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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T24706 | RBC10 | RBC 10,RBC-10 | GTPase |
RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-independent growth of human cancer cell lines. | |||
T38048 | Globotetraosylceramides (porcine RBC) | ||
Globotetraosylceramides are bioactive neutral glycosphingolipids. They are the major glycolipids in human erythrocytes. They act as receptors for the Shiga toxins Stx1, Stx2, and Stx2e, the cytotoxic protein pierisin-1, ... | |||
T6634 | RBC8 | GTPase , Ras | |
RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras. | |||
T24707 | RBC6 | RBC-6,RBC 6 | |
RBC6 is an inhibitor of the binding of Ral to its effector RALBP1. | |||
T4223 | Mitapivat | PKR-IN-1 | PKM |
Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency. | |||
T3528 | Senicapoc | ICA-17043 | Potassium Channel |
Senicapoc (ICA-17043) is a potent inhibitor of the Gardos channel and ameliorates RBC dehydration in the SAD mouse. Senicapoc blocked Ca2+-induced rubidium flux from human RBCs with an IC50 value of 11 ± 2 nM (CLT IC50 =... | |||
T4S0590 | Columbin | Phospholipase , COX , Parasite | |
1. Columbin has anti-inflammatory activity. 2. Columbin has chemopreventive ability against human colon cancer. 3. Columbin inhibits PLA2 hydrolysis of ghost RBC in a dose-dependent fashion. | |||
T12399 | Peldesine | BCX 34 | Nucleoside Antimetabolite/Analog , HIV Protease |
Peldesine (BCX 34) is an effective, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase. Peldesine inhibits T-cell proliferation with an IC50 of 800 nM. Peldesine can be used in resear... | |||
T77065 | Ligufalimab | ||
Ligufalimab (AK 117), a humanized IgG4 monoclonal antibody targeting CD47, does not lead to red blood cell (RBC) hemagglutination but promotes phagocytosis and exhibits anti-tumor activity [1]. | |||
T60799 | Peldesine dihydrochloride | ||
Peldesine (BCX 34) dihydrochloride is a potent, competitive, reversible, and orally active inhibitor of purine nucleoside phosphorylase (PNP), exhibiting IC50 values of 36 nM, 5 nM, and 32 nM against human, rat, and mous... | |||
TMA0424 | Martynoside | ROS | |
Martynoside is a natural selective estrogen receptor modulator, which has antioxidative, anti-muscle fatigue, anticancer and antimetastatic activities. Martynoside has the potential of antagonizing sports anaemia, the me... |