inosine

Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Inosine has anti-inflammatory, immunomodulatory, antinociceptive and neuroprotective effects.

Inosine-5'-triphosphate (ITP) lithium salt is a nucleotide analog that targets various G proteins. It interacts with the α subunit of G proteins, serving as a substitute for GTP in G protein-mediated signal transduction. By binding to the nucleotide site on the G protein α subunit, it influences the activity and function of G proteins. This compound is utilized to study the roles of G proteins in cellular physiology and pathological processes.

Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects and others, isoprinosine shows antiviral activity and has applications against subacute sclerosing panencephalitis. It also restores depressed immune responses in Y patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy. It is most commonly used to treat the rare measles complication subacute sclerosing panencephalitis in conjunction with intrathecal interferon therapy.

Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis.

1-Methylinosine (N1-Methylinosine) is a modified nucleotide found at position 37 in tRNA 3' to the anticodon of eukaryotic tRNA and has a role as a metabolite.

Inosine-5'-triphosphate trisodium salt (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine-5'-triphosphate trisodium salt (ITP) may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. Inosine-5'-triphosphate trisodium salt (ITP) is also used to study activation of various ATPases and GTPases.

2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally active purine nucleoside analog with antihypertensive activity.

Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in research on cutaneous T-cell lymphoma, psoriasis and HIV infection.

Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.

6-Hydroxyadenosine (inosine oxime) is an endogenous metabolite that inhibits the growth and proliferation of HeLa and K562 cells and is further metabolised into inosine in HEK293 cells.

Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor designed to concentrate within the liver to target HCV-infected hepatocytes, while minimizing distribution within red blood cells and the development of hemolytic anemia [2].

Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffective in modifying the virologic or clinical course of experimental influenza A (H1N1) virus infection.

Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the deamination of AMP and when hydrolysed produces inosine. Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

INOSINIC ACID (Standard) is the standard substance of INOSINIC ACID, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the deamination of AMP and when hydrolysed produces inosine. Inosinic acid is the ribonucleotide of hypoxanthine and is the first compound formed during the synthesis of purine.Inosine 5′-monophosphate (IMP) is used as a substrate to study the distribution, specificity and kinetics of inosine-5′-monophosphate dehydrogenase (IMPDH).

6-Methylmercaptopurine riboside is a purine nucleoside analogue applicable to biochemical experiments and drug synthesis studies.

8-Bromo TNP-ITP (8-Bromo TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt.

2-Chloro TNP-ITP (2-Chloro TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt.

Inosine 5'-diphosphate sodium, a purine ribonucleoside diphosphate with inosine as its nucleobase, plays a role in intracellular energy metabolism and signal transduction processes.

Inosine-5'-monophosphate Disodium Salt heptahydrate is a useful organic compound for research related to life sciences. The catalog number is T67245 and the CAS number is 849725-39-9.

L-Inosine, the L-configuration of Inosine, is an endogenous purine nucleoside derived from adenosine catabolism. It exhibits anti-inflammatory, antinociceptive (pain-relieving), immunomodulatory (immune system-modulating), and neuroprotective effects [1] [2].

8-Chloro-2'-O-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies, with anticancer mechanisms including DNA synthesis inhibition and apoptosis induction, among others [1].

N1-Methyl-2'-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies by inhibiting DNA synthesis and inducing apoptosis, among other mechanisms [1].

3'-O-(2-Methoxyethyl)inosine is a purine nucleoside analog known for its broad antitumor activity, particularly against indolent lymphoid malignancies. Its anticancer mechanisms include inhibition of DNA synthesis and the induction of apoptosis, among others [1].

3'-Deoxy-N1-Methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies. Its anticancer mechanisms involve the inhibition of DNA synthesis and induction of apoptosis, among other processes [1].