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Search Result

Search Results for " antiprotozoal "

Targets

Parasite

41

Compounds

22

Natural Products

1

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T5052 Toltrazuril (sulfone) Toltrazuril sulfone,Ponazuril Parasite
Toltrazuril sulfone (Ponazuril) is an antiprotozoal agent that acts upon Coccidia parasites.
T21899 Misonidazole SR-1354,SR1354,Ro 7-0582 GPX
Misonidazole as a novel GPX inhibitors to cause oxidative stress in chemotherapy-resistant tumors.
T9233 Metronidazole acetic acid Antibacterial , Antibiotic , Parasite
Metronidazole (acetic acid) is a metabolite derived from Metronidazole, exhibiting mutagenic activity in bacteria. As a nitroimidazole antibiotic, amebicide, and antiprotozoal agent, Metronidazole is specifically utilize...
T1177 Sulfaquinoxaline Avicocid,Sulphaquinoxaline,Sulfabenzpyrazine Others , Antibacterial , Antibiotic , Parasite
Sulfaquinoxaline (Sulfabenzpyrazine) is an antiprotozoal agent.
T12223 Nifursemizone NF161,5-Nitro-2-furancarbaldehyde 2-ethyl semicarbazone,Etafurazone Antibiotic
Nifursemizone (Etafurazone) is an agent with antiprotozoal.
T1061 Toltrazuril BAY-i 9142,Toltrazurilo,Baycox,Toltrazurilum Antibiotic , Parasite
Toltrazuril (Toltrazurilo), an antiprotozoal agent, has effect on Coccidia parasites.
T1546 Nitazoxanide NSC 697855 Others , Influenza Virus , Parasite , Autophagy
Nitazoxanide (NSC-697855) is a synthetic benzamide with antiprotozoal activity. Nitazoxanide exerts its antiprotozoal activity by interfering with the pyruvate ferredoxin/flavodoxin oxidoreductase dependent electron tran...
T7121 Sulfaclozine Sulfachloropyrazine,Sulfachloropyrazine sodium Antibacterial , Antibiotic , Parasite
Sulfachloropyrazine sodium(Sulfachloropyrazine) is an antiprotozoal,with antibacterial and anticoccidial effects
T4269 Buparvaquone Butalex,BW 720C Antibiotic , Parasite
Buparvaquone (BW 720C) is a hydroxynaphthoquinone antiprotozoal drug related to atovaquone and parvaquone.
T1526 Nifuratel NF 113,SAP 113,Methylmercadone Antibacterial , Antibiotic , Parasite
Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.
T4218 Broxaldine Brobenzoxaldine Antibacterial , Antibiotic , Parasite , Antifungal
Broxaldine (Brobenzoxaldine) is a small molecular drug with antiprotozoal activity.
T20535 Carnidazole ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108 Antibiotic , Parasite
Carnidazole (ME-108) shows antiprotozoal activity and can be used in studies about the treatment of Trichomonas infection.
T1647 Ronidazole Ronidazol,Ridzol Antibacterial , Antibiotic , Parasite
Ronidazole (Ronidazol) is an antiprotozoal and antimicrobial agent used mainly in veterinary practice.
T0751 Furazolidone Furoxone Apoptosis , MAO , Antibacterial , Antibiotic
Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM. It is antibacterial and antiprotozoal activity,
T4982 Benznidazol Radanil,Benznidazole,Ro 71051,Ro 07-1051 Antibiotic , Parasite
Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.
T0701 Broxyquinoline Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline Antibiotic , Parasite
Broxyquinoline (5,7-Dibromo-8-hydroxyquinoline) is an antiprotozoal agent, and it can release oxygen free radicals from the water in mucous membranes.
T5325 Nifurtimox BAY-2502,BAY-A-2502 Dehydrogenase , Parasite
Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi- epimastigotes, respectively).
T1654 Pentamidine isethionate Pentamidine isethionate salt,Pentamidine diisethionate Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal
Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.
T23133 Pentamidine Phosphatase , Antibacterial , Antibiotic , Parasite , Antifungal
Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor groove of DNA, thereby interfering with DNA replication.
T0893 Tinidazole CP12574 Antibacterial , Antibiotic
Tinidazole (CP12574)a is a 5-nitroimidazole derivative with the antiprotozoal property. Although the mechanism of action has not been fully elucidated, it has been suggested that tinidazole is metabolized and yields nitr...
T17097 Tilbroquinol Others
