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Cat No. | Product Name | Synonyms | Targets |
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T40046 | UGT8-IN-1 | UGT8-IN-1 | |
UGT8-IN-1 is a brain-permeable and orally-active inhibitor that specifically targets the ceramide galactosyltransferase enzyme (UGT8). By inhibiting UGT8, this compound has the potential to be employed in research pertai... | |||
T35845 | (R,S)-Carvedilol Glucuronide | ||
(R,S)-Carvedilol glucuronide is a racemic mixture of the carvedilol metabolites (R)-carvedilol glucuronide and (S)-carvedilol glucuronide. (R)-Carvedilol glucuronide is formed via glucuronidation of (R)-carvedilol by the... | |||
T37484 | 1-Salicylate Glucuronide | ||
1-Salicylate glucuronide is a metabolite of salicylic acid and aspirin .1It is formed from salicylic acid primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A9 but also by a variety of other UGT isoforms and ... | |||
T35952 | All-trans Retinoyl β-D-Glucuronide | ||
all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system. It is rapidly converted to all-trans retinoic acid following in vitro or in vivo admin... | |||
T37117 | Etodolac Acyl Glucuronide | ||
Etodolac acyl glucuronide is a phase II metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor etodolac .1It is formedviaglucuronidation of etodolac by the UDP-glucuronosyltransferase (UGT) isof... | |||
T37852 | Chlorzoxazone N-Glucuronide | ||
Chlorzoxazone N-glucuronide is a phase II metabolite of the skeletal muscle relaxant chlorzoxazone . Chlorzoxazone N-glucuronide is formed via glucuronidation of chlorzoxazone by the UDP-glucuronosyltransferase (UGT) iso... | |||
T36826 | Acetaminophen Glucuronide (sodium salt) | ||
Acetaminophen glucuronide is an inactive metabolite of the analgesic and antipyretic agent acetaminophen . It is formed via glucuronidation of acetaminophen by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A6, UGT1A... | |||
T62328 | Cabotegravir sodium | ||
Cabotegravir sodium is a potent inhibitor of HIV integrase and is able to act on HIVADA (IC50: 2.5 nM). cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1 and is less li... | |||
T36071 | Silodosin Glucuronide (sodium salt) | ||
Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to r... | |||
T35619 | Dapagliflozin-3-O-β-D-Glucuronide | ||
Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metab... | |||
T35939 | Dabigatran Acyl-β-D-Glucuronide | ||
Dabigatran acyl-β-D-glucuronide is a major active metabolite of the thrombin inhibitor dabigatran . The prodrug of dabigatran, dabigatran etexilate , is hydrolyzed by plasma esterases to form dabigatran, which is metabol... | |||
T37005 | Estriol 3-β-D-Glucuronide (sodium salt) | ||
Estriol 3-β-D-glucuronide is a metabolite of estriol . It is formed from estriol by the UDP-glucuronosyltransferase (UGT) isoform UGT1A10. Estriol 3-β-D-glucuronide binds to basolateral and canalicular liver plasma membr... | |||
T36794 | Dolutegravir O-β-D-Glucuronide | ||
Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized ... | |||
T83873 | Dabigatran Acyl-β-D-Glucuronide TFA | Dabigatran β-1-O-Acyl Glucuronide | |
Dabigatran acyl-β-D-glucuronide, an active metabolite of the thrombin inhibitor dabigatran, is synthesized predominantly through the action of the UDP-glucuronosyltransferase isoform UGT2B15. This compound, at a concentr... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T7995 | α-Angelica lactone | Alpha-Angelica Lactone | Others , GST |
α-Angelica lactone has cardiotonic activity, may exert their effects by providing an increased contraction-dependent calcium pool to be released upon systolic depolarization. | |||
T3880 | Silydianin | Silidianin | Phosphatase |
Silydianin (Silidianin) exerts inhibition of UGT in human liver. Silydianin exerts inhibition of OATP1B1, OATP1B3 (unknown origin) expressed in HEK293 cells. Silydianin exerts inhibition of OATP2B1 (unknown origin) expre... | |||
T2565 | Hesperetin | Apoptosis , p38 MAPK , 5-HT Receptor , Autophagy , TGF-beta/Smad | |
Hesperetin belongs to the flavanone class of flavonoids. Hesperetin, in the form of its glycoside hesperidin, is the predominant flavonoid in lemons and oranges. | |||
T3824 | Jaceosidin | Apoptosis , BCL , COX , UGT | |
Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway... | |||
TN5356 | Epiglobulol | ||
Epiglobulol shows antibacterial activities, it can strongly inhibit the growth of foodborne microorganisms. Epiglobulol can inhibit the recombinant human UDP-glucuronosyltransferase (UGT) 2B7, it may serve as valuable le... | |||
T12667 | (Rac)-Hesperetin | Others | |
(Rac)-Hesperetin is the racemate form of of Hesperetin. Hesperetin is a natural flavanone compound, and it exhibits potent inhibitory effects against human UGT activity, making it a broad-spectrum inhibitor. Furthermore,... |
Cat No. | Product Name | Species | Expression System |
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TMPH-00112 | UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc) | Arabidopsis thaliana | Baculovirus |
UGT72E2 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His & Myc) is expressed in Baculovirus. | |||
TMPH-00090 | UGT71C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) | Arabidopsis thaliana | E. coli |
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve... | |||
TMPH-00111 | UGT72E2 Protein, Arabidopsis thaliana, Recombinant (E. coli, His & Myc) | Arabidopsis thaliana | E. coli |
UGT72E2 Protein, Arabidopsis thaliana, Recombinant (E. coli, His & Myc) is expressed in E. coli. | |||
TMPH-00113 | UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) | Arabidopsis thaliana | E. coli |
UGT78D1 Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli. | |||
TMPH-00091 | UGT71C1 Protein, Arabidopsis thaliana, Recombinant (Baculovirus, His) | Arabidopsis thaliana | Yeast |
Possesses quercetin 7-O-glucosyltransferase and 3'-O-glucosyltransferase activities in vitro. Also active in vitro on benzoates and benzoate derivatives. Glucosylates other secondary metabolites in vitro like trans-resve... | |||
TMPH-00116 | UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) | Arabidopsis thaliana | Yeast |
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (Yeast, His) is expressed in Yeast. | |||
TMPH-00114 | UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | Baculovirus |
UGT88A1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPH-00115 | UGT89C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) | Arabidopsis thaliana | E. coli |
UGT89C1 Protein, Arabidopsis thaliana, Recombinant (E. coli, His) is expressed in E. coli. | |||
TMPH-00110 | UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) | Arabidopsis thaliana | E. coli |
UGT72B1 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli. |