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dioxide

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
T60224175340-21-3In house
1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986. S 18986 is a AMPA receptor positive modulator with EC2 (Concentration that doubles the intensity of the AMPA-induced current) of 35 μM.
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ISOTHIAZOLINE 1,1-DIOXIDE
isothiazolidine 1,1-dioxide
T86155908-62-3
ISOTHIAZOLINE 1,1-DIOXIDE (isothiazolidine 1,1-dioxide) is a reactant used in the synthesis of orally bioavailable hebatits B caspid inhibitors, and in the preparation of cryptochrome imhibitors as antidiabetic agents.
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Carbon dioxide reduction factor
Methanofuran,Cdr factor
T3074389873-36-9
Carbon dioxide reduction factor is a coenzyme of methanogenesis from carbon dioxide.
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L-Cystine S,S-dioxide
Cystinedisulfoxide
T3261530452-69-8
L-Cystine S,S-dioxide is a metabolite of L-Cystine.
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Silicon dioxide
T346427631-86-9
Silicon dioxide is a transparent, tasteless crystals found in nature as agate, amethyst, chalcedony, cristobalite, flint, sand, QUARTZ, and tridymite. The compound is insoluble in water or acids except hydrofluoric acid.
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Thiophene-3-ol, 2,3-dihydro-, sulfate, 1,1-dioxide
T3485769071-73-4
Thiophene-3-ol, 2,3-dihydro-, sulfate, 1,1-dioxide is a bioactive chemical.
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Methyl 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylate 1,1-dioxide
T6529659804-25-0
Methyl 4-hydroxy-2-methyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65296 and the CAS number is 59804-25-0.
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    (S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
    T65610154127-42-1
    (S)-4-Hydroxy-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65610 and the CAS number is 154127-42-1.
      7-10 days
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      Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
      T6568824683-26-9
      Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.
        7-10 days
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        Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
        T65943
        Methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences and the catalog number is T65943.
          7-10 days
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          Potassium clavulanate mixture with silicon dioxide (1:1)
          T73955
          Potassium Clavulanate Mixture with Silicon Dioxide (1:1) is a compound consisting of an equal parts ratio, specifically one part Potassium Clavulanate to one part Silicon Dioxide, presented in a powdered form [1].
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          DABCO-Bis(sulfur dioxide)
          TYD-00672119752-83-9
          DABCO-Bis(sulfur dioxide) (DABSO) serves as a source of sulfur dioxide in organic synthesis and is utilized in the preparation of sulfamides and sulfamates.
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          7-10 days
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          Dorzolamide hydrochloride
          MK507 hydrochloride, L671152 hydrochloride, MK-507 (L-671152) HCl, Dorzolamide HCl
          T2134130693-82-2
          Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that catalyzes the rapid conversion of carbon dioxide and water into carbonic acid, protons and bicarbonate ions. Distributed throughout many cells and tissues, various carbonic anhydrases play important roles in mineral and metabolic homeostasis.
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          Trometamol hydrochloride
          TRIS hydrochloride
          T234781185-53-1
          Trometamol hydrochloride (TRIS hydrochloride) (Tromethamine hydrochloride) is a biologically inert amino alcohol with low toxicity. Trometamol hydrochloride buffers carbon dioxide and acids in vitro and in vivo. Trometamol hydrochloride is an effective amine compound for pH control in the physiological range.
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          4-6 weeks
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          1-Nonadecanol
          TN67541454-84-8
          1-Nonadecanol is a saturated fatty alcohol. 1-Nonadecanol is one of the compositions of supercritical carbon dioxide (SC-CO2) essential oil of Heracleum thomsonii. 1-Nonadecanol is also an important aroma compound in Neotinea ustulata.
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          CCR7 Ligand 1
          CCR7-Cmp2105
          T10716681514-83-0
          CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
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          10-14 weeks
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          Sudoxicam
          4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
          T1695034042-85-8
          Sudoxicam (4-Hydroxy-2-methyl-N-2-thiazolyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) is a reversible antagonist of COX with anti-inflammatory, anti-edema, and antipyretic properties.
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          6-8 weeks
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          TMB dihydrochloride x.hydrate
          Sure Blue TMB dihydrochloride x.hydrate
          T200186207738-08-7
          TMB(dihydrochloride x.hydrate) is the dihydrochloride salt and hydrate form of TMB. It is a non-toxic and non-mutagenic colorless dye used as a chromogenic agent in horseradish peroxidase-based assay systems. This compound also serves as a photoacoustic probe for reactive oxygen and nitrogen species (ROS RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce a blue oxidized product. Additionally, TMB(dihydrochloride x.hydrate) can detect singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922.
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          2-4 weeks
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          Pretiadil
          T20209330840-27-8
          Pretiadil is a coronary vasodilator compound derived from thiazole dioxide.
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          PAMAM Dendrimer G0.0 amine
          T203456155773-72-1
          PAMAM Dendrimer G0.0 amine functions as a pore-forming channel antagonist, affecting anthrax toxin protective antigen 63 (PA63, IC50 of 231 nM) and Clostridium botulinum C2 toxin subunit (C2IIa, IC50 of 940 nM). At 10 and 20 µM concentrations, it reduces HeLa cell death induced by C2 toxin. Additionally, PAMAM Dendrimer G0.0 amine acts as a nickel chelator. When combined with a chitosan complex on polysulfone membranes, it selectively captures and stores carbon dioxide (CO2) in gas feed systems. It is utilized in synthesizing PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5). This compound is applicable in research related to infection, cancer, and drug delivery systems.
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          Sepin-1
          Sepin 1, Sepin1, 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide
          T28754163126-81-6
          Sepin-1 is a noncompetitive inhibitor of separase (IC50 = 14.8 µM). Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
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          PTIO
          T3651218390-00-6
          PTIO, a specific scavenger of NO, reacts with nitric oxide to form nitric dioxide and corresponding imino nitroxides. PTIO can be utilized to examine nitric oxide synthase inhibitory activity.
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          9(E),11(E)-12-nitro Conjugated Linoleic Acid
          T372701515620-30-0
          9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma. 1.Woodcock, S.R., Salvatore, S.R., Bonacci, G., et al.Biomimetic nitration of conjugated linoleic acid: Formation and characterization of naturally occurring conjugated nitrodienesJ. Org. Chem.79(1)25-33(2014) 2.Bonacci, G., Baker, P.R.S., Salvatore, S.R., et al.Conjugated linoleic acid is a preferential substrate for fatty acid nitrationJ. Biol. Chem.287(53)44071-44082(2012)
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          Carboxy-PTIO
          T38945145757-47-7
          Carboxy-PTIO is a highly effective nitric oxide (NO) scavenger known for its rapid reaction rate with NO, resulting in the formation of nitric dioxide (NO2). Its direct scavenging action against NO plays a crucial role in preventing hypotension and endotoxic shock, particularly in lipopolysaccharide-stimulated rat models.
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