T40046 |
UGT8-IN-1
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UGT8-IN-1 |
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UGT8-IN-1 is a brain-permeable and orally-active inhibitor that specifically targets the ceramide galactosyltransferase ... |
TMP-03899 |
Human UGT3A2, His Tag
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TMP-03896 |
Human UGT3A1, Fc Tag
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TMP-03898 |
Human UGT3A2, Fc Tag
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TMP-03897 |
Human UGT3A1, His Tag
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TMP-03895 |
Human UGT2A3, His Tag
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TMP-03894 |
Human UGT2A3, Fc Tag
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T7995 |
α-Angelica lactone
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α-当归内酯,当归内酯,Alpha-Angelica Lactone |
Others
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GST
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Alpha-Angelica Lactone 是一种乙烯基亲核试剂,也是一种天然存在的抗癌剂。它可以得到手性的 δ-氨基 γ,γ-二取代丁烯醇内酯羰基衍生物,并在 γ-碳上表现出亲电子俘获。它通过选择性增强谷胱甘肽-S-硫转移酶 (GST)... |
T3880 |
Silydianin
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水飞蓟宁,Silidianin |
Phosphatase
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Silydianin 是一种水飞蓟的活性成分,具有抗胶原酶和抗弹性酶作用,对氧化产物的体外产生和释放具有抑制作用 。它是一种天然蛋白酪氨酸磷酸酶 1B 抑制剂,其IC50=17.38 μM。 |
T2565 |
Hesperetin
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5-HT Receptor
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p38 MAPK
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Autophagy
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Apoptosis
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TGF-beta/Smad
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Hesperetin 是一种天然黄烷酮类物质,是人UGT 的广谱抑制剂,可诱导凋亡。 |
T3824 |
Jaceosidin
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Apoptosis
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BCL
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COX
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UGT
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Jaceosidin 是从毛莲蒿中得到的一种黄酮类天然产物,可激活Bax,下调 Mcl-1 和 c-FLIP 的表达,诱导癌细胞凋亡。它能够降低炎性因子水平,激活 NF-κB,抑制COX-2的表达,具有抗癌和抗炎作用。 |
T35845 |
(R,S)-Carvedilol Glucuronide
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(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carve... |
TN5356 |
Epiglobulol
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Epiglobulol shows antibacterial activities, it can strongly inhibit the growth of foodborne microorganisms. Epiglobulol ... |
T35952 |
All-trans Retinoyl β-D-Glucuronide
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all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase ... |
T12667 |
(Rac)-Hesperetin
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Others
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(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits pote... |
T37117 |
Etodolac Acyl Glucuronide
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Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor... |
T37484 |
1-Salicylate Glucuronide
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1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by t... |
T62328 |
Cabotegravir sodium
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Cabotegravir sodium 是一种 HIV 整合酶的高效抑制剂,能够作用于 HIVADA (IC50: 2.5 nM)。Cabotegravir sodium 主要由尿苷二磷酸葡萄糖醛酸转移酶 (UGT) 1A1 代谢,与其他抗... |
T37852 |
Chlorzoxazone N-Glucuronide
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Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone . Chlorzoxazone N-glu... |
T36826 |
Acetaminophen Glucuronide (sodium salt)
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Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed ... |