Tilbroquinol is an antiprotozoal agent effective against amoebiasis.
T0896L Levofuraltadone Levofuraltadonum,NSC527986,NSC 527986,NSC-527986,NF-602
Levofuraltadone is an antiprotozoal and antibacterial agent.
T76257 Lefleuganan
Lefleuganan is a potent antiprotozoal agent [1] .
T63869 Anti-Trypanosoma cruzi agent-3
Anti-Trypanosoma cruzi agent-3 is an antiprotozoal agent.
T19744 Isometamidium chloride A-4180,A4180,A 4180
Isometamidium chloride is an antiprotozoal agent. It is also used in veterinary medicine.
T62210 Antileishmanial agent-10
Antileishmanial agent-10 (Compound 7h) is an antiprotozoal agent.
T24277 Hydroxy ipronidazole L-12407,Ipronidazole-OH,L12407,L 12407
L 12407 is an antiprotozoal drug of the nitroimidazole class. It is used for the treatment of histomoniasis in turkeys and for swine dysentery.
T37639 Toltrazuril sulfoxide
Toltrazuril sulfoxide, a transient intermediary metabolite of Toltrazuril, undergoes in vivo metabolism to yield the reactive toltrazuril sulfone (TZR-SO2). Toltrazuril functions as an antiprotozoal agent targeting Cocci...
T35905 Oasomycin B
Oasomycin B is a bacterial metabolite that has been found inS. baldaciiand has antiprotozoal activity.1It is active againstT. vaginalis(MIC = 62.5 μg/ml). 1.Grabley, S., Kretzschmar, G., Mayer, M., et al.Secondary metabo...
T25330 Difetarsone RP 4763,Diphetarson,RP4763,RP-4763,Difetarsonum
Difetarsone is an antiprotozoal agent. Many studies have shown that it can be particularly effective against Trichuris trichiura, commonly known as the whipworm. It has also been used to treat Entamoeba histolytica infec...
T35760 Carnaubadiol
Carnaubadiol is a triterpene that has been found in E. corollata and has antiprotozoal activities.1,2 It is active against L. infantum promastigotes and amastigotes, as well as T. cruzi trypomastigotes (IC50s = 46.2, 7.8...
T62520 Imidocarb dihydrochloride monohydrate
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).
T6769 Elaiophylin Efomycin E,Gopalamicin,Salbomycin,Azalomycin B Others , Autophagy
Elaiophylin (Salbomycin) shows antiprotozoal activity against Plasmodium falciparum K1a and Trypanosoma brucei brucei GUTat 3.1 strains with IC50 of 0.36 μM and 0.45 μM, respectively.
T63281 Antileishmanial agent-11
Antileishmanial agent-11 is a potent antileishmanial agent that acts on Leishmania brazilensis (IC50: 28.3 μM), Leishmania infantum (IC50: 24.8 μM) and T. cruzi (IC50: 13.0 μM) with outstanding antiprotozoal effect.
T62330 Antileishmanial agent-12
Antileishmanial agent-12 (compound 5a) is a potent anti-leishmanial agent with antibacterial activity against Leishmania brazilensis (IC50: 14.9 μM), Leishmania infantum (IC50: 21.3 μM) and T. cruzi (IC50. 9.3 μM). 9.3 μ...
T79415 Antiparasitic agent-18 Parasite
Antiparasitic agent-18 (compound 3a) exhibits potent and selective antiprotozoal activity, demonstrating effective inhibition of T. brucei (EC 50 =0.4 µM), T. cruzi (EC 50 =0.21 µM), and L. donovani (EC 50 =0.26 µM) [1].
T63409 Teclozan
Teclozan is an antiprotozoal agent of the benzylamine derivative class. teclozan exhibits anti-G. intestinalis effects in the intestinal lumen, interferes with phospholipid metabolism and prevents the formation of arachi...
T60468 Anti-infective agent 3
Anti-infective agent 3 is an antiprotozoal and antimycobacterial agent. Anti-infective agent 3 (compound 3l) exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.47 and ...
T60465 Anti-infective agent 2
Anti-infective agent 2 (compound 3k) is an antiprotozoal and antimycobacterial agent. Anti-infective agent 2 exhibits antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC 50 values of 0.07 and ...
T60315 Anti-infective agent 1
Anti-infective agent 1 (compound 3a) serves as a potent, selective antiprotozoal and antimycobacterial compound. It showcases antiparasitic efficacy against P. falciparum and T. brucei rhodesiense, demonstrating IC50 val...
T71261 Arsthinol
Arsthinol is an antiprotozoal agent which may have anti-cancer activity. It was found that arsthinol, a trivalent organoarsenic compound (dithiarsolane), has been active in vitro on leukemia cell lines and offers a bette...

