Proton pump

A proton pump is an integral membrane protein pump that builds up a proton gradient across a biological membrane.During evolution, proton pumps have arisen independently on multiple occasions. Thus, not only throughout nature but also within single cells, different proton pumps that are evolutionarily unrelated can be found. Proton pumps are divided into different major classes of pumps that use different sources of energy, have different polypeptide compositions and evolutionary origins.

Cat. No.	Product name	CAS No.	Purity
T5449	Bamaquimast	135779-82-7	98%
T5449	Bamaquimast is an inhibitor of proton pump
T14051	5-Hydroxylansoprazole	131926-98-2	98%
T14051	5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatme...
T11817	Lansoprazole Sulfide D4	1216682-38-0	98%
T11817	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC5...
T11816	Lansoprazole-d4	934294-22-1	98%
T11816	Lansoprazole D4 (AG-1749 D4) is a deuterium labeled Lansoprazole. Lansoprazole is an inhibitor of proton pump which prevents the stomach from producing acid.
T21254	Vonoprazan Fumarate	881681-01-2	98%
T21254	Vonoprazan Fumurate, a novel potassium-competitive acid blocker, inhibits gastric acid secretion by competitively inhibiting K+ binding sites on H+, K+ - ATPase
T16682	Pumaprazole	158364-59-1	98%
T16682	Pumaprazole is an antagonist of a reversible proton pump.
T6700	Tenatoprazole	113712-98-4	98%
T6700	Tenatoprazole, a prodrug of the proton pump inhibitor (PPI) class, can inhibit proton transport (IC50: 3.2 μM).
T8388	Vonoprazan	881681-00-1	98%
T8388	Vonoprazan is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis
T6740	Bafilomycin A1	88899-55-2	98%
T6740	Bafilomycin A1 induces caspase-independent cell death in hepatocellular carcinoma cells via targeting of autophagy and MAPK pathways. Bafilomycin A1 is a vacuola...
T11191	EN6	1808714-73-9	98%
T11191	EN6-mediated ATP6V1A modification decouples the v-ATPase from the Rags, leading to inhibition of mTORC1 signaling, increased lysosomal acidification and activati...
T16865	SCH28080	76081-98-6	98%
T16865	SCH28080 is a reversible and K+-competitive inhibitor of gastric H+/K+-ATPase with an IC50 value of 20 nM (rabbit microsomal membrane).SCH28080 is a potent inhib...
T0757	Omeprazole	73590-58-6	98%
T0757	Omeprazole is a proton pump inhibitor (PPI), Omeprazole is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).
T40437L	Caloxin 2A1 acetate		98%
T40437L	Caloxin 2A1 acetate is an inhibitor of extracellular plasma membrane Ca2+-ATPase (PMCA) peptide. Caloxin 2A1 acetate inhibits Ca2+-dependent formation of the 140...
T20626	Esomeprazole	119141-88-7	98%
T20626	Esomeprazole is the S-isomer of omeprazole, it is used in Gastro-oesophageal reflux disease (GORD).
T17030	Tegoprazan	942195-55-3	98%
T17030	Tegoprazan is a potassium-competitive acid blocker and is a potent, oral active, and highly selective inhibitor of gastric H+/K+-ATPase. That could control gastr...
T0161	Pantoprazole Sodium Hydrate	164579-32-2	98%
T0161	Pantoprazole is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease....
T21651	Lansoprazole sodium	226904-00-3	98%
T21651	Lansoprazole sodium is a proton pump inhibitor (PPI) and a potent inhibitor of gastric acidity which is widely used in the therapy of gastroesophageal reflux and...
T6368	Abscisic Acid	21293-29-8	98%
T6368	Abscisic Acid is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and...
T10221	Abeprazan hydrochloride	1902954-87-3	98%
T10221	Abeprazan hydrochloride is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to pot...
T20714	Levolansoprazole	138530-95-7	98%
T20714	Levolansoprazole, a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 µM). It also inhibits acid formation ...