lymphomas — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T7318	Elimusertib	BAY-1895344	ATM/ATR
	Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy in monotherapy and strong combination potential with the target...		ATM/ATR
T0707L	Cyclophosphamide		DNA Alkylator/Crosslinker , DNA , MRP
	Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer.		DNA Alkylator/Crosslinker , DNA , MRP
T16702	QL47		Virus Protease , BTK
	QL47 is a host-targeted small molecule antiviral agent with antiviral activity against dengue and other RNA viruses.QL47 acts as an inhibitor of viral translation and a covalent inhibitor of BTK, and can be used in the s...		Virus Protease , BTK
T8380	Bendamustine	SDX105	Apoptosis , Others , DNA Alkylator/Crosslinker
	Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia		Apoptosis , Others , DNA Alkylator/Crosslinker
T76707	Brentuximab vedotin	SGN-35	Others
	Brentuximab vedotin (SGN-35) is an antibody-activated molecule coupling (ADC) targeting CD30 with antitumor activity for the study of lymphomas.		Others
T76685	Glofitamab	RO7082859,RG 6026,CD20-TCB	Others
	Glofitamab (RO7082859) is a novel bivalent antibody directed against CD20-binding T cells.Glofitamab promotes T cell proliferation and activation and tumor cell killing by binding to CD20 on malignant cells.Glofitamab ca...		Others
T70388	(S)-Enitociclib	VIP152	CDK
	(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that induces complete regression of MYC+ lymphomas by inhibiting RNA polymerase II-mediated transcription of anti-apoptotic and pro-survival proteins.		CDK
T73140	MAT2A-IN-9		Methionine Adenosyltransferase (MAT)
	MAT2A-IN-9, a 2-oxoquinazoline derivative, is a potent MAT2A (methionine adenylyltransferase 2A) inhibitor.MAT2A-IN-9 has antitumor activity for the treatment of lymphomas and solid tumors.		Methionine Adenosyltransferase (MAT)
T26754	BC-23	NSC 45382,BC 23,BC23,NSC-45382,NSC45382	Proteasome
	BC-23 (NSC 45382) is a potent proteasome inhibitor with antitumor and antimicrobial activity.BC-23 inhibits the CT-L activity of the proteasome and is used in the study of leukemias, lymphomas, gliomas, breast cancer, an...		Proteasome
T73400L	PG-11047 2HCl	PG-11047 2HCl(949933-50-0 Free base),CGC-11047 2HCl	Apoptosis
	PG-11047 2HCl is an apoptosis-stimulating agent used in the treatment of genitourinary disorders, immune system disorders, genetic disorders and malformations, ocular disorders, and disorders of the blood and lymphatic s...		Apoptosis
T70563	KC-11404
	KC-11404 is an LTB4 inhibitor for the treatment of b-cell leukemias and lymphomas, potently inhibiting histamine, platelet activating factor and 5-lipoxygenase.
T24548	NSC10010 hydrochloride	NSC#10010,NSC 10010,NSC# 10010,NSC#-10010,NSC-10010
	NSC10010 hydrochloride is an effective growth inhibitor for gammaherpesvirus-associated B-lymphomas. It acts through activation of both the NF-κB and c-Myc-mediated signaling pathways.
T74096	Prednimustine
	Prednimustine (Leo 1031;NSC 134087) is the ester formed from Prednisolone and Chlorambucil . Prednimustine can be used for leukemias and lymphomas research [1] .
T77008	Finotonlimab
	Finotonlimab (SCT-I10A), a humanized IgG PD-1 monoclonal antibody, shows potential in the research of solid tumors or lymphomas [1].
T23872	Cellocidin	NSC65381,NSC# 65381,NSC-65381,NSC#65381,NSC 65381
	Cellocidin is a potent gammaherpesvirus-associated B-lymphomas growth inhibitor. It acts through the activation of both the NF-κB and c-Myc-mediated signaling pathways.
T70759	CUDC-907 mesylate
	CUDC-907 mesylate is a small molecule inhibitor of histone deacetylase and PI3 kinase developed by Curis. It is investigated in clinical trials for the treatment of relapsed or refractory lymphomas, thyroid cancer, multi...
T61084	Tubulin polymerization-IN-37
	Tubulin polymerization-IN-37 is a potent inhibitor (IC50: 2.3 μΜ) of tubulin polymerization by binding specifically to the colchicine site of tubulin and preventing colchicine binding. It has potential applications in ca...
T16131	MPT0E028		Others
	MPT0E028 is an orally active and selective inhibitor of HDAC (IC50s of 53.0 nM, 106.2 nM, 29.5 nM for HDAC1, HDAC2, and HDAC6, respectively). MPT0E028 has good anticancer activity. MPT0E028 decreases the viability of B-c...		Others
T76805	Epratuzumab
	Epratuzumab (Antibody hLL 2), an anti-CD22 IgG1 monoclonal antibody, serves as both a tumor-imaging and immunomodulatory agent. It induces CD22 phosphorylation and has been employed in researching Non-Hodgkin’s Lymphomas...
T77823	Polatuzumab vedotin
	Polatuzumab vedotin, an antibody-drug conjugate, selectively targets CD79b with a humanized anti-CD79b IgG1 monoclonal antibody bound to monomethyl auristatin E (MMAE), a robust microtubule inhibitor. This compound shows...