growth-regulated a protein

Expression system: E. coli
Length: 35-107, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 25-96, Full Length of Mature Protein
Activity: Cell Activity

Expression system: HEK293 Cells
Length: 20-96, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-467, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 19-247 (mutation), Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-425, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 31-678, Full Length of Mature Protein
Activity: BLI、ELISA

Expression system: HEK293 Cells
Length: 26-520, Partial
Activity: Not Tested

Vasorin is a Type I membrane protein, which is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. The expression level of Vasorin can be down regulated during vessel repair after arterial injury. Vasorin binds to transforming growth factor beta (TGF-β) and attenuates TGF-β signaling in vitro.

Expression system: E. coli
Length: 1-159, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 67­202, Partial
Activity: Not Tested

Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way suggesting that delivery of BMPs into the tissue is potentiated during apoptosis. Gain-of-function experiments demonstrated that BMP-5 has the same effect as other interdigital BMPs inducing apoptosis in the undifferentiated mesoderm and growth in the prechondrogenic mesenchyme. BMP-5 is a member of the 60A subgroup of BMPs, other members of which have been shown to stimulate dendritic growth in central and peripheral neurons. The signaling pathway that mediates the dendrite-promoting activity of BMP-5 may involve binding to BMPR-IA and activation of Smad-1, and relative levels of BMP antagonists such as noggin and follistatin may modulate BMP-5 signaling. Since BMP-5 is expressed at relatively high levels not only in the developing but also the adult nervous system, these findings suggest the possibility that BMP-5 regulates dendritic morphology not only in the developing but also the adult nervous system. BMP-5 may play important roles not only in myocardial differentiation but also in the formation and maintenance of endocardial cushion tissue. Additionally, a high expression level of BMP-5 has been detected in certain tumors of mesenchymal origin.

Expression system: HEK293 Cells
Length: 1-757, Full Length
Activity: Cells Activity

Expression system: HEK293 Cells
Length: 1-367, Full Length
Activity: Not Tested

CNTNAP2 CASPR2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5 8 type C domain, discoidin neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. CNTNAP2 CASPR2 is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This protein encoding gene is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation. CNTNAP2 CASPR2 may play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. CNTNAP2 CASPR2 Seems to demarcate the juxtaparanodal region of the axo-glial junction.

Expression system: HEK293 Cells
Length: 1-614, Full Length
Activity: Enzyme Activity

Expression system: E. coli
Length: 2-253, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 2-206, Full Length of Mature Protein
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-115, Partial
Activity: Not Tested

Expression system: E. coli
Length: 997-1337, Partial
Activity: Not Tested

Expression system: E. coli
Length: 14-420, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2-394, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-575, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-159, Full Length
Activity: Not Tested