ovary — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T6609	NMS-E973		HSP
	NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.		HSP
T22641	CDPPB		GluR
	CDPPB is a modulator of mGluR5 positive allosteric(with an EC50 of 27 nM in Chinese hamster ovary cells expressing human mGluR5).		GluR
T6788	Bitopertin	Paliflutine,RO4917838,RG1678	GlyT
	Bitopertin (Paliflutine) (RG1678, RO-4917838) is a potent inhibitor of glycine transporter 1 (GlyT1), with Ki of 8.1 nM for human hGlyT1b and IC50 of 22-25 nM in Chinese hamster ovary cells.		GlyT
T9916	Alirocumab		Others
	Alirocumab is a human monoclonal antibody that inhibits PCSK9. It is produced by recombinant DNA technology in Chinese hamster ovary cell suspension culture.		Others
T12970	Solabegron	GW 427353	Adrenergic Receptor
	Solabegron (GW 427353) is a selective agonist of β3-adrenergic receptor, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR(EC50 : 22 nM). It is used for treatment of overactive bladd...		Adrenergic Receptor
T50086	Clomesone		Others
	Clomesone is a synthetic non-steroidal drug that can be used as a molecular structural unit. It is a drug commonly used to treat female infertility and works by blocking the action of estrogen in the brain. It has been s...		Others
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
T23549	YM 511		P450 , Aromatase
	YM 511 is a highly specific non-steroidal aromatase inhibitor. YM 511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM 511 slightly ...		P450 , Aromatase
TP1425	Motilin (26-47), human, porcine		Motilin Receptor
	Motilin (26-47), human and pig are endogenous Motilin receptor ligands in Chinese hamster ovarian cell lines, with Ki and EC50 at 2.3 nM and 0.3 nM, respectively.		Motilin Receptor
T33411	Mitopodozide	SP-I 77,SPI 77,SPI-77
	Mitopodozide, as an ethylhydrazide derivative of podophyllic acid, acts as a mitotic poison in carcinomas of the ovary.
T80602	Dovanvetmab	ZTS-00521505
	Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO) cells [1].
T82507	Ecleralimab	CSJ-117,NVP-CSJ117
	Ecleralimab (CSJ-117; NVP-CSJ117), a Fab-IgG1-λ2 monoclonal antibody, selectively targets thymic stromal lymphopoietin (TSLP). It is typically produced using a Chinese Hamster Ovary (CHO) cell expression system [1].
T71904	Chlormadinone (free base)
	Chlormadinone (free base) is a synthetic steroid hormone and antagonist at androgen and estrogen receptors used to treat BPH and polycystic ovary syndrome. It also promotes osteoblast differentiation and Ca deposition in...
T82511	Ebdarokimab
	Ebdarokimab (AK101), a humanized IgG1-κ antibody, is typically produced in Chinese Hamster Ovary (CHO) cells [1].
T80603	Dresbuxelimab	AK-119	CD73
	Dresbuxelimab (AK-119), an IgG-κ monoclonal antibody, selectively targets CD73 and is commonly produced using a Chinese Hamster Ovary (CHO) cell expression system [1].		CD73
T80611	Sasanlimab	PF-06801591	PD-1/PD-L1
	Sasanlimab (PF-06801591), a humanized IgG4-κ antibody, selectively targets PD-1 and is primarily produced in Chinese Hamster Ovary (CHO) cells [1].		PD-1/PD-L1
T80596	Coprelotamab	GB-221	EGFR
	Coprelotamab (GB-221) is an IgG-κ monoclonal antibody that targets EGFR2, frequently produced in CHO DG44 (Chinese Hamster Ovary) cells [1].		EGFR
T80608	Ebronucimab	AK102
	Ebronucimab (AK102), an IgG1-λ2 antibody, specifically targets PCSK9 and is predominantly produced in CHO DG44 (Chinese Hamster Ovary) cells [1].
T64298	Turoctocog alfa
	Turoctocog alfa is a recombinant coagulation factor VIII (FVIII) derived from Chinese hamster ovary (CHO) cells. turoctocog alfa can be used in the study of haemophilia A.
T80614	Serclutamab	DC-1630423,PR-1594407	EGFR
	Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR). It is primarily produced in Chinese Hamster Ovary (CHO) cells [1].		EGFR