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Search Results for " ugt "

Targets

14

Compounds

6

Natural Products

9

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T40046 UGT8-IN-1 UGT8-IN-1
UGT8-IN-1 is a brain-permeable and orally-active inhibitor that specifically targets the ceramide galactosyltransferase enzyme (UGT8). By inhibiting UGT8, this compound has the potential to be employed in research pertai...
T35845 (R,S)-Carvedilol Glucuronide
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the...
T37484 1-Salicylate Glucuronide
1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and ...
T35952 All-trans Retinoyl β-D-Glucuronide
all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo admin...
T37117 Etodolac Acyl Glucuronide
Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isof...
T37852 Chlorzoxazone N-Glucuronide
Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone . Chlorzoxazone N-glucuronide is formed via glucuronidation of chlorzoxazone by the UDP-glucuronosyltransferase (UGT) iso...
T36826 Acetaminophen Glucuronide (sodium salt)
Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A...
T62328 Cabotegravir sodium
Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less li...
T36071 Silodosin Glucuronide (sodium salt)
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to r...
T35619 Dapagliflozin-3-O-β-D-Glucuronide
Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metab...
T35939 Dabigatran Acyl-β-D-Glucuronide
Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabol...
T37005 Estriol 3-β-D-Glucuronide (sodium salt)
Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membr...
T36794 Dolutegravir O-β-D-Glucuronide
Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized ...
T83873 Dabigatran Acyl-β-D-Glucuronide TFA Dabigatran β-1-O-Acyl Glucuronide
Dabigatran acyl-β-D-glucuronide, an active metabolite of the thrombin inhibitor dabigatran, is synthesized predominantly through the action of the UDP-glucuronosyltransferase isoform UGT2B15. This compound, at a concentr...
Cat No. Product Name Synonyms Targets
T7995 α-Angelica lactone Alpha-Angelica Lactone Others , GST
α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization.
T3880 Silydianin Silidianin Phosphatase
Silydianin (Silidianin) exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exerts inhibition of OATP2B1 (unknown origin) expre...
T2565 Hesperetin Apoptosis , p38 MAPK , 5-HT Receptor , Autophagy , TGF-beta/Smad
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges.
T3824 Jaceosidin Apoptosis , BCL , COX , UGT
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...
TN5356 Epiglobulol
Epiglobulol shows antibacterial activities, it can strongly inhibit the growth of foodborne microorganisms. Epiglobulol can inhibit the recombinant human UDP-glucuronosyltransferase (UGT) 2B7, it may serve as valuable le...
T12667 (Rac)-Hesperetin Others
(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits potent inhibitory effects against human UGT activity, making it a broad-spectrum inhibitor. Furthermore,...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPH-00112 UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc) Arabidopsis thaliana Baculovirus
UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc) is expressed in Baculovirus.
TMPH-00090 UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) Arabidopsis thaliana E. coli
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...
TMPH-00111 UGT72E2 Protein, Arabidopsis thaliana, Recombinant (E. coli, His & Myc) Arabidopsis thaliana E. coli
UGT72E2 Protein, Arabidopsis thaliana, Recombinant (E. coli, His & Myc) is expressed in E. coli.
TMPH-00113 UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana E. coli
UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli.
TMPH-00091 UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) Arabidopsis thaliana Yeast
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve...
TMPH-00116 UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) Arabidopsis thaliana Yeast
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) is expressed in Yeast.
TMPH-00114 UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana Baculovirus
UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in Baculovirus.
TMPH-00115 UGT89C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) Arabidopsis thaliana E. coli
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) is expressed in E. coli.
TMPH-00110 UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) Arabidopsis thaliana E. coli
UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli.
TargetMol