glucuronide

Cholesterol glucuronide is an endogenous lipid metabolite generated by UDP-gluconyltransferase in the liver.

DiosMetin 7-O-β-D-Glucuronide, an antioxidant constituent found in the fruits of Luffa cylindrical, supplies antioxidant benefits when sponge gourds are consumed.

Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil, is a potent and competitive inhibitor of P450 (CYP) isoform CYP2C8, with an IC50 of 4.07 μM.

Ifenprodil glucuronide, a derivative of Ifenprodil, is a vasodilator and an inhibitor of platelet aggregation. In contrast to Ifenprodil, Ifenprodil glucuronide does not affect platelet aggregation nor arterial contraction.

Levothyroxine acyl glucuronide (Thyroxine Acyl-β-D-glucuronide) is the acyl glucuronide conjugate of thyroxine (T4), an endogenous metabolite.

Raloxifene 4'-glucuronide, a primary metabolite of Raloxifene.

Raloxifene 6,4'-Bis-β-D-glucuronide, a metabolite of Raloxifene, acts as a selective antagonist of the estrogen receptor used for osteoporosis prevention.

Raloxifene 6-glucuronide, a primary metabolite of Raloxifene, is mediated predominantly by UGT1A1 and UGT1A8.

T3 Acyl glucuronide is the acyl glucuronide formation of triiodothyronine (T3). T3 Acyl glucuronide is an endogenous metabolite

Wogonin 7-O-beta-D-glucuronide methyl ester, a natural product, is isolated from [Huanglian Jiedutang].

MAC glucuronide linker-1 is an ADC linker that can be used in the construction of antibody-coupled reactive molecules (ADCs) with the advantage of being cleavable.

MAC glucuronide linker-2 is an ADC linker employed in the synthesis of ADCs, offering cleavability [1].

MAC glucuronide phenol-linked SN-38, a pH-sensitive lactone and DNA topoisomerase I inhibitor drug linker, exhibits cytotoxicity in L540cy and Ramos cells, with IC50 values of 113 ng/mL and 67 ng/mL, respectively[1].

MAC glucuronide α-hydroxy lactone-linked SN-38 (Topoisomerase I inhibitor) is a cytotoxic drug linker that maintains a stabilized lactone form, demonstrating efficacy against L540cy and Ramos cells with IC50 values of 99 and 105 ng/mL, respectively[1].

Tricin 7-O-glucuronide is a flavonoid from Alfalfa (Medicago sativa L.).

Fenretinide glucuronide is a metabolite formed through the glucuronidation of Fenretinide. This process enhances the water solubility of Fenretinide and facilitates its excretion. Fenretinide glucuronide shows potential for research in the field of cancer.

Cholic acid 3-O-glucuronide (OCA-3-glucuronide) disodium acts as an agonist for the farnesoid X receptor (FXR) with an EC50 of 91.5 μM. It holds potential for research in bile acid metabolism and detoxification.

Posaconazole D-glucuronide (SCH 56592 D-glucuronide) is the glucuronide metabolite of the antifungal agent Posaconazole. It is formed in human liver microsomes through catalysis by UGT1A4.

Diclofenac Acyl Glucuronide (Diclofenac glucuronide) is an intestinal metabolite that accelerates intestinal ulcers.

Trifluoperazine N-Glucuronide is a metabolite of Trifluoperazine with antidepressant and antipsychotic activity.

Menthol glucuronide is a metabolite of L-(-)-Menthol, the natural form of Methanol.

Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.

Resveratrol-4'-O-D-Glucuronide has anti-fat accumulation properties, is metabolized by resveratrol, and can be used in metabolism-related studies.

Estradiol 3-sulfate 17β-Glucuronide potassium salt (Estradiol 3-sulfate 17-glucuronide potassium) is a naturally occurring estrogen that competitively inhibits MRP-mediated LTC transporter and can be used to study metabolic diseases.