cs1

CS1 is a potent DNA Topo II α inhibitor that exhibits broad-spectrum antitumor effects in vitro, low toxicity in vivo, and potential anti-multidrug resistance capabilities. CS1 induces DNA damage, G2/M phase cell cycle arrest, and apoptosis [1].

CS1 peptide is present within type III homology connecting segment (IIICS) as well as C-274 (cell-binding domain). Fibronectin CS1 Peptide lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontaneous and experimental metastas

he connecting segment 1 (CS-1) is a cell attachment domain located in the type III homology connecting segment (IIICS) of fibronectin. CS1 peptide of fibronectin, which lacks the Arg-Gly-Asp-containing domain, actively inhibits tumor metastases in spontan

PCS1055 dihydrochloride is an effective, selective, and competitive muscarinic M4 receptor antagonist (IC50: 18.1 nM and a Kd: 5.72 nM). PCS1055 dihydrochloride is also a potent AChE inhibitor (IC50 s: 22 nM and 120 nM for electric eel and human AChE, res

CS12192 is a compound that improves survival and increases body weight and has potential for graft-versus-host disease (GVHD) research.

NCS112200 is TRABID inhibitor

PCS1055 is a selective and competitive antagonist of the muscarinic M4 receptor (muscarinic M4 receptor), with an IC50 of 18.1 nM and a Kd of 5.72 nM. It inhibits the binding of the radioligand [3H]-NMS to the M4 receptor, with a Ki of 6.5 nM. Additionally, PCS1055 acts as an AChE inhibitor, exhibiting IC50 values of 22 nM for electric eel AChE and 120 nM for human AChE.

PDL-241 is a CHO-expressed humanized antibody targeting SLAMF7/CS1. It features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 146.38 kDa. For isotype control, refer to HumanIgG1kappa, Isotype Control.