Compounds

Toltrazuril (sulfone)
T5052
Synonym: Toltrazuril sulfone,Ponazuril
Target: Parasite
Misonidazole
T21899
Synonym: SR-1354,SR1354,Ro 7-0582
Target: GPX
Metronidazole acetic acid
T9233
Synonym:
Target: Antibacterial, Antibiotic, Parasite
Sulfaquinoxaline
T1177
Synonym: Avicocid,Sulphaquinoxaline,Sulfabenzpyrazine
Target: Others, Antibacterial, Antibiotic, Parasite
Nifursemizone
T12223
Synonym: NF161,5-Nitro-2-furancarbaldehyde 2-ethyl semicarbazone,Etafurazone
Target: Antibiotic
Toltrazuril
T1061
Synonym: BAY-i 9142,Toltrazurilo,Baycox,Toltrazurilum
Target: Antibiotic, Parasite
Nitazoxanide
T1546
Synonym: NSC 697855
Target: Others, Influenza Virus, Parasite, Autophagy
Sulfaclozine
T7121
Synonym: Sulfachloropyrazine,Sulfachloropyrazine sodium
Target: Antibacterial, Antibiotic, Parasite
Buparvaquone
T4269
Synonym: Butalex,BW 720C
Target: Antibiotic, Parasite
Nifuratel
T1526
Synonym: NF 113,SAP 113,Methylmercadone
Target: Antibacterial, Antibiotic, Parasite
Broxaldine
T4218
Synonym: Brobenzoxaldine
Target: Antibacterial, Antibiotic, Parasite, Antifungal
Carnidazole
T20535
Synonym: ME 108,NSC293873,NSC 293873,ME-108,NSC-293873,ME108
Target: Antibiotic, Parasite
Ronidazole
T1647
Synonym: Ronidazol,Ridzol
Target: Antibacterial, Antibiotic, Parasite
Furazolidone
T0751
Synonym: Furoxone
Target: Apoptosis, MAO, Antibacterial, Antibiotic
Benznidazol
T4982
Synonym: Radanil,Benznidazole,Ro 71051,Ro 07-1051
Target: Antibiotic, Parasite
Broxyquinoline
T0701
Synonym: Dibromohydroxyquinoline,5,7-Dibromo-8-hydroxyquinoline
Target: Antibiotic, Parasite
Nifurtimox
T5325
Synonym: BAY-2502,BAY-A-2502
Target: Dehydrogenase, Parasite
Pentamidine isethionate
T1654
Synonym: Pentamidine isethionate salt,Pentamidine diisethionate
Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal
Pentamidine
T23133
Synonym:
Target: Phosphatase, Antibacterial, Antibiotic, Parasite, Antifungal
Tinidazole
T0893
Synonym: CP12574
Target: Antibacterial, Antibiotic
Tilbroquinol
T17097
Synonym:
Target: Others
Levofuraltadone
T0896L
Synonym: Levofuraltadonum,NSC527986,NSC 527986,NSC-527986,NF-602
Target:
Lefleuganan
T76257
Synonym:
Target:
Anti-Trypanosoma cruzi agent-3
T63869
Synonym:
Target:
Isometamidium chloride
T19744
Synonym: A-4180,A4180,A 4180
Target:
Antileishmanial agent-10
T62210
Synonym:
Target:
Hydroxy ipronidazole
T24277
Synonym: L-12407,Ipronidazole-OH,L12407,L 12407
Target:
Toltrazuril sulfoxide
T37639
Synonym:
Target:
Oasomycin B
T35905
Synonym:
Target:
Difetarsone
T25330
Synonym: RP 4763,Diphetarson,RP4763,RP-4763,Difetarsonum
Target:
Carnaubadiol
T35760
Synonym:
Target:
Imidocarb dihydrochloride monohydrate
T62520
Synonym:
Target:
Elaiophylin
T6769
Synonym: Efomycin E,Gopalamicin,Salbomycin,Azalomycin B
Target: Others, Autophagy
Antileishmanial agent-11
T63281
Synonym:
Target:
Antileishmanial agent-12
T62330
Synonym:
Target:
Antiparasitic agent-18
T79415
Synonym:
Target: Parasite
Teclozan
T63409
Synonym:
Target:
Anti-infective agent 3
T60468
Synonym:
Target:
Anti-infective agent 2
T60465
Synonym:
Target:
Anti-infective agent 1
T60315
Synonym:
Target:
Arsthinol
T71261
Synonym:
Target:
Cat No. Product Name Synonyms Targets
T1079 Metronidazole Flagyl,Metronidazol,Anagiardil Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T7909 α-Terpinene Others , Parasite , Antifungal
α-Terpinene is a terpenoid,has acaricidal, antiprotozoal, and antioxidant properties
T1556 Ornidazole Tiberal,Ornidazolum,NSC 95075,Ro 7-0207 Antibacterial , Antibiotic , Parasite
Ornidazole (Tiberal) is a nitroimidazole antiprotozoal agent used in ameba and trichomonas infections. It is partially plasma-bound and also has radiation-sensitizing action.
T1033 Monensin sodium salt Sodium Monensin,Monensin A sodium salt Sodium Channel , Antibacterial , Antibiotic
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion
TN6930 5-Desmethylsinensetin Others
5-Desmethylsinensetin is a natural product.
