RNase

DEPC (Diethyl pyrocarbonate) is a potent and irreversible RNase inhibitor containing histidine residues.DEPC can be used to prevent RNA enzyme degradation by modifying histidine residues with carboxylation resulting in enzyme inactivation. DEPC showed inhibitory effect on the central chemical sensitivity of rabbits. DEPC modified His, Tyr, Ser and Thr residues.

DEPC-Treated Water is ultra-pure water that has been sterilized at high temperatures and pressure. It is free from nucleases, preventing contamination by nonspecific endonucleases and exonucleases, while not affecting RNase activity.