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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8720 | PRX-07034 hydrochloride | PRX-07034 | 5-HT Receptor |
PRX-07034 hydrochloride is a selective antagonist of 5-HT6 receptor. It has cognition and memory-enhancing properties and potently decreases food intake and body weight in rodents. PRX-07034 hydrochloride is both a poten... | |||
T16669 | PRX-08066 | 5-HT Receptor | |
PRX-08066 is a selective 5-hydroxytryptamine receptor 2B (5-HT2BR, IC50= 3.4 nM) antagonist that induces selective vasodilation of pulmonary arteries. | |||
T16265 | Naluzotan | PRX 00023 | EGFR , 5-HT Receptor |
Naluzotan(PRX 00023) is a novel and potent 5-HT1A agonist with IC50 and Ki values of approximately 20 nM and 5.1 nM, respectively.Naluzotan is a potent hERG K+ channel blocker with an IC50 value of 3800 nM.Naluzotan exhi... | |||
T77751 | Imaprelimab | PRX-003 | Others |
Imaprelimab (PRX-003) is a humanized IgG1 κmonoclonal antibody against melanoma cell adhesion molecule (MCAM). Imaprelimab has antitumor activity and can be used to study inflammation, tumors, and psoriasis. | |||
T68113 | Naluzotan hydrochloride | PRX 00023 hydrochloride | EGFR , 5-HT Receptor |
Naluzotan hydrochloride (PRX 00023 hydrochloride) is a hERG K+ channel blocker with an IC50 value of 3800 nM and is commonly used in the study of anxiety and depression.Naluzotan hydrochloride is also a novel, potent, an... | |||
T6959 | PRX-08066 Maleic acid | 5-HT Receptor | |
PRX-08066 Maleic acid is a selective 5-HT2B receptor antagonist with IC50 of 3.4 nM, prevents the severity of pulmonary arterial hypertension in the MCT rat model. Phase 2. | |||
T21229 | Pirenoxine | Catalin,PRX | |
Pirenoxine is an agent with anti-cataractogenesis activity by interacting with calcium ions or selenite which could lead to the formation of lens cataract. | |||
T29115 | VRX 03011 Potassium salt | PRX-03140,PRX3140,NTC942,NTC-942,PRX-3140,PRX03140 | |
VRX 03011, a 5-HT4 partial agonist, is used potentially for the treatment of Alzheimer's disease. | |||
T80966 | Topsalysin | PRX-302 | |
Topsalysin, a prostate-specific antigen (PSA)-activated protoxin, comprises a synthetic proaerolysin fusion protein targeting human prostate-specific antigen. This compound has demonstrated tumor-suppressive effects in a... | |||
T12565 | PRX933 hydrochloride | BVT-933 hydrochloride,GW876167 hydrochloride | 5-HT Receptor |
PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment. | |||
T80920 | Tulinercept | OPRX-106,TNFR-Fc,PRX-106 | |
Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1]. | |||
T27518 | GW-876167 | PRX-00933,PNU-183933,GW876167,BVT933,BVT-933 | |
GW-876167, a 5-HT2C agonist, is used potentially for the treatment of obesity and glaucoma. | |||
T12104 | MRGPRX1 agonist 1 | Others | |
MRGPRX1 agonist 1 is a highly potent MRGPRX1 (Mas-related G-protein-coupled receptor X1)agonist(EC50 of 50 nM). | |||
T63812 | MrgprX2 antagonist-8 | Others | |
MrgprX2 antagonist-8 is an MrgprX2 antagonist that can be used to study inflammatory diseases. | |||
T40271 | MrgprX2 antagonist-3 | MrgprX2 antagonist-3 | |
MrgprX2 antagonist-3 is a potent inhibitor of MrgprX2. It holds promising potential for investigating skin inflammatory disorders. | |||
T40273 | MrgprX2 antagonist-2 | MrgprX2 antagonist-2 | |
MrgprX2 antagonist-2 is a potent antagonist of MrgprX2. It holds potential for investigating skin inflammatory disorders. | |||
T80167 | αC-Conotoxin PrXA | αC-PrXA | |
αC-Conotoxin PrXA is a neurotoxic paralytic peptide acting as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR), exhibiting inhibitory constants (IC50) of 1.8 nM for the adult α1β1εδ subtype and 3.... | |||
T60466 | MRGPRX1 agonist 2 | ||
MRGPRX1 agonist 2 (compound 1a) is a potent positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MRGPRX1) with an EC 50 value of 0.48 μM. MRGPRX1 agonist 2 has the potential to be used in neuropath... | |||
T63766 | MrgprX2 antagonist-7 | ||
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation. | |||
T40270 | MrgprX2 antagonist-1 | MrgprX2 antagonist-1 | |
MrgprX2 antagonist-1, is a novel MrgprX2 antagonist compound. It exhibits potential for exploration in studying cutaneous inflammatory disorders. |