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Search Result

Search Results for "cardiac function"

Libraries

Potassium Channel Blocker Library Drug-induced Liver Injury (DILI) Compound Library
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Compounds

Cat No. Product Name
T15050 Danicamtiv SAR 440181,MYK-491 Myosin
Danicamtiv 是一种正性肌力药物，也是一种心肌肌球蛋白的选择性变构激活剂，可增加心脏收缩功能并保持机械效率。
T15052 Dapansutrile NOD-like Receptor (NLR) , NOD
Dapansutrile 是一种口服有活性的 NLRP3 炎性小体选择性抑制剂。它具有抗炎特性，可用于研究缓解疼痛。
TP2058L Catestatin acetate AChR , Endogenous Metabolite
Catestatin acetate 是 nAChR 的非竞争性拮抗剂，可抑制儿茶酚胺的释放。 Catestatin acetate 调节心脏功能和血压。
T28881 Sulmazole AR-L 115BS,AR-L 115-BS,Vardax
Sulmazole is a positive inotrope sulmazole. Sulmazole inhibits the function of guanine nucleotide regulatory proteins by...
TCO2745 Cyclic AMP 腺苷环磷酸酯,环磷腺苷,Adenosine Cyclophosphate,Adenosine 3',5'-cyclophosphate,cAMP,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP Others , Endogenous Metabolite
Cyclic AMP (cAMP) 是有丝分裂信使，可以促进 G1期到 S 期的细胞周期进程。
T9232 Mitochondrial fusion promoter M1 Mitochondrial Metabolism
Mitochondrial fusion promoter M1 是一种线粒体动态调节剂，能够保持线粒体功能并促进细胞呼吸，减轻心肌缺血/再灌注大鼠的心脏损伤和大脑损伤。
T2750 Ginkgolide C BN-52022,银杏内酯C Endogenous Metabolite , AMPK , MMP , Sirtuin
Ginkgolide C 是从银杏叶中分离到的一种黄酮类天然产物，可增强体内大鼠的心脏功能，具有减少血小板聚集，改善阿尔兹海默症等作用。
T68037L CBS-1114 HCl N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base) Lipoxygenase
CBS-1114 HCl 是一种5-脂氧合酶抑制剂，是一种良好眼睛渗透型号的抗炎化合物。CBS-1114 HCl 可以保持和改善心脏功能，减轻心功能障碍，以及减少患有心血管疾病的受试者的心外膜脂肪组织和/或心包脂肪组织。
T14875 Indocyanine green 吲哚菁绿,Foxgreen,IC Green,Cardiogreen Others
Cardiogreen 是低毒性荧光剂，普遍用于医学诊断，包括确定心输出量，肝功能和肝血流量，以及用于眼科血管造影。
TP1937L1 RFRP-1 (human) acetate(311309-25-8 free base) Neuropeptide Y Receptor
RFRP-1 (human) acetate(311309-25-8 free base) 是一种有效的内源性 NPFF 受体激动剂（NPFF2 和 NPFF1 的 EC50 值分别为 0.0011 和 29 nM）。它减弱离体大鼠和兔心肌...
T36569 KR-32568 Sodium Channel
KR-32568是一种钠/氢交换器1（NHE-1）抑制剂（IC50：230 nM）。KR-32568具有强大的心脏保护作用。当使用浓度为10μM 时，它能在离体的缺血大鼠心脏模型中恢复心脏收缩功能。KR-32568（0.3mg/kg）在缺血...
T3893 Forsythoside B 连翘酯苷 B,连翘脂苷B TNF , NF-κB
Forsythoside B 是传统中药植物独一味叶子中分离的一种苯乙醇苷。它可抑制 TNF-alpha，IL-6，IκB， 调节 NF-κB。它抑制炎症反应，具有抗氧化和神经保护作用。
T33451 ML 7 ML7,ML-7
ML 7 is an inhibitor of myosin light chain kinase that protects cardiac function from ischemia/reperfusion (I/R) injury.
T70699 SAR296968
SAR296968 is a novel selective NCX inhibitor, improving cardiac function and restoring sympathovagal balance in heart fa...
T75947 RFRP-1(human) TFA
RFRP-1(human) TFA is a potent endogenous NPFF receptor agonist (EC50values are 0.0011 and 29 nM for NPFF2 and NPFF1, res...
T31640 Enrasentan SB 217242,SB-217242,SB217242
Enrasentan (sb-217242) is a dual receptor corticosteroid antagonist with a higher affinity for ET (a) receptor, which ca...
T16332 NKH477 Colforsin dapropate hydrochloride NMDAR
NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects...
TP1937 RFRP-1(human) RFRP-1 (human)
Potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates...
T70280 KB-R7785
KB-R7785 is a novel ADAM12 and MMP inhibitor, ameliorating cardiac function in a transverse aortic constriction (TAC) mo...
T35839 3-Iodothyronamine (hydrochloride)
3-Iodothyronamine is derived from the deiodination and decarboxylation of endogenous thyroxine. It activates the G prote...
Danicamtiv
T15050
synonym: SAR 440181,MYK-491
Target:
Dapansutrile
T15052
synonym:
Target:
Catestatin acetate
TP2058L
synonym:
Target:
Sulmazole
T28881
synonym: AR-L 115BS,AR-L 115-BS,Vardax
Target:
Cyclic AMP
TCO2745
synonym: 腺苷环磷酸酯,环磷腺苷,Adenosine Cyclophosphate,Adenosine 3',5'-cyclophosphate,cAMP,Cyclic 3',5'-monophosphate adenosine,3',5'-AMP
Target:
Mitochondrial fusion promoter M1
T9232
synonym:
Target:
Ginkgolide C
T2750
synonym: BN-52022,银杏内酯C
Target:
CBS-1114 HCl
T68037L
synonym: N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base)
Target:
Indocyanine green
T14875
synonym: 吲哚菁绿,Foxgreen,IC Green,Cardiogreen
Target:
RFRP-1 (human) acetate(311309-25-8 free base)
TP1937L1
synonym:
Target:
KR-32568
T36569
synonym:
Target:
Forsythoside B
T3893
synonym: 连翘酯苷 B,连翘脂苷B
Target:
ML 7
T33451
synonym: ML7,ML-7
Target:
SAR296968
T70699
synonym:
Target:
RFRP-1(human) TFA
T75947
synonym:
Target:
Enrasentan
T31640
synonym: SB 217242,SB-217242,SB217242
Target:
NKH477
T16332
synonym: Colforsin dapropate hydrochloride
Target:
RFRP-1(human)
TP1937
synonym: RFRP-1 (human)
Target:
KB-R7785
T70280
synonym:
Target:
3-Iodothyronamine (hydrochloride)
T35839
synonym:
Target:
1 2 3 4
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