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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4022 | QS11 | QS 11 | GTPase |
QS11 is a GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) inhibitor. Modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation. Also r... | |||
TQ0211 | Brusatol | (+)-Brusatol,NSC 172924 | Others , Ferroptosis , Nrf2 |
Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2. | |||
T27405 | GAT211 | GAT-211,AZ-4,GAT 211,AZ 4,AZ4 | |
GAT211 is a CB1 positive allosteric modulator. GAT211 suppresses allodynia and produces synergistic antiallodynic effects with monoacylglycerol lipase and fatty acid amide hydrolase inhibitors in paclitaxel-treated mice. | |||
T4763 | Trans-Cyclohexane-1,2-diol | trans-1,2-Cyclohexanediol | Others , Endogenous Metabolite |
trans-Cyclohexane-1,2-diol (trans-1,2-Cyclohexanediol) has a synergistic retardation effect on percutaneous absorption and penetration of metronidazole (MTZ). | |||
T36404L | PRLX-93936 HCL | PRLX-93936 hcl(903499-49-0 Free base) | Ferroptosis , Reactive Oxygen Species |
PRLX-93936 HCL is an analog of erastin and demonstrated synergistic effects against non-small cell lung cancer (NSCLC) cells with cisplatin. | |||
TN1113 | Vincetoxicoside B | Anti-infection , Antifungal | |
Vincetoxicoside B, isolated from Polygonum paleaceum Wall. Vincetoxicoside B , quercetin, kaempferol , and (-)-epicatechin show synergistic antifungal activities with the FICI values <0.5. | |||
T26168 | Rufigallol | AI3 00865,AI3-00865,AI300865 | |
Rufigallol (AI3-00865) is an electron-deficient disk-shaped molecule with six hydroxyl groups and is a good unit for inducing the formation of DLC from non-planar AIE molecules, an anthraquinone derivative.Rufigallol ind... | |||
T9498 | BAY-8400 | DNA-PK | |
BAY-8400 is an orally active, potent and selective DNA-dependent protein kinase ( DNA-PK ) inhibitor ( IC 50 =81 nM) which shows synergistic efficacy in combination with targeted alpha therapies. BAY-8400 can be used for... | |||
T11096 | DRI-C21045 | NF-κB | |
Dri-c21045 showed concentration-dependent inhibition of NF- B activation and all CD40L induced by B cell proliferation. IC50 was 17.1 M and 4.5 M, respectively.Dri-c21045 is an effective selective inhibitor of CD40-CD40L... | |||
T60446 | LCS3 | Apoptosis , Glutathione reductase | |
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in... | |||
T77495 | WDR5-IN-6 | JAK | |
WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6 exhibits potent antitumor activity and inhibits cell proliferati... | |||
TN3700 | Corianin | Others | |
Corianin and coriatin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm. | |||
T70373 | AS2575959 | ||
AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion. | |||
TN3701 | Coriatin | Others | |
Coriatin and corianin demonstrate synergistic effect to insecticidal activity of tutin againstarmyworm. | |||
TN2094 | Polyphyllin E | Others | |
Polyphyllin E has synergistic anticancer effects. | |||
T23633 | Adechlorin | ||
Adechlorin is a synergistic antitumor and/or antiviral antibiotic. It potentiates the effects of other antitumor or antiviral compounds through the inhibition of key enzymes. | |||
TN2524 | 1-Acetyl-β-carboline | 1-Acetyl-beta-carboline | Antifection |
Combination of 1-acetyl-beta-carboline with ampicillin exhibits synergistic antibacterial activity against MRSA. | |||
T27052 | CMP3a | CMP-3a,CMP 3a | |
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse model and exhibited a synergistic effect with radiotherapy. Targeting NEK2 attenuates glioblastoma growth and radioresistance by destab... | |||
T30831 | Cgp 43182 | Cgp-43182,Cgp43182 | |
CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines media... | |||
TN1518 | Cochinchinenin C | Others | |
There is a synergistic interaction between loureirin A and Cochinchinenin C, and the fluorescence quenching of HSA by loureirin A (or Cochinchinenin C) is a combined quenching procedure (dynamic and static quenching). |