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ampk α1β1γ1

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    9
    TargetMol | Inhibitors_Agonists
AMPK-α1β1γ1 activator 1
T831251943510-86-8
AMPK-α1β1γ1 activator 1 (M1), an acyl glucuronide metabolite derived from an Indole-3-carboxylic Acid-based AMPK activator, selectively activates the β1 isoforms of human AMPK with an EC50 of 38.1 nM through direct binding to the human AMPK α1β1γ1 isoform; it is utilized in diabetic nephropathy research [1].
  • Inquiry Price
8-10 weeks
Size
QTY
EX229
Compound 991, C991
TQ00281219739-36-2
EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.
  • $31
In Stock
Size
QTY
ZLN024
T13411723249-01-2
ZLN024 is an activator of AMPK allosteric. ZLN024 allosterically stimulates active AMPK heterotrimers and the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).
  • $89
In Stock
Size
QTY
pf-06679142
PF-6679142, PF6679142, PF06679142, PF 6679142
T246221467059-66-0
PF-06679142 is an effective AMPK activator. PF-06679142 exhibited robust activation of AMPK in rat kidneys as well as desirable oral absorption.
  • $1,820
8-10 weeks
Size
QTY
PF-249
PF-06685249, PF 06685249, PF06685249
T246261467059-70-6
PF-249 (PF-06685249) is a β1-selective AMPK with an EC50 of 12 nM for AMPK α1β1γ1 and can be used in studies about diabetic nephropathy.
  • $41
In Stock
Size
QTY
pf-739
T246281852452-14-2
PF-739 is an AMPK agonist that has been shown to activate AMPK in hepatocytes and skeletal muscle.
  • $1,670
6-8 weeks
Size
QTY
ZLN 024 hydrochloride
T411621883548-91-1
ZLN 024 hydrochloride is an AMPK allosteric activator and stimulates the inactive α1 subunit truncations α1 (1-394) and α1 (1-335) but not α1 (1-312).
  • $44
In Stock
Size
QTY
PF-06409577
PF 06409577
T44271467057-23-3
PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).
  • $38
In Stock
Size
QTY
ampk activator 8
T631771852451-96-7
AMPK activator 8 (Compound 2) is an AMP-activated protein kinase (AMPK) activator that acts on rAMPK α1β1γ1 (EC50: 11 nM), rAMPK α2β1γ1 (EC50: 27 nM), rAMPK α1β2γ1 (EC50: 4 nM), rAMPK α2β2 AMPK activator 8 can be used to study type 2 diabetes.
  • $1,520
6-8 weeks
Size
QTY