人 P2X7的 pIC50为6.9-7.2。
T14782 Brilaroxazine RP5063 5-HT Receptor , Dopamine Receptor
Brilaroxazine 是一种有效的多模式多巴胺/5-HT 调节剂。 Brilaroxazine 是多巴胺 D2、D3 和 D4 受体、5-HT1A (Ki = 1.5 nM) 和 5-HT2A (Ki = 2.5 nM) 的部分激动剂...
T64317 ZZL-7 Serotonin Transporter
ZZL-7是一种起效快的抗抑郁药。ZZL-7破坏中缝背核（DRN）神经元一氧化氮合酶（nNOS）和血清素转运蛋白（SERT）之间的相互作用。ZZL-7可以很容易地穿过血脑屏障。ZZL-7在重度抑郁症（MDD）中具有研究价值。
T1445 Agomelatine Valdoxan,Thymanax,阿戈美拉汀,S-20098 Melatonin Receptor , 5-HT Receptor
Agomelatine 是褪黑激素受体的强效激动剂和 5-羟色胺-2C (5-HT2C) 受体的拮抗剂，在猪和人 5-HT2C 克隆受体中pKi 分别为 6.4 和 6.2。
T3933 Jatrorrhizine 药根碱,neprotin,Yatrorizine AChE , Antibacterial , MAO , 5-HT Receptor
Jatrorrhizine 是一种从黄连中分离得到的生物碱，具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
T1471 Duloxetine hydrochloride 盐酸度洛西汀,Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl Serotonin Transporter , Dopamine Receptor , 5-HT Receptor , Norepinephrine
Duloxetine hydrochloride 是一种 5-羟色胺-去甲肾上腺素重吸收 (serotonin-norepinephrine reuptake) 抑制剂 (SNRI)，Ki=4.6 nM，可用于广泛性焦虑症的研究。
T4912 Jatrorrhizine chloride Yatrorhizine chloride,Neprotine chloride,盐酸药根碱 Others , 5-HT Receptor , OCT , Antibacterial , AChE
Jatrorrhizine chloride 是从黄连中分离得到的生物碱，具有神经保护、抗菌、抗氧化和抗疟原虫活性。它通过抑制摄取2转运蛋白的活性减少血清素和去甲肾上腺素的摄取。它是具有口服活性的乙酰胆碱酯酶抑制剂。
T69364 Elzasonan
Elzasonan is a selective 5-hydroxytryptamine 1B receptor antagonist used to treat patients with major depressive disorde...
T71389 Fluoxetine oxalate
Fluoxetine oxalate is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used for the t...
T71587 Fluoxetine succinate ester
Fluoxetine succinate ester is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It is used f...
T27599 Imiloxan RS 21361,RS-21361,RS21361
Imiloxan, an α2 adrenergic receptor antagonist, is used potentially for the treatment of major depressive disorder.
T61544 Edivoxetine hydrochloride
Edivoxetine hydrochloride is a highly effective and specialized compound used primarily as a norepinephrine reuptake inh...
Duloxetine
T7061
synonym:
Target:
Venlafaxine
T22453
synonym: 文拉法辛,Wy 45030
Target:
Vilazodone
T1279
synonym: SB659746A,EMD 68843,维拉佐酮
Target:
Zalospirone
T68172
synonym:
Target:
LY2940094
T15799
synonym: LY-2940094
Target:
Clomipramine
T21013
synonym: Anafranil (free base),Clomicalm,Clomipramina,Chlorimipramine,Anafranil,氯米帕明
Target:
Trazodone
T22442
synonym: AF-1161,曲唑酮
Target:
Vilazodone Hydrochloride
T6232
synonym: 盐酸维拉佐酮,SB659746A,Vilazodone HCl,EMD 68843
Target:
GW791343 dihydrochloride
T7805
synonym: GW791343 (HCl)
Target:
Brilaroxazine
T14782
synonym: RP5063
Target:
ZZL-7
T64317
synonym:
Target:
Agomelatine
T1445
synonym: Valdoxan,Thymanax,阿戈美拉汀,S-20098
Target:
Jatrorrhizine
T3933
synonym: 药根碱,neprotin,Yatrorizine
Target:
Duloxetine hydrochloride
T1471
synonym: 盐酸度洛西汀,Duloxetine HCl,LY-248686 hydrochloride,(S)-Duloxetine hydrochloride,LY-248686 HCl
Target:
Jatrorrhizine chloride
T4912
synonym: Yatrorhizine chloride,Neprotine chloride,盐酸药根碱
Target:
Elzasonan
T69364
synonym:
Target:
Fluoxetine oxalate
T71389
synonym:
Target:
Fluoxetine succinate ester
T71587
synonym:
Target:
Imiloxan
T27599
synonym: RS 21361,RS-21361,RS21361
Target:
Edivoxetine hydrochloride
T61544
synonym:
Target:
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