monitor

TCN 213 is an antagonist of NMDA receptor that has a selective for NR1/NR2A over NR1/NR2B

5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine used to monitor de novo DNA synthesis through click chemistry and serves as an alkyl chain-based PROTAC linker for synthesizing PROTACs.

The bentiromide test is an excellent means of confirming the diagnosis of pancreatic exocrine insufficiency by outpatient test of chymotrypsin function[1]. Bentiromide is a peptide which is broken down in the pancreas by chymotrypsin.

Bentiromide acetate is a peptide used as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy. It is broken down by the pancreatic enzyme chymotrypsin, yielding p-aminobenzoic acid (PABA).

Ethyl L-leucinate HCl has been used as a hypertrophic agent to monitor its effects on myotubes and has also been used as a component of PMG media for culturing yeast.

HBT-O is a fluorescent probe used to monitor subtle pH fluctuations in living cells.

NIR-O2˙– is a NIR NIR O2˙– probe which displays superior sensitivity to NIR O2˙– and has the capability to monitor trace amounts of intracellular NIR O2˙– in AKI in vivo.

4-carboxy TEMPO is a nitroxide and spin label. Nitroxides such as 4-carboxy TEMPO react with reactive oxygen species (ROS) and can be used with electron spin resonance (ESR) spectroscopy to monitor ROS production in vivo., It has also been used to study flavin-photosensitized damage in inner mitochondrial membranes.

Pal-KTTKS is a lipidated pentapeptide consisting of a fragment of the type I collagen C-terminal propeptide conjugated to palmitic acid .1 It increases collagen production in human corneal and dermal fibroblasts when used at concentrations of 0.002, 0.004, and 0.008 wt%.2 Following topical administration, pal-KTTKS (50 μg/cm2) is found in the stratum corneum, epidermis, and dermis of isolated hairless mouse skin.1 It can self-assemble into flat tapes and extended fibrillar structures.3 Pal-KTTKS has been detected in anti-wrinkle creams.4 |1. Choi, Y.L., Park, E.J., Kim, E., et al. Dermal stability and in vitro skin permeation of collagen pentapeptides (KTTKS and palmitoyl-KTTKS). Biomol. Ther. (Seoul) 22(4), 321-327 (2014).|2. Jones, R.R., Castelletto, V., Connon, C.J., et al. Collagen stimulating effect of peptide amphiphile C16-KTTKS on human fibroblasts. Mol. Pharm. 10(3), 1063-1069 (2013).|3. Castelletto, V., Hamley, I.W., Whitehouse, C., et al. Self-assembly of palmitoyl lipopeptides used in skin care products. Langmuir 29(29), 9149-9155 (2013).|4. Chirita, R.-I., Chaimbbault, P., Archambault, J.-C., et al. Development of a LC-MS/MS method to monitor palmitoyl peptides content in anti-wrinkle cosmetics. Anal. Chim. Acta 641(1-2), 95-100 (2009).

MXS is a mitochondria-targeted fluorescent probe for hypochlorous acid (HOCl).1It selectively fluoresces in the presence of OCl-over O2, H2O2, NO, NO2-, NO3-, O2-, ONOO-, and OH when used at a concentration of 10 μM. MXS has been used to monitor real-time mitochondrial HOCl levels in living cells. It displays excitation/emission maxima of 530/654 nm, respectively.

Ethyl 4-methyloctanoate (Oryctalure) is an aggregation pheromone produced by beetles, which can be used by beetles to find suitable feeding sites. Ethyl 4-methyloctanoate can be used to monitor and trap coconut rhinoceros beetles (CRB).

2-undecyloxy-ethanol is a monophyllous pheromone that can be used to monitor and control the population of pine saw-toothed beetles.

PLLA5000-PEG5000-RhB is a polylactic acid derivative with a terminal rhodamine label. It is useful for labeling nanomicelles to monitor drug release in vivo in real time.

PLLA5000-PEG2000-RhB is a terminal rhodamine-labeled polylactic acid derivative. It is used for labeling nanomicelles to monitor drug release in vivo in real-time.

PLLA4000-PEG3000-RhB is a polylactic acid derivative with terminal rhodamine labeling. It can be utilized for tagging nanomicelles to monitor drug release in vivo in real-time.

PLLA3000-PEG2000-RhB is a polylactic acid derivative with terminal rhodamine labeling. This compound can be utilized for tagging nanomicelles to monitor drug release in vivo in real time.

trans-4-(Trifluoromethyl)cinnamic acid is a photosensitizing compound. It is used as a reagent in the synthesis of various compounds, such as heterocyclic compounds and pharmaceuticals. It has also been used as a catalyst for organic reactions such as the Heck reaction and the Suzuki-Miyaura reaction. It is also used as a fluorescent probe in biological studies to detect and monitor various biomolecules.

(Z-IETD)2-Rh 110 is a fluorescent substrate for caspase-8 (λex= 488 nm, λem= 523 nm) and can be used to measure caspase-8 activity and monitor apoptosis.

Iodocholine iodide is a non-toxic, metabolizable green catalyst capable of catalyzing the radical polymerization of functional polymers. It also serves as the non-radioactive iodide form of Carbon-11 choline. C-11 choline is employed in PET imaging and non-informative bone scintigraphy, CT, or MRI to monitor various types of cancer.