Search Result

Search Results for " exosome "

Targets

Compounds

Natural Products

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T60043	DPTIP		Phospholipase
	DPTIP is an effective inhibitor of neutral sphingomyelinase 2 with an IC50 value of 30 nM.		Phospholipase
T4985	Neticonazole Hydrochloride		Antifungal
	Neticonazole Hydrochloride is an imidazole antifungal for the treatment of fungal skin infections. Neticonazole is reported as a potent exosome inhibitor which can block the activity of exosomes.		Antifungal
T1403	Climbazole	BAY-e 6975	Antibiotic , Antifungal
	Climbazole (BAY-e 6975) is a broad-spectrum imidazole antifungal agent with anti-dandruff benefits.		Antibiotic , Antifungal
T0674	Lansoprazole	A-65006,AG-1749	Proton pump , Phospholipase , Antibacterial
	Lansoprazole (A-65006) is a 2, 2, 2-trifluoroethoxypyridyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is fo...		Proton pump , Phospholipase , Antibacterial
T2017	U-104	NSC-213841,MST-104	Carbonic Anhydrase
	U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).		Carbonic Anhydrase
T6928	Pantoprazole	SKF96022,BY1023	Apoptosis , Proton pump , Autophagy
	Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Proton pump , Autophagy
T0161	Pantoprazole Sodium Hydrate	SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)	Apoptosis , Potassium Channel , Proton pump , Autophagy
	Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.		Apoptosis , Potassium Channel , Proton pump , Autophagy
T6929	Pantoprazole sodium	Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc	Apoptosis , Others , Proton pump , HIF , Autophagy
	Pantoprazole sodium (Pantecta) is the sodium salt form of a substituted benzimidazole with proton pump inhibitor activity. Pantoprazole sodium is a lipophilic, weak base that crosses the parietal cell membrane and enters...		Apoptosis , Others , Proton pump , HIF , Autophagy
T2686L	Esomeprazole Sodium	(S)-Omeprazole sodium	ATPase , Proton pump
	Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Esomeprazole acts as an exosome inhibitor by blocking the exosome release via the i...		ATPase , Proton pump
T2686	Esomeprazole Magnesium	(S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium	ATPase , Proton pump
	Esomeprazole Magnesium (NEXIUM) is the S-isomer of omeprazole, can reduce gastric acid secretion with selective and irreversible proton pump inhibitor activity.Esomeprazole magnesium acts as an exosome inhibitor by block...		ATPase , Proton pump
T3640	GW4869	GW554869A,GW 4869,GW69A	Phospholipase
	GW4869 (GW69A) is a selective and non-competitive inhibitor of neutral sphingomyelinase N-SMase (IC50=1 μM). GW4869 also inhibits exosome synthesis/release and is commonly used in exosome-related studies.		Phospholipase
T0750	Sulfisoxazole	NU-445,Sulfafurazole	Endothelin Receptor , Antibacterial , Antibiotic , Autophagy
	Sulfisoxazole (Sulfafurazole) is a short-acting sulfonamide antibacterial with activity against a wide range of gram-negative and gram-positive organisms.Sulfisoxazole inhibits breast cancer exosome release by targeting ...
T69757	PDDC inhibitor
	PDDC is the first nSMase2 inhibitor that possesses both favorable pharmacodynamics and pharmacokinetic (PK) parameters, including substantial oral bioavailability, brain penetration, and significant inhibition of exosome...
T0757	Omeprazole	Losec,Prilosec,H 16868,Antra	Proton pump , Phospholipase , Antibacterial , Autophagy
	Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor).		Proton pump , Phospholipase , Antibacterial , Autophagy
T8386	Esomeprazole Magnesium trihydrate	(S)-Omeprazole magnesium trihydrate	Proton pump
	Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophageal reflux disease in patients with a history of erosive esophagit...		Proton pump
T6531	Heparin sodium salt	Sodium heparinate,Heparin sodium	Factor Xa , Thrombin , Autophagy
	Heparin sodium is a sulfated polysaccharide, which belongs to the family of glycosaminoglycans. It is utilized as an anticoagulant and interacted with diverse proteins for numerous important biological activities.Heparin...		Factor Xa , Thrombin , Autophagy
T22391	Omeprazole Sodium		P450 , Proton pump , Antibacterial , Autophagy
	Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion. Omeprazole Sodium is a potent neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor). Omeprazole Sodium shows competitive...		P450 , Proton pump , Antibacterial , Autophagy
T1021	(R)-Lansoprazole	Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole	Proton pump
	(R)-Lansoprazole (T 168390) is the R-isomer of lansoprazole and a substituted benzimidazole prodrug with selective and irreversible proton pump inhibitor activity.Lansoprazole (AG 1749) is a potent brain penetrant neutra...		Proton pump
T4019	Cambinol	SIRT1/2 Inhibitor IV,NSC 112546	Apoptosis , Phospholipase , Sirtuin
	Cambinol (SIRT1/2 Inhibitor IV) is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 μM, respectively) in a substrate-, but not NAD-, competitive manner. Ca...		Apoptosis , Phospholipase , Sirtuin
T35335	Neticonazole	SS717,Neticonazole
	Neticonazole is a useful organic compound for research related to life sciences. The catalog number is T35335 and the CAS number is 130726-68-0.
T64262	Heparin Lithium salt
	Heparin Lithium salt is an anticoagulant that reversibly binds antithrombin III (ATIII). Heparin Lithium salt markedly blocks exosome-cell interactions.

