20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8841 | IMT1 | Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-,LDC195943(IMT1) | Others , DNA/RNA Synthesis , Mitochondrial Metabolism |
IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity. | |||
T0484 | Deracoxib | SC 46,SC 046,SC 59046 | Apoptosis , COX |
Deracoxib (SC 46) is a non-steroidal, non-narcotic anti-inflammatory drug. It is also a selective cyclooxygenase-2 inhibitor, and IC50 Value: 70 to 150 μM(inhibition of 3 osteosarcoma cell lines). | |||
T30937 | Cimicoxib | UR-8880,UR8880,trade name: Cimalgex | COX |
Cimicoxib (UR8880) is a potent and selective inhibitor of COX-2 with anti-inflammatory and analgesic activity. | |||
T11005 | Desmethyl Celecoxib | COX | |
Demethyl celecoxib is a selective inhibitor of COX-2 with anti-inflammatory activity (IC50 of 32 nM). with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%. | |||
T7596 | Firocoxib | ML 1785713 | COX |
Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses. | |||
T1574 | Etoricoxib | Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine | COX |
Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenas... | |||
T21294 | Polmacoxib | CG-100649,CG100649,CG 100649 | COX , Carbonic Anhydrase |
Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through... | |||
T35610 | 2,5-dimethyl Celecoxib | Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor | |
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ... | |||
T7670 | Mavacoxib | COX | |
Mavacoxib is a selective inhibitor of cyclooxygenase-2 (COX-2) ,with Anti-Tumour activity. | |||
T1780 | Parecoxib | SC 69124,Vorth-P,Valus-P | COX |
Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor. | |||
T1185 | Rofecoxib | MK 966,MK-0966 | COX |
Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of pheny... | |||
T0219 | Valdecoxib | SC 65872 | COX |
Valdecoxib (SC 65872) is a prescription drug used in the treatment of osteoarthritis, rheumatoid arthritis, and painful menstruation and menstrual symptoms. It is classified as a nonsteroidal anti-inflammatory drug, or N... | |||
T6574 | Lumiracoxib | Prexige,COX-189 | COX |
Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4. | |||
T26109 | Robenacoxib | Onsior | COX |
Robenacoxib (Onsior) is a non-steroidal compound with strong selectivity for cyclooxygenase-2 and anti-inflammatory activity. | |||
T0466 | Celecoxib | SC 58635 | COX |
Celecoxib (SC 58635) is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of celecoxib is as a Cyclooxygenase Inhibitor. | |||
T15571 | Imrecoxib | BAP-909 | COX |
Imrecoxib (BAP-909) is a novel and selective cyclooxygenase 2 (COX-2) inhibitor (IC50: 18 nM). It also inhibits COX1- activity (IC50: 115 nM). Imrecoxib has an anti-inflammatory effect. | |||
T15630 | Tilmacoxib | RWJ57504,JTP19605,JTE522 | COX |
Tilmacoxib is a highly selective, time-dependent, and irreversible inhibitor of human COX-2 ( IC50: 85 nM in an enzyme assay). | |||
T37251 | Celecoxib Carboxylic Acid Acyl-β-D-Glucuronide | ||
Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s... | |||
T83327 | 4'-Aarboxylic acid imrecoxib | ||
Imrecoxib-4'-carboxylic acid is a metabolite of Imrecoxib, which acts as a selective COX-II inhibitor [1]. | |||
T24940 | Vitacoxib | ||
Vitacoxib is a selective inhibitor of COX-2. It is used as a novel nonsteroidal anti-inflammatory agent. |