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Anti-ENPP3/CD203c Antibody (AGS-16C3F antibody) is a human antibody expressed in CHO cells, designed to target ENPP3/CD203c, widely applied in research and experiments in the field of life sciences.

AGS-16C3F is an antibody-drug conjugate (ADC) targeting ENPP3 (also known as CD203c). This product consists of a humanized IgG1 monoclonal antibody against ENPP3 conjugated to the microtubule inhibitor monomethyl auristatin F (MMAF) via a non-cleavable linker. AGS-16C3F functions by specifically binding to ENPP3 on the surface of tumor cells, undergoing internalization, and releasing MMAF intracellularly to induce cell cycle arrest and apoptosis. It exhibits potent anti-tumor and anti-proliferative activity in ENPP3-expressing metastatic renal cell carcinoma (mRCC) and systemic mastocytosis.

BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.

Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

Sertindole (Lu 23-174) is an atypical antipsychotic that binds to dopamine D2 receptors and serotonin (5-HT) receptor subtypes 5-HT1D, 5-HT2A, and 5-HT2C, with Kds of 2.7, 20, 0.14, and 6 nM, respectively.

Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.

BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.

Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.

AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).

ASG-5ME is a drug-antibody coupling targeting SLC44A4 that shows anti-tumor activity in xenograft models and may be used to study pancreatic and gastric cancer.

Anti-SLC44A4 Antibody is an antibody inhibitor targeting SLC44A4, suitable for synthesizing the ADC molecule ASG-5ME.

AGS-67E is a CD37-targeted antibody-drug conjugate (ADC) consisting of a humanized mAb conjugated to MMAE. It binds specifically to CD37 on lymphoma cells and releases the toxin upon internalization, inducing apoptosis.

AGS-009 is a humanized monoclonal neutralizing antibody that targets IFN-α. It significantly reduces the number of activated lymphocytes (e.g., CD4+ and CD8+ T cells as well as B cells) in a SIV-infected rhesus monkey model. AGS-009 is applicable to research on autoimmune diseases such as systemic lupus erythematosus (SLE) and HIV infection.

AGS1286 sodium is an organosulfur compound. It has been used as a model compound to study the effects of sulfur-containing compounds on enzymatic activities and metabolic pathways. It has also been used to study the effects of sulfur-containing compounds on the regulation of bacterial growth and gene expression.

Anti-FLT3 Antibody (AGS62P) is an ADC antibody targeting FLT3 for research in acute myeloid leukemia.

Bragsin1 is a potent and selective and noncompetitive ArfGEF BRAG2 inhibitor, inhibits Arf GTPase activation(IC50 : 3 μM),and with anti-cancer activity.

Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.

Nagstatin is an inhibitor of N-acetyl-beta-D-glucosaminidase and is produced by Streptomyces amakusaensis MG846-fF3.

Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and induces apoptosis.

Ursolic acid (Prunol) is a natural product, a pentacyclic triterpene carboxylic acid extracted from Rhododendron caprifolium. Ursolic acid has anti-tumor, anti-inflammatory, anti-bacterial and hypoglycemic activities.

Silver sulfadiazine (Dermazin) is a sulfonamide-based topical agent with antibacterial and antifungal activity.

GSK126 (GSK2816126A) is a excellently specific EZH2 methyltransferase inhibitor ( IC50=9.9 nM).

Danshenxinkun A is a natural product isolated from Salvia miltiorrhiza (Tanshen) exhibiting neuraminidase inhibitory activity with an IC50 of 39.5 mg/L.

Evatanepag, also known as CP-533536, is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing.