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Results for "

depressive disorder

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    35
    TargetMol | Inhibitors_Agonists
  • Natural Products
    2
    TargetMol | Natural_Products
  • Isotope Products
    2
    TargetMol | Isotope_Products
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    1
    TargetMol | Inhibitors_Agonists
gw791343 dihydrochloride
GW791343 (HCl)
T78051019779-04-4
GW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.
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TargetMol | Inhibitor Sale
Imiloxan
RS-21361, RS21361, RS 21361
T2759981167-16-0In house
Imiloxan (RS-21361) is an α2 adrenergic receptor antagonist used in the treatment of major depressive disorder.
  • Inquiry Price
6-8 weeks
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Liafensine
BMS820836, BMS 820836, DB104, BMS-820836
T327371198790-53-2In house
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders.
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6-8weeks
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Zalospirone
T68172114298-18-9In house
Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder.
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Vilazodone
SB659746A, EMD 68843
T1279163521-12-8
Vilazodone (SB659746A) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) and a 5-HT-1A receptor partial agonist, with antidepressant and anti-anxiety activities. Vilazodone inhibits the reuptake of serotonin from the synaptic cleft while stimulating the release of 5-HT into the synaptic cleft. This increases the concentration of 5-HT in the synaptic cleft and potentiates serotonergic neurotransmission in the central nervous system.
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Agomelatine
Valdoxan, Thymanax, S-20098
T1445138112-76-2
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
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Venlafaxine
Wy 45030
T2245393413-69-5
Venlafaxine (Wy 45030), an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), is used to treat major generalised anxiety disorder (GAD), depressive disorder (MDD), panic disorder and social phobia.
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Vilazodone Hydrochloride
SB659746A, EMD 68843, Vilazodone HCl
T6232163521-08-2
Vilazodone Hydrochloride (EMD 68843) , a partial agonist of 5-HT1A receptors and specific serotonin reuptake inhibitor (SSRI), is utilized in treating of the major depressive disorder.
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LY2940094
LY-2940094
T157991307245-86-8
LY2940094 (LY-2940094) decreases ethanol self-administration in animal models. LY2940094 is an effective, selective, and orally available nociceptin receptor antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM).
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Jatrorrhizine
Yatrorizine, neprotin
T39333621-38-3
Jatrorrhizine (neprotin) is a protoberberine alkaloid isolated from Enantia chlorantha (Annonaceae) and other species. It was found to have antimicrobial and antifungal activity. It binds and noncompetitively inhibits monoamine oxidase (IC50 4 micromolar for MAO-A and 62 for MAO-B).
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ZZL-7
T6431799141-91-0
ZZL-7 is a fast-onset antidepressant agent that disrupts the interaction between neuronal nitric oxide synthase (nNOS) and the serotonin transporter (SERT) in the dorsal raphe nucleus (DRN). It easily crosses the blood-brain barrier and has research value in major depressive disorder (MDD).
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TargetMol | Inhibitor Sale
Duloxetine D3 hydrochloride
(S)-Duloxetine D3 hydrochloride,LY248686 D3 hydrochloride
T111131435727-97-1
Duloxetine D3 hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for the treatment of major depressive disorder and generalized anxiety disorder (GAD). Duloxetine D3 hydrochloride ((S)-Duloxetine D3 hydrochloride) is a deuterium-labeled Duloxetine hydrochloride.
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Duloxetine hydrochloride
Duloxetine HCl, LY-248686 hydrochloride, (S)-Duloxetine hydrochloride, LY-248686 HCl
T1471136434-34-9
Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a thiophene derivative and selective neurotransmitter uptake inhibitor for serotonin and noradrenaline (SNRI). It is an antidepressant agent and anxiolytic, also used for treating pain in patients with diabetes mellitus and fibromyalgia.
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Brilaroxazine
RP5063
T147821239729-06-6
Brilaroxazine (RP5063) is a potent multimodal dopamine 5-HT modulator. Brilaroxazine is a partial agonist of dopamine D2, D3, and D4 receptors, 5-HT1A (Ki =1.5 nM) and 5-HT2A (Ki = 2.5 nM), and has antagonist activity 5-HT2B, and 5-HT7 receptors with Kis of 0.19 nM and 2.7 nM, respectively. Brilaroxazine can be used for research about cognitive impairments in neuropsychiatric and neurological diseases.
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6-8 weeks
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Orvepitant maleate
GW823296 maleate
T16406579475-24-4
Orvepitant maleate is an effective, selective, and well-tolerated neurokinin-1 receptor (NK-1) antagonist (pKi: 10.2 for human neurokinin-1 receptor). Orvepitant maleate has the potential for depressive disorder and chronic refractory cough (CRC) treatmen
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8-10 weeks
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Gepirone hydrochloride
T20420883928-66-9
Gepirone is a selective 5-HT1A agonist that selectively binds to 5-HT1A receptor sites. It is employed as an antidepressant in research studies focused on anxiety and major depressive disorder.
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10-14 weeks
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Clomipramine
Clomicalm, Anafranil, Clomipramina, Anafranil (free base), Chlorimipramine
T21013303-49-1
Clomipramine (Clomicalm) is a tricyclic antidepressant (TCA). It is used for the treatment of the panic disorder, obsessive-compulsive disorder, major depressive disorder, and chronic pain. It may decrease the risk of suicide in those over the age of 65. It is similar to Imipramine in that selective inhibition of the serotonin uptake in the brain.
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Trazodone
AF-1161
T2244219794-93-5
Trazodone (AF-1161), a 5-HT 2A 2C receptor antagonist, is used as an antidepressant for treating major anxiety disorders and depressive disorder.
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Flerobuterol HCl
CRL-40996,CRL40996,CRL 40996,Flerobuterol hydrochloride
T2733182101-08-4
Flerobuterol is a β adrenergic receptor agonist potentially for the treatment of major depressive disorder. Flerobuterol enhances serotonergic neurotransmission. Flerobuterol acutely increases 5-HT synthesis, in part, through an elevation of brain Trp ava
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6-8 weeks
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LY2940094 tartrate
LY2940094,LY 2940094,LY-2940094 tartrate,LY-2940094
T279391307245-87-9
LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism.
  • Inquiry Price
1-2 weeks
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Jatrorrhizine chloride
Yatrorhizine chloride, Neprotine chloride
T49126681-15-8
Jatrorrhizine chloride (Neprotine chloride) is a potent and orally active uptake-2 transporter inhibitor. It exhibits a critical neuroprotective role in H2O2-induced apoptosis via inhibition of the MAPK pathway in HT22 hippocampal neurons.
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7-10 days
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(±)-Duloxetine hydrochloride
T61008947316-47-4
(±)-Duloxetine ((Rac)-Duloxetine) hydrochloride is the racemate of Duloxetine hydrochloride and is used in research for diabetic neuropathic pain, fibromyalgia, and major depressive disorder as a serotonin-norepinephrine reuptake inhibitor [1].
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6-8 weeks
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Edivoxetine hydrochloride
T615441194374-05-4
Edivoxetine hydrochloride is a highly effective and specialized compound used primarily as a norepinephrine reuptake inhibitor (NERI), indicated for the treatment of depressive disorder and attention-deficit hyperactivity disorder.
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6-8 weeks
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GW791343 trihydrochloride
GW791343 3HCl
T6526309712-55-8
GW791343 trihydrochloride (GW791343 3HCl) is aHCl salt form of GW791343, which is a non-competitive allosteric modulator of human P2X7 receptor inhibitor with pIC50 of 7.
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1-2 weeks
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