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Proton pump

A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane.During evolution, proton pumps have arisen independently on multiple occasions. Thus, not only throughout nature but also within single cells, different proton pumps that are evolutionarily unrelated can be found. Proton pumps are divided into different major classes of pumps that use different sources of energy, have different polypeptide compositions and evolutionary origins.
Cat. No. Product name CAS No. Purity Chemical Structure
T5449 Bamaquimast 135779-82-7 98%
Bamaquimast is an inhibitor of proton pump
T14051 5-Hydroxylansoprazole 131926-98-2 98%
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatme...
T11817 Lansoprazole Sulfide D4 1216682-38-0 98%
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC5...
T11816 Lansoprazole-d4 934294-22-1 98%
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
T21254 Vonoprazan Fumarate 881681-01-2 98%
Vonoprazan Fumurate, a novel potassium-competitive acid blocker, inhibits gastric acid secretion by competitively inhibiting K+ binding sites on H+, K+ - ATPase
T16682 Pumaprazole 158364-59-1 98%
Pumaprazole is an antagonist of a reversible proton pump.
T6700 Tenatoprazole 113712-98-4 98%
Tenatoprazole, a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).
T8388 Vonoprazan 881681-00-1 98%
Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
T6740 Bafilomycin A1 88899-55-2 98%
Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Bafilomycin A1 is a vacuola...
T11191 EN6 1808714-73-9 98%
EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activati...
T16865 SCH28080 76081-98-6 98%
SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhib...
T0757 Omeprazole 73590-58-6 98%
Omeprazole is a proton pump inhibitor (PPI), Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
T40437L Caloxin 2A1 acetate 98%
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140...
T20626 Esomeprazole 119141-88-7 98%
Esomeprazole is the S-isomer of omeprazole, it is used in Gastro-oesophageal reflux disease (GORD).
T17030 Tegoprazan 942195-55-3 98%
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastr...
T0161 Pantoprazole Sodium Hydrate 164579-32-2 98%
Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease....
T21651 Lansoprazole sodium 226904-00-3 98%
Lansoprazole sodium is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and...
T6368 Abscisic Acid 21293-29-8 98%
Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and...
T10221 Abeprazan hydrochloride 1902954-87-3 98%
Abeprazan hydrochloride is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to pot...
T20714 Levolansoprazole 138530-95-7 98%
Levolansoprazole, a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 µM). It also inhibits acid formation ...
Bamaquimast
T5449
Bamaquimast is an inhibitor of proton pump
5-Hydroxylansoprazole
T14051
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatme...
Lansoprazole Sulfide D4
T11817
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC5...
Lansoprazole-d4
T11816
Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
Vonoprazan Fumarate
T21254
Vonoprazan Fumurate, a novel potassium-competitive acid blocker, inhibits gastric acid secretion by competitively inhibiting K+ binding sites on H+, K+ - ATPase
Pumaprazole
T16682
Pumaprazole is an antagonist of a reversible proton pump.
Tenatoprazole
T6700
Tenatoprazole, a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).
Vonoprazan
T8388
Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
Bafilomycin A1
T6740
Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Bafilomycin A1 is a vacuola...
EN6
T11191
EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activati...
SCH28080
T16865
SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhib...
Omeprazole
T0757
Omeprazole is a proton pump inhibitor (PPI), Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
Caloxin 2A1 acetate
T40437L
Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140...
Esomeprazole
T20626
Esomeprazole is the S-isomer of omeprazole, it is used in Gastro-oesophageal reflux disease (GORD).
Tegoprazan
T17030
Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastr...
Pantoprazole Sodium Hydrate
T0161
Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease....
Lansoprazole sodium
T21651
Lansoprazole sodium is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and...
Abscisic Acid
T6368
Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and...
Abeprazan hydrochloride
T10221
Abeprazan hydrochloride is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to pot...
Levolansoprazole
T20714
Levolansoprazole, a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 µM). It also inhibits acid formation ...
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