T1304 Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride ribosome , Antibacterial , Antibiotic
Chlortetracycline Hydrochloride is a tetracycline with broad-spectrum antibacterial and antiprotozoal activity. Chlortetracycline hydrochloride (Isphamycin) is bacteriostatic and inhibits bacterial protein synthesis by b...
T2S1792 Lycobetaine Ungeremine Antibacterial
1. Lycobetaine (Ungeremine) is a potential biofungicide against Penicillium roqueforti and Aspergillus niger.2. Lycobetaine have strong antibacterial activity against Flavobacterium columnare . 3. Lycobetaine effectively...
TN3177 6-Methyl-5,6-dihydropyran-2-one Antifection
6-Methyl-5,6-dihydropyran-2-on is bactericidal,and antiprotozoal agents.
TN4933 Sahandol Antifection
Sahandol shows antiprotozoal activity against P. falciparum and T. brucei rhodesiense.
T1033L Monensin Elancoban,Rumensin
Monensin is an antiprotozoal agent produced by Streptomyces cinnamonensis. It has an inhibitory effect on the Wnt/β-catenin signaling cascade. Monensin is a prospective anticancer drug for the therapy of neoplasia with d...
T75575 Geranin A
Geranin A, an A-type proanthocyanidin, can be isolated from the antiprotozoal extract of Geranium niveum [1].
TN2798 20-Deoxocarnosol ROS , Antifection
20-Deoxocarnosol has antioxidant activity of measuring the decay of the radical cation diphenyl-picrylhydrazyl (DPPH).It also exhibits non-specific antiprotozoal activity due to high cytotoxicity.
T40643 Prodigiosin hydrochloride Prodigiosine hydrochloride
Prodigiosin hydrochloride, a red pigment, is a bioactive secondary metabolite produced by bacteria. It exhibits potent proapoptotic activity and functions as an inhibitor of the Wnt/β-catenin pathway. Additionally, this ...
TN3276 8-Epixanthatin Antifection
8-Epixanthatin, a light-induced growth inhibitor, mediates the phototropic curvature in sunflower (Helianthus annuus) hypocotyls, it can induce germination of O. cumana at nano- to micromolar concentrations. 8-Epixanthat...
TN3627 Chalepensin ATPase , NADPH-oxidase , P450 , Antifection
Chalepensin behaves as an energy transfer inhibitor at low concentration, it inhibits multiple P450s and that epoxidation activity is crucial for the potential drug interaction through mechanism-based inhibition. Chalepe...
T27564 Hymenidin 5-HT Receptor
Hymenidin, an alkaloid isolated from the Okinawan sponge Hymeniacidon sp. is a 5-hydroxytryptaminergic receptor antagonist and voltage-gated potassium channel inhibitor with potential antiprotozoal effects.It selectively...
T82716 Cis-Melilotoside
Cis-Melilotoside, a derivative of o-coumaric acid, exhibits potent antioxidant properties and demonstrates moderate antiprotozoal activity against T. cruzi, with an inhibitory concentration (IC 50) of 78.2 μg/mL [1] [2].
T72916 Justicidin B
Justicidin B, a potent lignan, exhibits anticancer and proapoptotic properties, additionally serving as a bone resorption inhibitor. This compound demonstrates robust antiviral, fungicidal, and antiprotozoal effects, alo...
T20636 Latrunculin B LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644 Antifungal
Latrunculin B, an alkaloid from the Red Sea sponge, is an actin polymerization inhibitor with antifungal and antiprotozoal activity.Latrunculin B modulates the electrophysiological characteristics of the pulmonary veins ...
T35758 Butyrolactone V
Butyrolactone V is a fungal metabolite that has been found in A. terreus and has antiprotozoal, antioxidant, and anticancer activities.1,2,3 It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amaz...
TN4683 Nyasol ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt , Antifection
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antif...
T35751 Violacein
Violacein is a bacterial metabolite originally isolated from C. violaceum that has antibacterial and antiprotozoal activities.[1] [2] It is produced by C. violaceum as a purple pigment in response to N-hexanoyl homoserin...