Compounds

DPTIP

T60043

Synonym:

Target: Phospholipase

Neticonazole Hydrochloride

Target: Antibiotic, Antifungal

Lansoprazole

T0674

Synonym: A-65006,AG-1749

Target: Proton pump, Phospholipase, Antibacterial

U-104

T2017

Synonym: NSC-213841,MST-104

Target: Carbonic Anhydrase

Pantoprazole

T6928

Synonym: SKF96022,BY1023

Target: Apoptosis, Proton pump, Autophagy

Pantoprazole Sodium Hydrate

T0161

Synonym: SKF96022 sodium hydrate,BY1023 (sodium hydrate),SKF96022 (sodium hydrate)

Target: Apoptosis, Potassium Channel, Proton pump, Autophagy

Pantoprazole sodium

T6929

Synonym: Pantecta,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),BY-1023 sodium,Pantoloc

Target: Apoptosis, Others, Proton pump, HIF, Autophagy

Esomeprazole Sodium

T2686L

Synonym: (S)-Omeprazole sodium

Target: ATPase, Proton pump

Esomeprazole Magnesium

T2686

Synonym: (S)-Omeprazole magnesium,NEXIUM,(-)-Omeprazole magnesium

Target: ATPase, Proton pump

GW4869

T3640

Synonym: GW554869A,GW 4869,GW69A

Target: Phospholipase

Sulfisoxazole

T0750

Synonym: NU-445,Sulfafurazole

Target: Endothelin Receptor, Antibacterial, Antibiotic, Autophagy

Synonym: Losec,Prilosec,H 16868,Antra

Target: Proton pump, Phospholipase, Antibacterial, Autophagy

Esomeprazole Magnesium trihydrate

T8386

Synonym: (S)-Omeprazole magnesium trihydrate

Target: Proton pump

Heparin sodium salt

T6531

Synonym: Sodium heparinate,Heparin sodium

Target: Factor Xa, Thrombin, Autophagy

Omeprazole Sodium

T22391

Synonym:

Target: P450, Proton pump, Antibacterial, Autophagy

(R)-Lansoprazole

T1021

Synonym: Dexlansoprazole,T 168390,TAK 390,R-(+)-Lansoprazole

Target: Proton pump

Cambinol

T4019

Synonym: SIRT1/2 Inhibitor IV,NSC 112546

Target: Apoptosis, Phospholipase, Sirtuin

Neticonazole

T35335

Synonym: SS717,Neticonazole

Cat No.	Product Name	Synonyms	Targets
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
T11665	Ionomycin calcium	SQ23377 calcium	Apoptosis , Calcium Channel , Antibacterial , Antibiotic , PKC
	lonomycin calcium is a potent, selective calcium ionophore and an antibiotic produced by Streptomyces conglobatus. also induces the activation of protein kinase C (PKC). Ionomycin calcium (SQ23377 calcium) is highly spec...
T1033	Monensin sodium salt	Sodium Monensin,Monensin A sodium salt	Sodium Channel , Antibacterial , Antibiotic
	Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretion		Sodium Channel , Antibacterial , Antibiotic
T16011	Manumycin A		Prostaglandin Receptor
	Manumycin A is an antibiotic. Manumycin A induces apoptosis and exerts antitumor activity. Manumycin A inhibits exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling. Manumycin A acts as a ...		Prostaglandin Receptor

Natural Products

Forskolin

T2939

Synonym: Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Ionomycin calcium

T11665

Synonym: SQ23377 calcium

Target: Apoptosis, Calcium Channel, Antibacterial, Antibiotic, PKC

Monensin sodium salt

T1033

Synonym: Sodium Monensin,Monensin A sodium salt

Target: Sodium Channel, Antibacterial, Antibiotic

Manumycin A

T16011

Synonym:

Target: Prostaglandin Receptor

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-05325	Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells

TMPK-00768	ANXA1 Protein, Human, Recombinant (His)	Human	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPK-01291	ANXA1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPH-03727	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His)	ZEBOV	E. coli
	Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPH-03728	Zaire ebolavirus (strain Kikwit-95) VP40 Protein (His & Myc)	ZEBOV	Baculovirus
	Plays an essential role virus particle assembly and budding. Acts by interacting with viral ribonucleocapsid and host members of the ESCRT (endosomal sorting complex required for transport) system such as host VPS4, PDCD...
TMPK-00842	CD21 Protein, Human, Recombinant (His)	Human	HEK293
	CD21 mRNA expression, an EBV-entry receptor, was transiently detected in NK cells after exosome treatment, and levels decreased after further culture. CD21 protein expression was also transiently transferred to NK cells ...
TMPK-00799	ANXA1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Atherosclerosis, characterized by the formation of fat-laden plaques, is a chronic inflammatory disease. ABCA1 promotes cholesterol efflux, reduces cellular cholesterol accumulation, and regulates anti-inflammatory activ...
TMPY-02883	C1D Protein, Human, Recombinant (GST)	Human	E. coli
	C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid h...
TMPH-02189	TENT4B Protein, Human, Recombinant (His)	Human	E. coli
	Terminal nucleotidyltransferase that catalyzes preferentially the transfert of ATP and GTP on RNA 3' poly(A) tail creating a heterogeneous 3' poly(A) tail leading to mRNAs stabilization by protecting mRNAs from active de...