ca 3

CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumulation of long-chain saturated, monounsaturated, and polyunsaturated fatty acids in HT-1080 cells in vitro.HT-1080 cells lacking acetyl-CoA carboxylase 1 (ACC1), the rate-limiting enzyme in fatty acid synthesis, exhibit 5-fold resistance to CIL56 treatment, indicating ACC1 activity sensitizes cells to CIL56-induced cell death.

CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.

CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.

AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.

MDMB-PICA 3,3-dimethylbutanoic acid metabolite is a compound that is a synthetic cannabinoid metabolite. MDMB-PICA 3,3-dimethylbutanoic acid metabolite is the metabolite of MDMB-PICA.

6,10-Dimethylundeca-3,5,9-trien-2-one is a ketone with multiple double bonds, widely used in biochemical experiments and drug synthesis research.

(1R,3E,9R,10E,13S,14R)-1-(acetyloxy)-13-hydroxy-3,6,6,10,14-pentamethyl-2-oxotricyclo[10.3.0.0^{5,7}]pentadeca-3,10-dien-9-yl (2E)-4,5-dihydroxyoct-2-enoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3S,4S,5S,6R)-2-[(2-{5-hydroxy-6-[(3E,7E)-10-[3-hydroxy-6-(2-hydroxypropan-2-yl)-3-methyloxan-2-yl]-3,8-dimethyldeca-3,7-dien-1-yl]-5-methyloxan-2-yl}propan-2-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

methyl 9-hydroxy-2,6,6,11,15,18-hexamethyl-16-methylidene-5,8,14-trioxo-10,13-dioxapentacyclo[10.5.2.0^{2,7}.0^{9,18}.0^{15,19}]nonadeca-3,11-diene-19-carboxylate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3E,6E,8E,12E)-11-hydroxy-4,8,10,12-tetramethyltetradeca-3,6,8,12-tetraenoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3E,10E)-9,13-dihydroxy-3,6,6,10,14-pentamethyl-2-oxotricyclo[10.3.0.0^{5,7}]pentadeca-3,10-dien-1-yl acetate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3E,10E)-9-(acetyloxy)-1-hydroxy-3,6,6,10,14-pentamethyl-2-oxotricyclo[10.3.0.0^{5,7}]pentadeca-3,10-dien-13-yl benzoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

2,11-dimethoxy-9-(2-methylbut-3-en-2-yl)-14-(propan-2-yl)-2,13,16-triazatetracyclo[7.7.0.0^{1,13}.0^{3,8}]hexadeca-3,5,7,10-tetraene-12,15-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

14-(acetyloxy)-1,6-dihydroxy-8-(hydroxymethyl)-4,12,12,15-tetramethyl-5-oxotetracyclo[8.5.0.0^{2,6}.0^{11,13}]pentadeca-3,8-dien-13-yl 2-methylbutanoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

4-ethyl-7-hydroperoxy-10-methoxy-3,5,12-trimethyl-14-oxatetracyclo[9.2.1.0^{1,5}.0^{7,11}]tetradeca-3,9-diene-2,6,8-trione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3E,8E)-10-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4,8-dimethyldeca-3,8-dienoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(1R,3E,9R,10E,13S,14R)-9-(acetyloxy)-1-hydroxy-3,6,6,10,14-pentamethyl-2-oxotricyclo[10.3.0.0^{5,7}]pentadeca-3,10-dien-13-yl benzoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3Z)-octadeca-3,17-dien-12,14-diyne-1,2,16-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3E,7E,11E,15E)-5,9,13,17,18-pentahydroxy-4,6,8,10-tetramethyl-2-[(2E)-2-methylbut-2-en-1-yl]nonadeca-3,7,11,15-tetraenedioic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(14Z)-11-hydroxy-14-[(1H-imidazol-5-yl)methylidene]-2-methoxy-9-(2-methylbut-3-en-2-yl)-2,13,16-triazatetracyclo[7.7.0.0^{1,13}.0^{3,8}]hexadeca-3,5,7,10-tetraene-12,15-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3Z)-2,16-dihydroxyoctadeca-3,17-dien-12,14-diyn-1-yl acetate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2S,3S,4S,5S,6R)-2-[(2-{5-hydroxy-6-[(3E,7E)-10-[3-hydroxy-3-methyl-6-(2-{[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}propan-2-yl)oxan-2-yl]-3,8-dimethyldeca-3,7-dien-1-yl]-5-methyloxan-2-yl}propan-2-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

SKA-121 is a selective KCa3.1 activator (EC50s: 109 nM and 4.4 μM for KCa3.1 and KCa2.3, respectively).

NS6180 is a potent and selective KCa3.1 channel inhibitor(IC50= 9 nM). It prevents T-cell activation and inflammation.