Natural Products

Metronidazole
T1079
Synonym: Flagyl,Metronidazol,Anagiardil
Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection
α-Terpinene
T7909
Synonym:
Target: Others, Parasite, Antifungal
Ornidazole
T1556
Synonym: Tiberal,Ornidazolum,NSC 95075,Ro 7-0207
Target: Antibacterial, Antibiotic, Parasite
Monensin sodium salt
T1033
Synonym: Sodium Monensin,Monensin A sodium salt
Target: Sodium Channel, Antibacterial, Antibiotic
5-Desmethylsinensetin
TN6930
Synonym:
Target: Others
Chlortetracycline hydrochloride
T1304
Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride
Target: ribosome, Antibacterial, Antibiotic
Lycobetaine
T2S1792
Synonym: Ungeremine
Target: Antibacterial
6-Methyl-5,6-dihydropyran-2-one
TN3177
Synonym:
Target: Antifection
Sahandol
TN4933
Synonym:
Target: Antifection
Monensin
T1033L
Synonym: Elancoban,Rumensin
Target:
Geranin A
T75575
Synonym:
Target:
20-Deoxocarnosol
TN2798
Synonym:
Target: ROS, Antifection
Prodigiosin hydrochloride
T40643
Synonym: Prodigiosine hydrochloride
Target:
8-Epixanthatin
TN3276
Synonym:
Target: Antifection
Chalepensin
TN3627
Synonym:
Target: ATPase, NADPH-oxidase, P450, Antifection
Hymenidin
T27564
Synonym:
Target: 5-HT Receptor
cis-Melilotoside
T82716
Synonym:
Target:
Justicidin B
T72916
Synonym:
Target:
Latrunculin B
T20636
Synonym: LAT-B,LATB,NSC 339663,NSC339663,NSC-339663,LAT B,INS115644
Target: Antifungal
Butyrolactone V
T35758
Synonym:
Target:
Nyasol
TN4683
Synonym:
Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt, Antifection
Violacein
T35751
Synonym:
Target:

Recombinant Proteins

Species：
Canine (1)
Expression System：
E. coli (1)
Tag：
C-His (1)
Cat No. Product Name Species Expression System
TMPK-01308 TAG-72 Protein, Canine, Recombinant (His) Canine E. coli
The guanine-N7 methyltransferase domain of vaccinia virus mRNA capping enzyme is a heterodimer composed of a catalytic subunit and a stimulatory subunit. Cap (guanine-N7) methylation is an essential step in eukaryal mRNA...
Cat No. Product Name
L1100 Protease Inhibitor Library

344 compounds
A unique collection of 344 protease and proteasome inhibitors for research in chemical genomics, and drug screening;

Libraries

Protease Inhibitor Library
L1100
Compounds: 344
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