T21874 |
CID 2745687
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GPR
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CID 2745687 是可逆的、特异性 GPR35竞争性拮抗剂(Ki:12.8 nM)。 |
T8329 |
AR 231453
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GPR
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AR 231453 是一种口服具有活性的、特异性的 GPR119激动剂。它能够刺激细胞增殖,改善胰岛 β 细胞的功能。 |
T3433 |
TUG-891
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TUG891,TUG 891 |
GPR
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TUG891 是一种选择性的长链游离脂肪酸受体 4 (FFA4/GPR120) 的激动剂。 |
T10843 |
CMF019
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Apelin receptor
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CMF019 是一种有效的小分子 Apelin receptor (APJ) 激动剂,具有 G protein 偏向性。 CMF019 在人,大鼠和小鼠中与 APJ 结合的 pKi 值分别为 8.58、8.49 和 8.71。CMF-019... |
T9146 |
Ms48107
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Benzenemethanol, 2-[4-amino-6-[[(4-phenoxyphenyl)methyl]amino]-1,3,5-triazin-2-yl]-3-fluoro- |
Others
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MS48107 是 G 蛋白偶联受体 68 (GPR68) 的选择性正变构调节剂,对GPR68的选择性高于密切相关的神经递质转运蛋白,质子 GPCR 和 hERG 离子通道。它可以穿越过小鼠的血脑屏障。 |
T50088 |
N-phenylthiophene-2-carboximidamide
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Others
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N-phenylthiophene-2-carboximidamide 是一种噻吩衍生物类的有机化合物,已被用于合成各种有机化合物,包括药物和农用化学品。它还可以作为蛋白酪氨酸激酶(PTKs)的抑制剂和G 蛋白偶联受体(GPCR)的配体发挥... |
T27428 |
GP-1681
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GP 1681,GP1681 |
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GP-1681, a G-protein coupled receptor (GPCR) agonist, is used potentially for the treatment of influenza infection. |
T26962 |
CBP-307
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CBP307 |
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CBP-307 is a selective second generation S1P1 (a G-protein coupled receptor -GPCR) modulator. |
T10363 |
Arazine
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N-Acetyl-S-farnesyl-L-cysteine |
Others
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Arazine 可以成为异戊二烯基半胱氨酸甲基转移酶的底物通过与异戊二烯化 G 蛋白或其受体位点竞争。 Arazine 是 G 蛋白和 GPCR 信号传导的细胞渗透性调节剂。 |
T11044 |
Dihydromunduletone
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DHM |
GPR
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Dihydromunduletone (DHM) is a carotenoid derivative and selective strong adhesion G protein-coupled receptor (aGPCR) (GP... |
TN5580 |
Rediocide A
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Rediocide A, an insecticide, can inhibit calcium mobilization in Drosophila G-protein- coupled receptors (GPCR)s other t... |
T73005 |
PF-07054894
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PF-07054894 是一种有效的 CCR6拮抗剂。 PF-07054894 靶向 G 蛋白偶联受体 (GPCR)。 PF-07054894 可用于炎症性肠病的研究。 |
T63340 |
CCG-273220
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CCG-273220 是 G 蛋白偶联受体 (GPCR) 激酶 5 (GRK5) 共价抑制剂 (IC50: 220 nM)。CCG-273220 可以共价结合GRK5亚家族特异性残基 Cys474 ,而对GRK5的选择性比 GRK2 高。 |
TMPY-04562 |
GRK2 Protein, Human, Recombinant (His & GST Tag)
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G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquito... |
T70468 |
MK-8666
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MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also... |
T69953 |
MK-8666 Tris
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MK-8666 is a partial GPCR (G-protein-coupled receptor) agonist that is coordinated with the action of GPR40. GPR40, also... |
TMPY-02837 |
GPR114 Protein, Human, Recombinant (hFc Tag)
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GPR114 belongs to the G-protein coupled receptor 2 family. Members of this family share a common molecular architecture ... |
T36578 |
Boc-Lys(Ac)-AMC
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Commendamide (N-acyl-3-hydroxypalmitoyl-glycine) is a newly discovered GPCR G2A/GPR132 agonist (EC50=11.8 μM) that isola... |
T36550 |
CAY10535
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TPα and TPβ are two isoforms of the human TP receptor, the G protein-coupled receptor (GPCR) that mediates the actions o... |
T36013 |
Lysophosphatidylcholines
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Lyso-Lecithins (egg) |
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Lysophosphatidylcholines are produced by hydrolysis of the fatty acid of phosphatidylcholine at either the sn-1 or sn-2 ... |