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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T20793 | Magnesium Lithospermate B | Monomethyl lithospermate B,Lithospermate B | Others |
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is... | |||
T61098 | RUNX1/ETO tetramerization-IN-1 | ||
RUNX1/ETO tetramerization-IN-1 is a small-molecule inhibitor that specifically targets NHR2 of RUNX1/ETO, effectively inhibiting the tetramerization process. With an EC50 value of 0.25 μM, this compound successfully rest... | |||
T9108 | BI-0115 | Lipoxygenase | |
BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX... | |||
T68986 | ZINC08383544 | ||
ZINC08383544 is a specific pyruvate kinase M2 activator which promotes the formation of PKM2 tetramer. ZINC08383544 effectively blocks PKM2 nuclear translocation, and inhibits the growth of tumor. | |||
T40132 | Insulin β Chain Peptide (15-23) | ||
Insulin β Chain Peptide (15-23), also referred to as INS, is an insulin-derived peptide that is specifically recognized by islet-associated T cells. The tetramer of Insulin β Chain Peptide (15-23) effectively stained the... | |||
T71785 | GUN35758 | ||
GUN35758, also known as 4'-Carboxybenzo-18C6, is a novel transthyretin (ttr) amyloidogenesis inhibitor, stabilizing the ttr tetramer by binding to the allosteric sites on the molecular surface of the ttr tetramer. Thi... | |||
T21318 | Efaproxiral | RSR13,Efaproxyn,RSR 13,RSR-13 | |
Efaproxiral is a synthetic small molecule with radiosensitizing activity. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen... | |||
T79286 | TRAP1-IN-2 | HSP | |
TRAP1-IN-2, also known as compound 36, is a selective degrader of the TRAP1 client protein that does not affect Hsp90-cytosolic clients. It inhibits oxidative phosphorylation (OXPHOS) and shifts cellular metabolism towar... |