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Proton pump

A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane.During evolution, proton pumps have arisen independently on multiple occasions. Thus, not only throughout nature but also within single cells, different proton pumps that are evolutionarily unrelated can be found. Proton pumps are divided into different major classes of pumps that use different sources of energy, have different polypeptide compositions and evolutionary origins.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T78218 Ilaprazole sodium hydrate 2322264-11-7 98%
Ilaprazole sodium hydrate
Ilaprazole (IY-81149) sodium hydrate is an orally active proton pump inhibitor that irreversibly inhibits H+/K+-ATPase in rabbit parietal cells with a dose-depen...
T81119 S-Pantoprazole sodium trihydrate 1416988-58-3 98%
S-Pantoprazole sodium trihydrate
S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a pro...
T11816 Lansoprazole-d4 934294-22-1 98%
Lansoprazole-d4
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
T11817 Lansoprazole Sulfide D4 1216682-38-0 98%
Lansoprazole Sulfide D4
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC5...
T14051 5-Hydroxylansoprazole 131926-98-2 98%
5-Hydroxylansoprazole
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. Th...
T0674 Lansoprazole 103577-45-3 99.84%
Lansoprazole
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME...
T1734 Rabeprazole Sulfide 117977-21-6 99.80%
Rabeprazole Sulfide
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.
T29164 WY-47766 134217-27-9 99.75%
WY-47766
WY-47766 (OST-766) is a small molecule proton pump inhibitor that can be used to study postmenopausal osteoporosis.
T0502 Zinc pyrithione 13463-41-7 99.64%
Zinc pyrithione
Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.
T6928 Pantoprazole 102625-70-7 99.63%
Pantoprazole
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
T2686L Esomeprazole Sodium 161796-78-7 99.58%
Esomeprazole Sodium
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an ...
T22391 Omeprazole Sodium 95510-70-6 99.57%
Omeprazole Sodium
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibit...
T1651 Rabeprazole sodium 117976-90-6 99.36%
Rabeprazole sodium
Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Z...
T28665 Saviprazole 121617-11-6 99.20%
Saviprazole
Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.
T6929 Pantoprazole sodium 138786-67-1 99.1%
Pantoprazole sodium
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, w...
T1756L Ilaprazole 172152-36-2 99.08%
Ilaprazole
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also ...
T1756 Ilaprazole sodium 172152-50-0 99.06%
Ilaprazole sodium
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumul...
T1021 (R)-Lansoprazole 138530-94-6 98.96%
(R)-Lansoprazole
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activit...
T2188 Thonzonium Bromide 553-08-2 98.93%
Thonzonium Bromide
Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-depen...
T6740 Bafilomycin A1 88899-55-2 98.88%
Bafilomycin A1
Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of ...
Ilaprazole sodium hydrate
T78218
Ilaprazole (IY-81149) sodium hydrate is an orally active proton pump inhibitor that irreversibly inhibits H+/K+-ATPase in rabbit parietal cells with a dose-depen...
S-Pantoprazole sodium trihydrate
T81119
S-Pantoprazole (sodium trihydrate), a variant of Pantoprazole, is pivotal in managing diseases associated with gastric acid secretion disorders, serving as a pro...
Lansoprazole-d4
T11816
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
Lansoprazole Sulfide D4
T11817
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC5...
5-Hydroxylansoprazole
T14051
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. Th...
Lansoprazole
T0674
Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME...
Rabeprazole Sulfide
T1734
Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.
WY-47766
T29164
WY-47766 (OST-766) is a small molecule proton pump inhibitor that can be used to study postmenopausal osteoporosis.
Zinc pyrithione
T0502
Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.
Pantoprazole
T6928
Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disea...
Esomeprazole Sodium
T2686L
Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an ...
Omeprazole Sodium
T22391
Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibit...
Rabeprazole sodium
T1651
Rabeprazole sodium (Habeprazole Sodium) is a 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of stomach ulcers and Z...
Saviprazole
T28665
Saviprazole (Hoe-731), a proton pump inhibitor, is used potentially for treatment of gastric ulcer.
Pantoprazole sodium
T6929
Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, w...
Ilaprazole
T1756L
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also ...
Ilaprazole sodium
T1756
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumul...
(R)-Lansoprazole
T1021
(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activit...
Thonzonium Bromide
T2188
Thonzonium bromide is a mono-cationic surfactant that is structurally similar to Farnesol as an antimicrobial agent. It inhibits proton transport in a dose-depen...
Bafilomycin A1
T6740
Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of ...
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