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Cell Cycle/Checkpoint IRE1

IRE1

Cat No. product name
T15594 MKC8866 MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased produc...
TQ0101 MKC3946 MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.
T7483 6-Bromo-2-hydroxy-3-methoxybenzaldehyde 6-Bromo-2-hydroxy-3-methoxybenzaldehyde is an inhibitor of IRE-1α (IC50 : 0.08 μM).
T6681 STF083010 STF-083010 is a selective inhibitor of the IRE1α endonuclease.
T6363 4μ8C 4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.
T3654 APY29 APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.
MKC8866
T15594CAS 1338934-59-0
MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29 μM in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased produc...
MKC3946
TQ0101CAS 1093119-54-0
MKC3946 is an effective and soluble IRE1α inhibitor which triggered modest growth inhibition in multiple myeloma cell lines.
6-Bromo-2-hydroxy-3-methoxybenzaldehyde
T7483CAS 20035-41-0
6-Bromo-2-hydroxy-3-methoxybenzaldehyde is an inhibitor of IRE-1α (IC50 : 0.08 μM).
STF083010
T6681CAS 307543-71-1
STF-083010 is a selective inhibitor of the IRE1α endonuclease.
4μ8C
T6363CAS 14003-96-4
4μ8C(IC50=76 nM) is an effective and specific IRE1 Rnase inhibitor.
APY29
T3654CAS 1216665-49-4
APY29 is an allosteric modulator of IRE1α; inhibits IRE1α autophosphorylation (IC50 = 280 nM) and activates IRE1α RNase activity.